1,547 research outputs found

    Fisica dell'accrescimento

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    Questo elaborato presenta una descrizione del fenomeno dell’accrescimento di materia su oggetti compatti, esponendo i principali modelli fisici a riguardo. Dopo un’introduzione, in cui viene mostrato come l’accrescimento rappresenti la più importante fonte di energia in astrofisica, si discute nel capitolo 1 il più semplice modello di accresci- mento, dovuto ad Hermann Bondi (1952). Tale modello, proprio per la sua semplicità, risulta molto importante, nonostante trascuri importanti aspetti fisici. Nel capitolo 2 si studia la fisica dei dischi di accrescimento, analizzando sia il caso generale che alcuni casi particolari, come quello stazionario o a viscosità costante. L’elaborato si conclude con una breve analisi dell’emissione termica da parte del disco di accrescimento

    The MUSE project. Improving access, participation and learning of students with disability in Latin American universities.

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    This paper aims to present the activities carried out within the MUSE European Project, with specific regard to the Work Package \u201cModernization and Strengthening of Human Capital\u201d, led by University of Bologna. One of the main goal of this project is the creation \u2013 in Chile, Mexico and Argentina \u2013 of Students with disabilities Support Centres and long-term strategies for the access and retention of students with disabilities in the Higher Education system. In order to design and create these Support Centres, the University of Bologna trained 30 administrative and academic staff from Latin America on the main conceptual issues related to: Inclusive Approach, Universal Design for Learning, ICT for inclusion and pedagogical design of active learning environment. The training aims to provide pedagogical and didactic competences \u2013 in particular on the use of ICT \u2013 to foster the inclusion of students with disability at university

    Efficacy, safety, and patient acceptability of thecombined chlormadinone acetate-ethinylestradioloral contraceptive

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    Since their introduction in 1959, development of hormonal contraceptives has beenongoing, with the ultimate aim of creating not only an effective and safe contraceptive method,but also a drug able to meet the need for treatment of other conditions, such as acne, seborrhea,and hirsutism, with few or no side effects. With this objective, a new progestin, chlormadinoneacetate (CMA), has been developed as a derivative of progesterone for contraception.Thisnew molecule has been introduced in combination with ethinylestradiol (EE) 30 μg as a safecontraceptivewith antiandrogenic properties. Many clinical studies have investigated this neworal combination and found it to be safe, with a Pearl Index similar to that of other combinedhormonal contraceptives. CMA, because of its antiandrogenic properties, has been also consideredeffective for resolution of acne, seborrhea, and hirsutism. The data show it to be asafe molecule in terms of glucose and lipid metabolism. No major weight changes have beenlinked with its use, and it seems to be the only progestin able to reduce fat mass during use.The CMA-EE combination is well tolerated and acceptable to women. Adverse events relatedto its use are similar to those reported with other third-generation contraceptives.We canconclude that CMA-EE is an effective, safe, and well tolerated antiandrogenichormonalcontraceptive

    Use of Knee Fractures Physical Replicas for Surgical Training and Rehearsal: Proof of Concept Study

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    In the last years also in orthopedic surgery, there was an increasing interest in the development of surgical simulators using methods of additive manufacturing combined or not with augmented reality systems (hybrid simulators). Aim of this work was to evaluate the use of a new patient’s specific tibial plateau fractures simulator for surgical training of young resident surgeons in fracture fixation with an external fixator. The simulator is a realistic knee phantom including a patient-specific replica of a fractured tibia and fibula, obtained by CT segmentation and rapid prototyping techniques. Each training session started with the presentation, and planning, of the surgical case that it was followed by the external fixation session on the simulator. At the end of each session, all participants were asked to fill out a questionnaire, concerning the phantom realism and appropriateness as a teaching modality. The results of the Likert Questionnaire indicating that there is an overall significant agreement with the phantom realism and its appropriateness as a teaching modality. The solid model of the patient’s anatomy can faithfully reproduce the surgical complexity of the patient and it allows to generate surgical simulators with an increasing difficulty to perform structured training paths: from the "simple" case to the "complex" case. The use of simulators based on 3D models has proved to be a very useful tool both for didactic and surgical training purposes, allowing surgeons to perform a real procedure simulation outside the surgical room

    Eradication of Helicobacter pylori infection in patients with duodenal ulcer and non-ulcer dyspepsia and analysis of one-year reinfection rates

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    Helicobacter pylori (HP) infection is endemic worldwide. The proposed treatment is expensive and there are few reports regarding reinfection rates in Brazil. The aim of this study was to compare the eradication rates obtained with two therapeutic options and to evaluate reinfection one year after treatment. This was a prospective randomized trial with 55 patients. Thirty-nine patients had active duodenal ulcer (DU) and 16 non-ulcer dyspepsia (NUD), and all tested positive for HP. Diagnosis was based on at least two positive tests: ultrarapid urease test, histology and/or culture. Patients were randomized to two groups: group OMC treated with 40 mg omeprazole (once a day), 500 mg metronidazole and 250 mg clarithromycin (twice daily) for 7 days, or group NA treated with 300 mg nizatidine (once a day) and 1000 mg amoxicillin (twice daily) for 14 days. Those patients in whom HP was eradicated were followed up for one year to evaluate reinfection. Twenty-five patients were randomized for OMC and 30 for NA. HP eradication occurred in 20/25 patients (80%) treated with OMC and 13/30 (43%) treated with NA (P = 0.01). After reallocation because of initial treatment failure, the overall eradication rate was 44/51 patients (86%). After an average follow-up of one year, we evaluated 34 patients (23 with DU and 11 with NUD). Reinfection occurred in 3/34 patients (7.6%). We conclude that OMC is effective for HP eradication, and that NA should not be used. Reinfection occurs in 7.6% of the patients in the first year after eradication.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Divisão de GastroenterologiaUNIFESP, EPM, Divisão de GastroenterologiaSciEL
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