124 research outputs found
Impact of the covid-19 pandemic on teacher quality of life: A longitudinal study from before and during the health crisis
Background: Prior to the COVID-19 pandemic, teachers were already reporting a low quality of life (QoL) perception, with a significant impact on mental and physical health due to various stress factors associated with work overload. The objective of this study was to evaluate the QoL impact on Chilean teachers before and during the COVID-19 pandemic. The analysis was performed following a longitudinal design on a sample of 63 Chilean teachers in pre-pandemic and COVID-19 pandemic timeframes. QoL perception, along with teachersā sociodemographic data, was evaluated via the Short-Form 36 Health Survey (SF-36) questionnaire. Sociodemographic variables presented no significant variations in pre-pandemic and pandemic comparisons. QoL, however, showed a significant decrease during the pandemic compared to the pre-pandemic measurement (p < 0.01). In each gender, there were significant differences between pre-pandemic and pandemic timeframes, with a greater impact among women in the mental and physical component summary variables and seven of the eight QoL scales (p < 0.01). Between age categories, people under 45 presented significant differences (p < 0.05) between pre-pandemic and pandemic timeframes in all summary dimensions and measurements. In conclusion, Chilean teachersā QoL perception has been affected by the COVID-19 pandemic. These findings could be related to work overload due to teleworking or feelings of uncertainty, loneliness, and fear that the pandemic and its associated confinements will worsen
The prediction of the operating conditions on the permeate flux and on protein aggregation during membrane processing of monoclonal antibodies
The lack of available material during early stage bioprocess development poses numerous processing challenges such as limiting the number of full-scale experiments. Extended fundamental process understanding could be gained with the use of an ultra scale-down (USD) device using as little as 1.7āÆmL per experimental run. The USD system is used to predict diafiltration and ultrafiltration/diafiltration (UF/DF) performance of a pilot-scale tangential flow filtration (TFF) system, fitted with a flat-sheet cassette, operating at 500-fold larger scale. Both systems were designed by maintaining a volumetric loading of 8.1āÆL of feed per m2. Permeate flux was predicted for monoclonal antibody solutions with the USD system across a range of transmembrane pressure drops, feed concentrations and flow conditions during diafiltration, and desired retentate concentrations during UF/DF operations. The resulting USD data were in good agreement with the pilot-scale TFF when scaled based on similar shear rates over the membrane surface. Little change in soluble aggregates was observed in both systems but there were significantly higher increases in product turbidity in the USD system. A correlation was established to relate turbidity increase based on the volume fraction of high shear stress zone for USD systems and various pilot-scale TFF systems. The correlation was extended to encompass the processing time and concentration for a wide range of membrane processing challenges in both scales
Concern about the spread of the invader seaweed Caulerpa taxifolia var. distichophylla (Chlorophyta: Caulerpales) towards the West Mediterranean
The new Australian alien seaweed Caulerpa taxifolia var. distichophylla, after being established along the Turkish Mediterranean coast in 2006, was recorded in Southern Sicily in 2007. Since then local fishermen claimed support to counteract the effects of entanglement of large amounts of the alien strain wrack in their trammel nets, causing the gear to become ineffective. The further northward and westward spread of the new alien strain is supposed to be limited by winter temperature. We present novel data confirming that the new alien strain is fully naturalized in Central Mediterranean and is expanding its range beyond such limit (i.e. the 15Ā°C February isotherm), thus becoming potentially able to colonize the western basin. By means of a preliminary estimation of effects on native polychaete assemblages, and considering some peculiarities of Sicily (mostly linked to its geographical position in the Mediterranean Sea), the risk linked to the increasing range of distribution of the invasive algae is highlighted
Sustainability check: a monitoring tool for the sustainability of rural water supplies
The UNICEF/WHO Joint Monitoring Programme (JMP) notes that 42% of the population of
Mozambique has access to safe water (UNICEF/WHO 2008). To accelerate access to water supply in the
rural areas, UNICEF is currently implementing a programme termed the One Million Initiative with
allocated funds from the Government of the Netherlands. To assess the sustainability of this programme,
UNICEF, in collaboration with government and non government partners, developed a programme
management tool termed a Sustainability Check. The check involves a selected number of control and
treatment communities which were selected based on a random statistical basis. A total of 52 water
supplies were assessed and then the sustainability in each community was tested using a multivariate
composite model tool. The results indicate low levels of sustainability of 50-75%.
Based on the
assessment, it is recommended to focus on spare parts provision and increased community capacity to
manage financial contributions for operation and maintenance of the water points
Technology and Livelihood Education Graduatesā Low Performance in the Licensure Examination for Teachers: A Phenomenological Study
Among the major areas in the Licensure Examination for Teachers (LET) in ahigher educational institution in CALABARZON area, Technology and LivelihoodEducation (TLE) ranks the lowest. This qualitative study explored reasons of TLEgraduatesā low performance. Using phenomenological design, four participantswere purposively sampled and interviewed one-on-one. Interview data weretranscribed and analyzed using Colaizziās method. Findings show that the reasonsleading to the participantsā low LET performance were: curriculum misalignment,inadequate facilities, unavailability of well-maintained laboratory tools,demotivation to study, lack of TLE faculty, long process for laboratory budget andrequisition, and misaligned faculty specialization. Participants gave suggestions onhow TEIs can adequately prepare TLE graduates for LET: aligning curriculumwith national standards, hiring of additional expert faculty, adequate provision offacilities, and further support for LET preparation. It can be concluded that lowLET performance is influenced by TEI curriculum and instruction. Mixed methodstudies may be conducted using these findings to investigate graduatesā TLEperformance nationwide
Successful treatment of granulomatous reactions secondary to injection of esthetic implants
In recent years, various injectable materials have come into use to
improve esthetic appearance. OBJECTIVE: We describe the clinical and
histopathologic aspects of two patients who received intradermal injections of an
unknown dermal filler and the different diagnostic tools used to identify the
unknown injected material (reflexion electron microscopy, electron dispersing
x-ray) and discuss the possibility of a metastatic granulomatous reaction in one
patient. We also describe two treatments for this complication and evaluate the
legal considerations of the use of materials that have been adulterated and/or
whose composition is unknown to the patient. METHODS: We present two patients who
developed a granulomatous foreign-body reaction after the subcutaneous injection
of an esthetic implant. We treated patient 1 with isotretinoin and 2 months later
with doxycycline. We administered isotretinoin to patient 2. RESULTS: We observed
a partial improvement in patient 1 after isotretinoin treatment and a remarkable
improvement after administration of doxycycline. In patient 2, we observed an
excellent response to isotretinoin. CONCLUSION: Isotretinoin and doxycycline,
when administered separately, seem to offer effective treatment for reactions
resulting from silicone implants. However, further studies that include a larger
number of patients and those with reactions secondary to other fillers are
clearly needed before the effectiveness of this treatment can be confirmed
Mainstreaming biodiversity: A review of national strategies
Biodiversity is suffering dramatic declines across the globe, threatening the ability of ecosystems to provide the services on which humanity depends. Mainstreaming biodiversity into the plans, strategies and policies of different economic sectors is key to reversing these declines. The importance of this mainstreaming is recognized by the Convention on Biological Diversity (CBD) and its Aichi targets. Individual countries can implement the goals of the CBD through their National Biodiversity Strategies and Action Plans (NBSAPs), which aim to, inter alia, support the mainstreaming of biodiversity into the policies of key economic sectors, such as agriculture, forestry and fisheries. This paper investigates the performance of countries at incorporating biodiversity mainstreaming into their post-2010 NBSAPs. We conduct a large-scale review of 144 NBSAPs against five criteria and calculate a national-level indicator for comparing levels of mainstreaming among countries. Our results show that developing countries, particularly those in Africa, have higher scores, indicating that they have a higher awareness of the importance of biodiversity mainstreaming. Developing nations were also more likely to involve a greater range of stakeholders in the NBSAP development process, whilst developed nations were less likely to give specific details about the monetary contributions of biodiversity to their economies. Overall, our findings suggest that biodiversity mainstreaming remains a challenge across much of the world, but that progress in some areas can provide direction and momentum in the future
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