66 research outputs found
Good practice guide for calibrating a hydrophone "in situ" with a non-omnidirectional source at 10 kHz (26-34)
The aim of this paper is to provide the basis for the calibration of a hydrophonePeer ReviewedPostprint (published version
Empirical acoustic attenuation of the seawater
This study aims to estimate a model for the
underwater acoustic environment in a Mediterranean area and to
compare the model with existing other models of the sound
attenuation in the zone of interest. The contribution of this paper
is to develop a protocol to validate and adjust the offshore
underwater attenuation models to a model of a Mediterranean
area.Peer ReviewedPostprint (author’s final draft
Initial study of the background noise level variation at the shore Mediterranean sea
The aim of the paper is shows the variation of the background noise level located in the shore Mediterranean
Sea using the data acquired by the OBSEA’s hydrophone during a period of time of 4 months, from April 2015 to June 2015Postprint (published version
Initial study of the background noise level variation at the shore mediterranean sea
The aim of the paper is shows the variation of the background noise level
located in the shore Mediterranean Sea using the data acquires by the OBSEA’s hydrophone
during a period of time of 4 months, from April 2015 to June 2015.
Keywords- Hydrophone, background noise level, OBSEAPeer Reviewe
In-depth transcriptomic analysis of human retina reveals molecular mechanisms underlying diabetic retinopathy
Diabetic Retinopathy (DR) is among the major global causes for vision loss. With the rise in diabetes prevalence, an increase in DR incidence is expected. Current understanding of both the molecular etiology and pathways involved in the initiation and progression of DR is limited. Via RNA-Sequencing, we analyzed mRNA and miRNA expression profiles of 80 human post-mortem retinal samples from 43 patients diagnosed with various stages of DR. We found differentially expressed transcripts to be predominantly associated with late stage DR and pathways such as hippo and gap junction signaling. A multivariate regression model identified transcripts with progressive changes throughout disease stages, which in turn displayed significant overlap with sphingolipid and cGMP-PKG signaling. Combined analysis of miRNA and mRNA expression further uncovered disease-relevant miRNA/mRNA associations as potential mechanisms of post-transcriptional regulation. Finally, integrating human retinal single cell RNA-Sequencing data revealed a continuous loss of retinal ganglion cells, and Müller cell mediated changes in histidine and β-alanine signaling. While previously considered primarily a vascular disease, attention in DR has shifted to additional mechanisms and cell-types. Our findings offer an unprecedented and unbiased insight into molecular pathways and cell-specific changes in the development of DR, and provide potential avenues for future therapeutic intervention
Integral chain management of wildlife diseases
The chytrid fungus Batrachochytrium dendrobatidis has caused the most prominent loss of vertebrate diversity ever recorded, which peaked in the 1980s. Recent incursion by its sister species B. salamandrivorans in Europe raised the alarm for a new wave of declines and extinctions in western Palearctic urodeles. The European Commission has responded by restricting amphibian trade. However, private amphibian collections, the main end consumers, were exempted from the European legislation. Here, we report how invasion by a released, exotic newt coincided with B. salamandrivorans invasion at over 1000 km from the nearest natural outbreak site, causing mass mortality in indigenous marbled newts (Triturus marmoratus), and posing an acute threat to the survival of nearby populations of the most critically endangered European newt species (Montseny brook newt, Calotriton arnoldi). Disease management was initiated shortly after detection in a close collaboration between policy and science and included drastic on site measures and intensive disease surveillance. Despite these efforts, the disease is considered temporarily contained but not eradicated and continued efforts will be necessary to minimize the probability of further pathogen dispersal. This precedent demonstrates the importance of tackling wildlife diseases at an early stage using an integrated approach, involving all stakeholders and closing loopholes in existing regulations
Balance de incertidumbres en la calibración "in situ" de un hidrófono
El objetivo de este artÃculo es poner en relieve la posibilidad de la calibración de los hidrófonos en su medio. Con esta finalidad se detallaran los parámetros a tener en cuenta, se propondrán sistemáticas de obtención de los parámetros y se estimarán las contribuciones a la incertidumbre de cada una de ellas mediante la asignación de la distribución de probabilidad adecuada en cada caso.Postprint (published version
Stress deficits in reward behaviour are associated with and replicated by dysregulated amygdala-nucleus accumbens pathway function in mice
Reduced reward interest/learning and reward-to-effort valuation are distinct, common symptoms in neuropsychiatric disorders for which chronic stress is a major aetiological factor. Glutamate neurons in basal amygdala (BA) project to various regions including nucleus accumbens (NAc). The BA-NAc neural pathway is activated by reward and aversion, with many neurons being monovalent. In adult male mice, chronic social stress (CSS) leads to reduced discriminative reward learning (DRL) associated with decreased BA-NAc activity, and to reduced reward-to-effort valuation (REV) associated, in contrast, with increased BA-NAc activity. Chronic tetanus toxin BA-NAc inhibition replicates the CSS-DRL effect and causes a mild REV reduction, whilst chronic DREADDs BA-NAc activation replicates the CSS effect on REV without affecting DRL. This study provides evidence that stress disruption of reward processing involves the BA-NAc neural pathway; the bi-directional effects implicate opposite activity changes in reward (learning) neurons and aversion (effort) neurons in the BA-NAc pathway following chronic stress
Microbial community dynamics in two-chambered microbial fuel cells : effect of different ion exchange membranes
BACKGROUND: The utilization of different kinds of ion exchange membrane is a common practice in bioelectrochemical systems such as two-chambered microbial fuel cells (MFCs). However, little is known about the effect of membrane materials on the anodic microbial community diversity.; RESULTS: The effect of two cationic and one anionic exchange membranes (Nafion N-117, Ultrex CMI-7000, and Ultrex AMI-7000) on the microbial community dynamics of Eubacteria and Archaea has been assessed in two-chambered MFCs. The experimental results indicated that the eubacterial community in the anodic chamber was not affected by the membrane materials, being predominantly populations of Bacteroidetes (Porphyromonadaceae) and -proteobacteria (Alcaligenaceae and Comamonadaceae). On the other hand, the archaeal counterpart appears to be highly dependent on the type of membrane used, as was evidenced by the selective enrichment of Methanosarcina sp. in the MFC equipped with the membrane Nafion N-117 which was the MFC that showed the highest current production.; CONCLUSIONS: The results obtained in the present study suggest that membrane materials affect archaeal diversity whereas both anodofilic eubacteria and methanogenic archaea populations could play an important role in the overall MFC process performance.Peer ReviewedPostprint (author’s final draft
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