Lattice three-gluon vertex in extended kinematics: planar degeneracy

We present novel results for the three-gluon vertex, obtained from an extensive quenched lattice simulation in the Landau gauge. The simulation evaluates the transversely projected vertex, spanned on a special tensorial basis, whose form factors are naturally parametrized in terms of individually Bose-symmetric variables. Quite interestingly, when evaluated in these kinematics, the corresponding form factors depend almost exclusively on a single kinematic variable, formed by the sum of the squares of the three incoming four-momenta, $q$, $r$, and $p$. Thus, all configurations lying on a given plane in the coordinate system $(q^2, r^2, p^2)$ share, to a high degree of accuracy, the same form factors, a property that we denominate \emph{planar degeneracy}. We have confirmed the validity of this property through an exhaustive study of the set of configurations satisfying the condition $q^2 = r^2$, within the range $[0, 5\, \rm GeV]$. Moreover, a preliminary exploration reveals that the planar degeneracy persist in the case of more arbitrary configurations. This drastic simplification allows for a remarkably compact description of the main bulk of the data, which is particularly suitable for future numerical applications. A semi-perturbative analysis reproduces the lattice findings rather accurately, once the inclusion of a gluon mass has cured all spurious divergences.Comment: 8 pages, 7 figure

Lattice three-gluon vertex in extended kinematics: Planar degeneracy

We present novel results for the three-gluon vertex, obtained from an extensive quenched lattice simulation in the Landau gauge. The simulation evaluates the transversely projected vertex, spanned on a special tensorial basis, whose form factors are naturally parametrized in terms of individually Bose-symmetric variables. Quite interestingly, when evaluated in these kinematics, the corresponding form factors depend almost exclusively on a single kinematic variable, formed by the sum of the squares of the three incoming four-momenta, q, r, and p. Thus, all configurations lying on a given plane in the coordinate system (q2,r2,p2) share, to a high degree of accuracy, the same form factors, a property that we denominate planar degeneracy. We have confirmed the validity of this property through an exhaustive study of the set of configurations satisfying the condition q2=r2, within the range [0,5GeV]. This drastic simplification allows for a remarkably compact description of the main bulk of the data, which is particularly suitable for future numerical applications. A semi-perturbative analysis reproduces the lattice findings rather accurately, once the inclusion of a gluon mass has cured all spurious divergences.The authors thank A. C. Aguilar, G. Eichmann and C. D. Roberts for useful discussions. M.N.F. acknowledges financial support from the FAPESP projects 2017/05685-2 and 2020/12795-1, respectively. J.P. is supported by the Spanish MICINN grant PID2020-113334GB-I00 and the regional Prometeo/2019/087 from the Generalitat Va-lenciana; while F.D.S. and J.R.Q. are by the Spanish MICINN grant PID2019-107844GB-C22 and the regional Andalusian P18-FR-5057. All calculations have been performed at the UPO computing center, C3UPO

Study of the combination of self-activating photodynamic therapy and chemotherapy for cancer treatment

Cancer is a very challenging disease to treat, both in terms of treatment eficiency and side-effects. To overcome these problems, there have been extensive studies regarding the possibility of improving treatment by employing combination therapy, and by exploring therapeutic modalities with reduced side-effects (such as photodynamic therapy (PDT)). Herein, this work has two aims: (i) to develop self-activating photosensitizers for use in light-free photodynamic therapy, which would eliminate light-related restrictions that this therapy currently possesses; (ii) to assess their co-treatment potential when combined with reference chemotherapeutic agents (Tamoxifen and Metformin). We synthesized three new photosensitizers capable of self-activation and singlet oxygen production via a chemiluminescent reaction involving only a cancer marker and without requiring a light source. Cytotoxicity assays demonstrated the cytotoxic activity of all photosensitizers for prostate and breast tumor cell lines. Analysis of co-treatment effects revealed significant improvements for breast cancer, producing better results for all combinations than just for the individual photosensitizers and even Tamoxifen. By its turn, co-treatment for prostate cancer only presented better results for one combination than for just the isolated photosensitizers and Metformin. Nevertheless, it should be noted that the cytotoxicity of the isolated photosensitizers in prostate tumor cells was already very appreciable.This research was co-funded by Fundação para a Ciência e Tecnologia (FCT) and FEDER through COMPETE-POFC, grant number PTDC/QEQ-QFI/0289/2014; funded by FEDER through COMPETE2020, grant POCI-01-0145-FEDER-006980; funded by FEDER through NORTE2020, grant number NORTE-01-0145-FEDER 000028; co-funded by Fundação para a Ciência e Tecnologia (FCT) and FEDER through COMEPETE2020-POCI, grant number POCI-01-0145-FEDER-007274; co-funded by Fundação para a Ciência e Tecnologia (FCT) and FEDER, grant number IF/00092/2014/CP1255/CT0004; funded by Fundação para a Ciência e Tecnologia (FCT), grant number SFRH/BD/140734/2018; funded by Fundação para a Ciência e Tecnologia (FCT), grant number UID/QUI/50006/2013; funded by Fundação para a Ciência e Tecnologia (FCT), grant number PTDC/BIA-MIA/29059/2017; funded by Fundação para a Ciência e Tecnologia (FCT), grant number CEECIND/01425/2017; funded by Fundação para a Ciência e Tecnologia (FCT), grant number SFRH/BD/143211/2019

Ghost dynamics in the soft gluon limit

We present a detailed study of the dynamics associated with the ghost sector of quenched QCD in the Landau gauge, where the relevant dynamical equations are supplemented with key inputs originating from large-volume lattice simulations. In particular, we solve the coupled system of Schwinger-Dyson equations that governs the evolution of the ghost dressing function and the ghost-gluon vertex, using as input for the gluon propagator lattice data that have been cured from volume and discretization artifacts. In addition, we explore the soft gluon limit of the same system, employing recent lattice data for the three-gluon vertex that enters in one of the diagrams defining the Schwinger-Dyson equation of the ghost-gluon vertex. The results obtained from the numerical treatment of these equations are in excellent agreement with lattice data for the ghost dressing function, once the latter have undergone the appropriate scale-setting and artifact elimination refinements. Moreover, the coincidence observed between the ghost-gluon vertex in general kinematics and in the soft gluon limit reveals an outstanding consistency of physical concepts and computational schemes.Comment: 34 pages, 12 figure

Schwinger mechanism for gluons from lattice QCD

Continuum and lattice analyses have revealed the existence of a mass-scale in the gluon two-point Schwinger function. It has long been conjectured that this expresses the action of a Schwinger mechanism for gauge boson mass generation in quantum chromodynamics (QCD). For such to be true, it is necessary and sufficient that a dynamically-generated, massless, colour-carrying, scalar gluon+gluon correlation emerge as a feature of the dressed three-gluon vertex. Working with results on elementary Schwinger functions obtained via the numerical simulation of lattice-regularised QCD, we establish with an extremely high level of confidence that just such a feature appears; hence, confirm the conjectured origin of the gluon mass scale.Comment: 8 pages, 8 figure

AMI observations of unmatched Planck ERCSC LFI sources at 15.75 GHz

The Planck Early Release Compact Source Catalogue includes 26 sources with no obvious matches in other radio catalogues (of primarily extragalactic sources). Here we present observations made with the Arcminute Microkelvin Imager Small Array (AMI SA) at 15.75 GHz of the eight of the unmatched sources at declination > +10 degrees. Of the eight, four are detected and are associated with known objects. The other four are not detected with the AMI SA, and are thought to be spurious.Comment: 6 pages, 5 figures, 4 table

Demonstration of the event identification capabilities of the NEXT-White detector

In experiments searching for neutrinoless double-beta decay, the possibility of identifying the two emitted electrons is a powerful tool in rejecting background events and therefore improving the overall sensitivity of the experiment. In this paper we present the first measurement of the efficiency of a cut based on the different event signatures of double and single electron tracks, using the data of the NEXT-White detector, the first detector of the NEXT experiment operating underground. Using a 228Th calibration source to produce signal-like and background-like events with energies near 1.6 MeV, a signal efficiency of 71.6 ± 1.5 stat± 0.3 sys% for a background acceptance of 20.6 ± 0.4 stat± 0.3 sys% is found, in good agreement with Monte Carlo simulations. An extrapolation to the energy region of the neutrinoless double beta decay by means of Monte Carlo simulations is also carried out, and the results obtained show an improvement in background rejection over those obtained at lower energies. [Figure not available: see fulltext.

Radiogenic backgrounds in the NEXT double beta decay experiment

Natural radioactivity represents one of the main backgrounds in the search for neutrinoless double beta decay. Within the NEXT physics program, the radioactivity- induced backgrounds are measured with the NEXT-White detector. Data from 37.9 days of low-background operations at the Laboratorio Subterráneo de Canfranc with xenon depleted in 136Xe are analyzed to derive a total background rate of (0.84±0.02) mHz above 1000 keV. The comparison of data samples with and without the use of the radon abatement system demonstrates that the contribution of airborne-Rn is negligible. A radiogenic background model is built upon the extensive radiopurity screening campaign conducted by the NEXT collaboration. A spectral fit to this model yields the specific contributions of 60Co, 40K, 214Bi and 208Tl to the total background rate, as well as their location in the detector volumes. The results are used to evaluate the impact of the radiogenic backgrounds in the double beta decay analyses, after the application of topological cuts that reduce the total rate to (0.25±0.01) mHz. Based on the best-fit background model, the NEXT-White median sensitivity to the two-neutrino double beta decay is found to be 3.5σ after 1 year of data taking. The background measurement in a Qββ±100 keV energy window validates the best-fit background model also for the neutrinoless double beta decay search with NEXT-100. Only one event is found, while the model expectation is (0.75±0.12) events. [Figure not available: see fulltext.]

Low-diffusion Xe-He gas mixtures for rare-event detection: electroluminescence yield

High pressure xenon Time Projection Chambers (TPC) based on secondary scintillation (electroluminescence) signal amplification are being proposed for rare event detection such as directional dark matter, double electron capture and double beta decay detection. The discrimination of the rare event through the topological signature of primary ionisation trails is a major asset for this type of TPC when compared to single liquid or double-phase TPCs, limited mainly by the high electron diffusion in pure xenon. Helium admixtures with xenon can be an attractive solution to reduce the electron diffu- sion significantly, improving the discrimination efficiency of these optical TPCs. We have measured the electroluminescence (EL) yield of Xe–He mixtures, in the range of 0 to 30% He and demonstrated the small impact on the EL yield of the addition of helium to pure xenon. For a typical reduced electric field of 2.5 kV/cm/bar in the EL region, the EL yield is lowered by ∼ 2%, 3%, 6% and 10% for 10%, 15%, 20% and 30% of helium concentration, respectively. This decrease is less than what has been obtained from the most recent simulation framework in the literature. The impact of the addition of helium on EL statistical fluctuations is negligible, within the experimental uncertainties. The present results are an important benchmark for the simulation tools to be applied to future optical TPCs based on Xe-He mixtures. [Figure not available: see fulltext.]

Energy calibration of the NEXT-White detector with 1% resolution near Q ββ of 136Xe

Excellent energy resolution is one of the primary advantages of electroluminescent high-pressure xenon TPCs. These detectors are promising tools in searching for rare physics events, such as neutrinoless double-beta decay (ββ0ν), which require precise energy measurements. Using the NEXT-White detector, developed by the NEXT (Neutrino Experiment with a Xenon TPC) collaboration, we show for the first time that an energy resolution of 1% FWHM can be achieved at 2.6 MeV, establishing the present technology as the one with the best energy resolution of all xenon detectors for ββ0ν searches. [Figure not available: see fulltext.