913 research outputs found
Factors influencing the incidence of infections in Felty's syndrome
Contains fulltext :
4466.pdf (publisher's version ) (Open Access
Septicaemia with Dysgonic Fermenter -2 (DF-2) bacterium in a compromised host
Contains fulltext :
4451.pdf (publisher's version ) (Open Access
IL-17 down-regulates the immunosuppressive capacity of olfactory ecto-mesenchymal stem cells in murine collagen-induced arthritis
published_or_final_versio
The efficacy of itraconazole against systemic fungal infections in neutropenic patients : a randomised comparative study with amphotericin B
Contains fulltext :
4533.pdf (publisher's version ) (Open Access
Immunomodulatory properties of mesenchymal stem cells : a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005
Peer reviewedPublisher PD
Cytokine-induced hematopoietic stem and progenitor cell mobilization: unraveling interactions between stem cells and their niche
Peripheral blood hematopoietic stem and progenitor cells (HSPCs), mobilized by granulocyte colony-stimulating factor, are widely used as a source for both autologous and allogeneic stem cell transplantation. The use of mobilized HSPCs has several advantages over traditional bone marrow-derived HSPCs, including a less invasive harvesting process for the donor, higher HSPC yields, and faster hematopoietic reconstitution in the recipient. For years, the mechanisms by which cytokines and other agents mobilize HSPCs from the bone marrow were not fully understood. The field of stem cell mobilization research has advanced significantly over the past decade, with major breakthroughs in the elucidation of the complex mechanisms that underlie stem cell mobilization. In this review, we provide an overview of the events that underlie HSPC mobilization and address the relevant cellular and molecular components of the bone marrow niche. Furthermore, current and future mobilizing agents will be discussed
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