Patient Safety in Primary Health Care, Case Study of Cartaxo PrimaryCare Health Center

Worldwide we should achieve more efficient, clinically more effective and safer health care organizations, specially those in Primary Care (PC), where knowledge is less. For greater Patient Safety (PS) in PC Organizations, professionals are the key to ensure safety, with the involvement from Patient & Family. The goal is understand what Professionals Health Center Cartaxo Know and consequently incorporate PS in professional activity.What the PS know and consequently incorporate SD is little, it is carried out informally, not systematic, there is not enough information / training, much less routine routine of SD. Discrepancies in knowledge highlight crucial training vs information. The Cartaxo Health Center challenges are educational, structural and physical. Who integrates SD health care training (base / postgraduate, service) or Health Accreditation The knowledge about nature/impact and of adverse events is scarce (greater local reality than Primary Care) The Safety & Notification are not uniform, and used mainly in accredited units. The Safety Cultural is non-uniform in Functional Units (do not know differences). Is more difficult to notify about vacines at home. It is very important home context, family, informal caregivers.info:eu-repo/semantics/acceptedVersio

DomeView : a tool for digital planetariums

The content produced for fulldome projection is usually made in a frame (the master) with a format corresponding to a projection of the dome on a plane, commonly the fisheye projection. Due to the distortions involved, looking at the master does not give a clear idea of the final result once projectedon a planetarium dome. The common solution when creating and composing content is to go through an iterative process, making successive projections on a planetarium until the desired result is achieved. However, repeatedaccess to a planetarium is difficult, costly, and time consuming. So there is a need for an application that can provide theuser with a clear notion of the final result in the planetarium. In addition, if the application could be used to show content in a small (single projector) planetarium, like a portable one, its versatility would increase substantially. This paper reports on such an application: Domeview

Runoff at the micro-plot and slope scale following wildfire, central Portugal

Through their effects on soil properties and vegetation/litter cover, wildfires can strongly enhance overland flow generation and accelerate soil erosion [1] and, thereby, negatively affect land-use sustainability as well as downstream aquatic and flood zones. Wildfires are a common phenomenon in present-day Portugal, devastating in an average year some 100.000 ha of forest and woodlands and in an exceptional year like 2003 over 400.000 ha. There therefore exists a clear need in Portugal for a tool that can provide guidance to post-fire land management by predicting soil erosion risk, on the one hand, and, on the other, the mitigation effectiveness of soil conservation measures. Such a tool has recently been developed for the Western U.S.A. [3: ERMiT] but its suitability for Portuguese forests will need to be corroborated by field observations. Testing the suitability of existing erosion models in recently burned forest areas in Portugal is, in a nutshell, the aim of the EROSFIRE projects. In the first EROSFIRE project the emphasis was on the prediction of erosion at the scale of individual hill slopes. In the ongoing EROSFIRE-II project the spatial scope is extended to include the catchment scale, so that also the connectivity between hill slopes as well as channel and road processes are being addressed. Besides ERMiT, the principal models under evaluation for slope-scale erosion prediction are: (i) the variant of USLE [4] applied by the Portuguese Water Institute after the wildfires of 2003; (ii) the Morgan–Morgan–Finney model (MMF) [5]; (iii) MEFIDIS [6]. From these models, MEFIDIS and perhaps MMF will, after successful calibration at the slope scale, also be applied for predicting catchment-scale sediment yields of extreme events

Resposta parasitol?gicas e inflamat?ria de diferentes doses da Nitazoxanida na infec??o aguda em camundongos C57BL/6 infectados pela cepa Y do Trypanosoma cruzi.

Programa de P?s-Gradua??o em Ci?ncias Biol?gicas. N?cleo de Pesquisas em Ci?ncias Biol?gicas, Pr?-Reitoria de Pesquisa de P?s Gradua??o, Universidade Federal de Ouro Preto.Descoberta h? mais de 100 anos, a infec??o pelo Trypanossoma cruzi ainda demanda de uma estrat?gia terap?utica eficaz. O f?rmaco Benznidazol atua sobre o controle parasit?rio e regula??o da resposta imune em fase aguda, mas apresenta resultados insatisfat?rios em fase cr?nica com alta toxicidade e efeitos diversos, o que acarreta no abandono terap?utico. Por essa raz?o, novas estrat?gias farmacol?gicas t?m sido propostas visando a elimina??o dos parasitos e a regula??o da resposta inflamat?ria, elementos chaves para a patog?nese card?aca associada a este protozo?rio. Dentre as novas estrat?gias, destaca-se o f?rmaco Nitazoxanida (NTZ) com atividade anti-viral, anti-helm?ntica e anti-protozo?rio. Neste estudo, diferentes doses de NTZ (100, 200, 400, 600, 800, 1000 e 1200 mg / kg) foram administradas, via gavagem, durante 10 dias (12 em 12 horas) em camundongos C57BL/6 (n=9) infectados com 4.000 formas tripomastigotas do T. cruzi (cepa Y), al?m dos grupos: infectados n?o tratados e n?o infectados n?o tratados. A parasitemia foi realizada diariamente e, ap?s a eutan?sia (11? dia de infec??o), amostras de macerado card?aco e de plasma foram destinadas a an?lise de mediadores inflamat?rios (TNF, IL-10, IL-17 e CCL2) e bioqu?mica (TGO e TGP). Foi observado aumento no pico de parasitemia em todos os animais infectados e tratados com NTZ. N?o houve altera??o na massa card?aca ap?s o tratamento com NTZ, por?m observou-se 40% de mortalidade nos animais tratados com a dose de 1.200 mg/kg deste f?rmaco. A produ??o de TNF, CCL2 e IL-10 reduziu nos grupos tratados com NTZ em rela??o ao grupo n?o infectado e sem tratamento. Relativo ? produ??o de IL-17, houve redu??o nos animais tratados com NTZ em rela??o ao grupo infectado, por?m n?o tratado. N?o houve altera??o de TGP associada ? infec??o e ao tratamento, por?m detectou-se n?veis elevados de TGO com as doses de 800, 1000 e 1200 mg/kg de NTZ. Conclu?mos que doses menores de NTZ apresentaram regula??o parcial dos mediadores inflamat?rios (TNF, IL-10, IL-17 e CCL2) na fase aguda em camundongos infectados pelo T. cruzi com aumento no n?mero de parasitos circulantes.After more than 100 years of its discovery, until today, the Trypanosoma cruzi infection still demands an effective therapeutic strategy. The therapy with the Benznidazole shows effectiveness on T. cruzi control in the acute phase, however, it displays unsatisfactory results in chronic phase exhibiting high toxicity which leads to the therapy abandonment. New pharmacological approaches have been proposed aiming parasite eradication and, in parallel, the regulation of the inflammatory response since it is a key element of the cardiac pathogenesis related to this protozoan. Here, we highlight the anti-helmintic Nitazoxanide (NTZ) in a different dose (100, 200, 400, 600, 800, 1000 and 1200 mg / kg) administered by gavage for 10 days (12 to12 hours) in C57BL/ 6 mice (n = 9) infected with 4,000 trypomastigote forms of T. cruzi (Y strain). The parasitemia was performed daily and after euthanasia (11th day post infection), the plasma and heart homogenate were used for the liver enzymes TGO and TGP assays and for ELISA (TNF, IL-10, IL-17 and CCL2). An increase circulating parasites were observed in all infected NTZ-treated animals, but no changes were observed with the relative heart mass. However, 40% mortality was observed in the animals receiving 1200 mg/kg dose of this drug. The production of inflammatory mediators (TNF, CCL2 and IL-10) reduced in the NTZ-treated-groups, when compared to the uninfected/untreated animals. Regarding the production of IL-17, its reduction was observed with the NTZ-treated animals in comparison to the infected control. No change was observed with the TGP associated with the infection and treatments, but higher TGO levels were detected at the doses of 800, 1000 and 1200 mg/kg of NTZ. We conclude that the lower doses of NTZ showed partial regulation of the inflammatory mediators (TNF, IL-10, IL-17 and CCL2) in the acute phase of T. cruzi-infected C57BL/6 mice with an increase in the number of circulating parasites

Runoff and erosion at the micro-plot and slope scale in a small burnt catchment, central Portugal

Wildfires can have important impacts on hydrological processes and soil erosion in forest catchments, due to the destruction of vegetation cover and changes to soil properties. However, the processes involved are non-linear and not fully understood. This has severely limited the understanding on the impacts of wildfires, especially in the up-scaling from hillslopes to catchments; in consequence, current models are poorly adapted for burnt forest conditions. The objective of this presentation is to give an overview of the hydrological response and sediment yield from the micro-plot to slope scale, in the first year following a wildfire (2008/2009) that burnt an entire catchment nearby the Colmeal village, central Portugal. The overview will focus on three slopes inside the catchment, with samples including: • Runoff at micro-plot scale (12 bounded plots) and slope scale (12 open plots); • Sediments and Organic Matter loss at micro-plot scale (12 bounded plots) and slope scale (12 open plots plus 3 Sediment fences); • Rainfall and Soil moisture data; • Soil Water Repellency and Ground Cover data. The analysis of the first year following the wildfire clearly shows the complexity of runoff generation and the associated sediment transport in recently burnt areas, with pronounced differences between hillslopes and across spatial scales as well as with marked variations through time. This work was performed in the framework of the EROSFIRE-II project (PTDC/AGR-CFL/70968/2006) which has as overall aim to predict soil erosion risk in recently burnt forest areas, including common post-fire forest management practices; the project focuses on the simultaneous measurement of runoff and soil erosion at multiple spatial scales.The results to be presented in this session are expected to show how sediment is generated, transported and exported in the Colmeal watershed; and contribute to understand and simulate erosion processes in burnt catchments, including for model development and evaluation

A reforma do Altar cristão segundo o Concílio Vaticano II e a sua importância na disciplina de Educação Moral e Religiosa Católica : contributo para a unidade letiva “A Partilha do Pão” do 6.º ano do programa de Educação Moral e Religiosa Católica

O Altar cristão é para os crentes o local central para a expressão pessoal e comunitária da sua fé, nomeadamente, na Eucaristia. Ao mesmo tempo, permite uma aproximação entre o humano e o divino. É preciosa a perceção da importância do Altar por parte dos alunos e do seu real significado como local sagrado, de encontro com a alteridade, de partilha e de dádiva total de cada um. No contexto atual, a linguagem simbólica tem um papel fundamental na transmissão de uma mensagem e, por isso, o ensino de Educação Moral e Religiosa Católica não pode perder a oportunidade de dar a conhecer os símbolos da fé cristã. Sabemos que a cultura, a história e a identidade do mundo Ocidental tem as suas raízes na cultura cristã que não devemos esquecer. Por isso, conhecer o Altar e o que ele significa é mergulhar na nossa origem e identidade.The Cristian Altar is the focal point for personal and community expression of their faith for believers, namely, in the Eucharist. At the same time, it allows an approximation between the human and the divine. Students´ perception of the importance of the Altar and of its real meaning as a sacred place, where they can meet with otherness, share and give themselves away totally is paramount. In the current context, symbolic language plays a fundamental role in the transmission of a message and, therefore, the teaching of Catholic Moral and Religious Education should not miss out the opportunity to allow students know the Christian faith symbols. We know that Western world culture, history and identity have its roots in Christian culture, so we must not forget it. This is why knowing the Altar and what it means is to dive into our origin and identity

Inorganic Coordination Chemistry: Where We Stand in Cancer Treatment?

Metals have unique characteristics such as variable coordination modes, redox activity, and reactivity being indispensable for several biochemical processes in cells. Due to their reactivity, their concentration is tightly regulated inside the cells, and abnormal concentrations are associated with many disorders, such as cancer. As such metal complexes turned out to be very attractive as potential anticancer agents. The discovery of cisplatin was a crucial moment, which prompted the interest in Pt(II) and other metal complexes as potential anticancer agents. This chapter highlights the state of the art on metal complexes in cancer therapy, highlighting their uptake mechanisms, biological targets, toxicity, and drug resistance. Finally, based on the importance of selective target of cancer cells, drug delivery systems will also be discussed

Field oriented control of an axial flux permanent magnet synchronous motor for traction solutions

Electric Vehicles (EVs) are increasingly used nowadays, and different powertrain solutions can be adopted. This paper describes the control system of an axial flux Permanent Magnet Synchronous Motor (PMSM) for EVs powertrain. It is described the implemented Field Oriented Control (FOC) algorithm and the Space Vector Modulation (SVM) technique. Also, the mathematical model of the PMSM is presented. Both, simulation and experimental, results with different types of mechanical load are presented. The experimental results were obtained using a laboratory test bench. The obtained results are discussed.F CT – Fundação para a Ciência e Tecnologia in the scope of the project: PEst - OE/EEI/UI0319/201

Improving communication through a social project management approach - a car industry case study

This paper describes the results of a qualitative study for improving communication in New Product Development (NPD) projects through a social project management approach. Through a case study research strategy, the main communication problems in a Car Industry section, dealing with NPD projects, were identified and four important initiatives were established to solve these communication problems: (i) standardize an integrated project management process focused on social interaction; (ii) select the most appropriate information tools for an 'open' and continuous communication environment; (iii) standardize the information disclosure for each information tool; and (iv) create/improve the visualization of the disclosed information