1,298 research outputs found
Effect of a cyanobacterial community on calcium carbonate precipitation in Puente del Inca (Mendoza, Argentina)
The involvement of cyanobacteria in the precipitation process forming calcium carbonate was studied in samples collected at a geothermal spring located in an area close to Puente del Inca (Mendoza, Argentina). In the summer season profuse cyanobacterial growth is
observed at Puente del Inca in areas exposed to sunlight and over which thermal water flows. Differences in cellular structure allowed the recognition of strains of Oscillatoria, Spirulina, Plectonema, and Nostoc, Oscillatoria and Spirulina being the dominant species.
The mass cultivation of Oscillatoria sp. was obtained using a new culture medium (BW3) PI which was formulated according to the chemical composition of the thermal water. On a dry-weight basis the biomass concentration was 0.88 g L–1 at pH 7.5 and 0.44 g L–1
with a free pH evolution after 11 days of incubation. The increase of pH associated with Oscillatoria sp. growth triggered calcium carbonate precipitation at values higher than 8.1. The events observed under laboratory conditions are likely to occur in situ as a consequence
of cyanobacterial growth in the saturated thermal water of Puente del Inca
Medico-legal matters and Australian doctors : an investigation of doctors' experience of medico-legal matters, their mental health and their practice of medicine
Single location muscle monitoring does not reflect the heterogeneous activation of the muscle group(s) during a given exercise. Vastus lateralis and rectus femoris O2 consumption (VO2) was investigated, noninvasively, at rest and during maximal voluntary contractions (MVC) using a 12-channel near-infrared continuous wave spectroscopy (NIR(CWS)) system (0.1 s acquisition time). VO2 either at rest or during MVC was found to be nonuniform in the 11 out of 12 measurement sites over a surface of 8 x 8 cm2. As expected, VO2 during exercise was significantly higher than VO2 at rest (P < 0.01). However, at each muscle measurement site no difference was found between the mean values (n = 12) of VO2 measured during a 5-s intermittent MVC and the VO2 values measured during 30-s continuous MVC (P = 0.25). These results strengthen the role of NIR(CWS) as a powerful tool for investigating the spatial and temporal features of muscle oxygenation changes as well as muscle VO2
Virtual materials for the prediction of concrete mechanical properties
Physical properties such as compressive strength and elastic moduli are of the utmost importance for the structural stability and design of cement-based materials. These properties are strictly related to the microstructure of the binder paste, which in turn varies in time, as a function of the hydration kinetics. Therefore, the development of the elastic properties and mechanical strength can in principle be controlled by affecting the microstructure and hydration kinetics. This can be achieved through an appropriate mix-design, which encompasses a careful selection of phase proportions, grain-size distribution, amount of water and aggregates, and use of additives. Changing such variables by a trial-and-error process can be extremely time consuming and has a significant impact in terms of resources employed. Moreover, a fully quantitative approach to the study of the cement microstructure and hydration kinetics requires significant efforts in terms of experimental testing, often encompassing analytical techniques such as X-ray diffraction, scanning electron microscopy and isothermal calorimetry, among others. In this contribution, an alternative quantitative characterization of the cement paste in time is illustrated, based on the numerical modeling of cement-based systems. Virtual cement pastes and mortars are generated using the software VCCTL (http://www.nist.gov/el/building_materials/inorganic/vcctl.cfm), using as input parameters the clinker phase composition, the water/cement ratio, and the size and shape distribution of the particles. The elastic moduli and compressive strength of such virtual samples is then computed from the developed microstructure by a finite element method. Extensive calibration and testing has been performed against experimental data, and the good agreement between the calculated and measured elastic and mechanical properties shows that VCCTL can be used as a truly predictive tool. Although experimental testing remains a fundamental aspect of concrete science, the coupling of experiments with computational methods provides a viable tool towards a knowledge-based mix design, with a potential reduction of costs and environmental impact
Virtual materials for the prediction of concrete mechanical properties
Physical properties such as compressive strength and elastic moduli are of the utmost importance for the structural stability and design of cement-based materials. These properties are strictly related to the microstructure of the binder paste, which in turn varies in time, as a function of the hydration kinetics. Therefore, the development of the elastic properties and mechanical strength can in principle be controlled by affecting the microstructure and hydration kinetics. This can be achieved through an appropriate mix-design, which encompasses a careful selection of phase proportions, grain-size distribution, amount of water and aggregates, and use of additives. Changing such variables by a trial-and-error process can be extremely time consuming and has a significant impact in terms of resources employed. Moreover, a fully quantitative approach to the study of the cement microstructure and hydration kinetics requires significant efforts in terms of experimental testing, often encompassing analytical techniques such as X-ray diffraction, scanning electron microscopy and isothermal calorimetry, among others. In this contribution, an alternative quantitative characterization of the cement paste in time is illustrated, based on the numerical modeling of cement-based systems. Virtual cement pastes and mortars are generated using the software VCCTL (http://www.nist.gov/el/building_materials/inorganic/vcctl.cfm), using as input parameters the clinker phase composition, the water/cement ratio, and the size and shape distribution of the particles. The elastic moduli and compressive strength of such virtual samples is then computed from the developed microstructure by a finite element method. Extensive calibration and testing has been performed against experimental data, and the good agreement between the calculated and measured elastic and mechanical properties shows that VCCTL can be used as a truly predictive tool. Although experimental testing remains a fundamental aspect of concrete science, the coupling of experiments with computational methods provides a viable tool towards a knowledge-based mix design, with a potential reduction of costs and environmental impact
Design of an Efficient Pumping Scheme for Mid-IR Dy3+:Ga5Ge20Sb10S65PCF Fiber Laser
This letter illustrates the design of a novel medium infrared (Mid-IR) laser based on a photonic crystal fiber made of dysprosium-doped chalcogenide glass, Dy3+:Ga5Ge20Sb10S65. In order to perform a realistic investigation, the simulation is performed by taking into account the spectroscopic parameters measured on the rare earth-doped glass sample. The simulated results show that an optical beam emission close to 4400-nm wavelength can be obtained by employing two pump beams at 2850 nm (pump #1) and 4092 nm (pump #2) wavelengths. As example, for the pump powers of 50 mW (pump #1) and 1 W (pump #2), the input mirror reflectivity of 99%, the output mirror reflectivity of 30%, and the optical cavity length of 50 cm, a signal power close to 350 mW at the wavelength of 4384 nm can be generated. This result indicates that the designed source configuration is feasible for high beam quality Mid-IR light generation and it is efficient enough to find applications in optical free propagation links, optical remote sensing, and medicine
Field cancerization therapy with ingenol mebutate contributes to restoring skin-metabolism to normal-state in patients with actinic keratosis: a metabolomic analysis
Actinic keratosis (AK) is a skin premalignant lesion, which progresses into squamous cell carcinoma (SCC) if left untreated. Ingenol mebutate gel is approved for local treatment of non-hyperkeratotic, non-hypertrophic AK; it also has the potential to act as a field cancerization therapy to prevent the progression of AK to SCC. To gain better insights into the mechanisms of ingenol mebutate beyond the mere clinical assessment, we investigated, for the first time, the metabolome of skin tissues from patients with AK, before and after ingenol mebutate treatment, with high-resolution magic angle spinning nuclear magnetic resonance spectroscopy. The metabolomic profiles were compared with those of tissues from healthy volunteers. Overall, we identified a number of metabolites, the homeostasis of which became altered during the process of tumorigenesis from healthy skin to AK, and was restored, at least partially, by ingenol mebutate therapy. These metabolites may help to attain a better understanding of keratinocyte metabolism and to unmask the metabolic pathways related to cell proliferation. These results provide helpful information to identify biomarkers with prognostic and therapeutic significance in AK, and suggest that field cancerization therapy with ingenol mebutate may contribute to restore skin metabolism to a normal state in patients with AK
Novel pumping schemes of Mid-IR photonic crystal fiber lasers for aerospace applications
The paper illustrates the design of two pumping schemes for Mid-IR lasers based on photonic crystal fibers (PCFs) made of dysprosium doped chalcogenide glass Dy3+:Ga5Ge20Sb10S65. The simulation is performed by taking into account the spectroscopic parameters measured on the rare earth-doped glass sample in order to perform a realistic feasibility investigation. The first pump scheme provides an optical beam emission close to 4400 nm wavelength by employing two pump beams at the wavelengths close to 2800 nm and 4100 nm, respectively. The second pump scheme allows beam emission close to 4400 nm wavelength via a 1700 nm pump, its efficiency is increased by including a suitable optical amplifier after the laser cavity. The proposed light sources based on chalcogenide glass photonic crystal fibers (PCFs) doped with Dy3+ ions are investigated via a home-made numerical model based on the coupled mode theory and solving the rare earth rate equations. A number of promising applications in different areas such as satellite remote sensing and aerospace, biology, molecular spectroscopy and environmental monitoring are feasible
Helminth community of an alpine rock partridge (Alectoris græca) population in demographic crash
Alpine rock partridge (Alectoris gr\ue6ca) populations are drastically decreasing mainly due to habitat degradation and climate change. From 2003 to 2011, we investigate the helminth community of a rock partridge population from Lepontine Alps (Western Alps), showing a demographic crash in the last few years (2009-2010-2011), to analyse the helminth distribution within population in relation to different factors (sampling year, age, gender) and to disclose the parasites\u2019 role in this population trend.
From 213 intestinal contents of hunted rock partridges we recorded Ascaridia compar, Heterakis gallinarum and Aoncotheca caudinflata: the most abundant species is H. gallinarum with a significant greater abundance in adults. A significant increase of abundance of all the three helminths was recorded in 2010. Juveniles and females were infected by the three helminths while in males we recorded H. gallinarum and A. caudinflata with lower abundances and prevalence.
Data show a temporal association between the demographical population crash and the abundance peak of all the three helminths suggesting a possible health impact of parasites. Even if data did not show any effect of parasites on body weights, the known effects of these parasites on fecundity indicate the likely effect of parasites as a predisposing factor for the observed demographic crash and points out the importance of the health monitoring in wildlife
Thickness Estimation of Epitaxial Graphene on SiC using Attenuation of Substrate Raman Intensity
A simple, non-invasive method using Raman spectroscopy for the estimation of
the thickness of graphene layers grown epitaxially on silicon carbide (SiC) is
presented, enabling simultaneous determination of thickness, grain size and
disorder using the spectra. The attenuation of the substrate Raman signal due
to the graphene overlayer is found to be dependent on the graphene film
thickness deduced from X-ray photoelectron spectroscopy and transmission
electron microscopy of the surfaces. We explain this dependence using an
absorbing overlayer model. This method can be used for mapping graphene
thickness over a region and is capable of estimating thickness of multilayer
graphene films beyond that possible by XPS and Auger electron spectroscopy
(AES).Comment: 14 pages, 9 figure
Myocardial effective transverse relaxation time T(2)* is elevated in hypertrophic cardiomyopathy: a 7.0 T magnetic resonance imaging study
Hypertrophic cardiomyopathy (HCM) is the most common genetic disease of the myocardium and bares the risk of progression to heart failure or sudden cardiac death. Identifying patients at risk remains an unmet need. Recognizing the dependence of microscopic susceptibility on tissue microstructure and on cardiac macromorphology we hypothesized that myocardial T2* might be altered in HCM patients compared to healthy controls. To test this hypothesis, myocardial T2*-mapping was conducted at 7.0 Tesla to enhance T2*-contrast. 2D CINE T2*-mapping was performed in healthy controls and HCM patients. To ensure that T2* is not dominated by macroscopic magnetic field inhomogeneities, volume selective B0 shimming was applied. T2* changes in the interventricular septum across the cardiac cycle were analyzed together with left ventricular radius and ventricular septal wall thickness. The results show that myocardial T2* is elevated throughout the cardiac cycle in HCM patients compared to healthy controls. A mean septal T2* = 13.7 ± 1.1 ms (end-systole: T2*,systole = 15.0 ± 2.1, end-diastole: T2*,diastole = 13.4 ± 1.3 ms, T2*,systole/T2*,diastole ratio = 1.12) was observed in healthy controls. For HCM patients a mean septal T2* = 17.4 ± 1.4 ms (end-systole: T2*,systole = 17.7 ± 1.2 ms, end-diastole: T2*,diastole = 16.2 ± 2.5 ms, T2*,systole/T2*,diastole ratio = 1.09) was found. Our preliminary results provide encouragement that assessment of T2* and its changes across the cardiac cycle may benefit myocardial tissue characterization in HCM
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