Clinical impact of aging on outcomes of cardioneuroablation for reflex syncope or functional bradycardia. Results from the cardionEuroabLation: patiEnt selection, imaGe integrAtioN and outComEs. The ELEGANCE multicenter study

Background: Cardioneuroablation (CNA) is a novel treatment for reflex syncope. The effect of aging on CNA efficacy is not fully understood. Objective: We assessed the impact of aging on candidacy and efficacy of CNA for treating vasovagal syncope (VVS), carotid sinus syndrome (CSS) and functional bradyarrhythmia. Methods: The ELEGANCE multicenter study assessed CNA in patients with reflex syncope or severe functional bradyarrhythmia. Patients underwent pre-CNA Holter ECG, head-up tilt testing (HUT) and electrophysiologic study. CNA candidacy and efficacy was assessed in 14 young (18-40 years), 26 middle-aged (41-60 years) and 20 older (>60 years) patients. Results: Sixty patients (37 men; mean age: 51±16 years) underwent CNA. The majority (80%) had VVS, 8% CSS, and 12% functional bradycardia/AV block. Pre-CNA Holter ECG, HUT and EP findings did not differ across age groups. Acute CNA success was 93%, without differences between age groups (p=0.42). Post-CNA HUT response was negative in 53%, vasodepressor in 38%, cardioinhibitory in 7% and mixed in 2%, without differences across age groups (p=0.59). At follow-up (8 months, IQR:4-15), 53 (88%) patients were free of symptoms. Kaplan-Meier curves did not show differences in event-free survival between age groups (p=0.29). The negative predictive value of a negative HUT was 91.7%. Conclusions: CNA is a viable treatment for reflex syncope and functional bradyarrhythmia in all ages, and is highly effective in mixed VVS. HUT is a key-step of post-ablation clinical assessment

PERSPECTIVA PSICOSOCIAL DE LOS DERECHOS HUMANOS

Hoy en día es imprescindible abordar el problema de los derechos desde una perspectiva holística que integre la posición que el individuo ocupa en la sociedad y el impacto de los hechos sociales sobre su persona. Esta perspectiva va por lo tanto más allá del enfoque clásico de las violaciones a los derechos civiles y políticos de los ciudadanos sino, también incluye sus derechos económicos, sociales y culturales. Cualquier enfoque de tipo holístico debe entender al ser humano en su ambiente, social, cultural, natural y en función a todas las estructuras existentes, por más sutiles que sean o invisibles que parezcan. Precisamente este libro permite apreciar la dimensión amplia y compleja del ser en sociedad y las interacciones que de ambas partes se generan y las ramificaciones que producen. No es un ejercicio fácil y los editores de este volumen han logrado un salto cuántico al poder congregar en un solo espacio miradas que en otras circunstancias podrían haber sido opuestas y hasta contrarias a nuestra comprensión de problemas que, en efecto, tienen raíces comunes. El libro está dividido en 5 secciones, El espíritu de los tiempos actuales y los Derechos Humanos, Construcción ciudadana y ejercicio de los Derechos Humanos, Violaciones a Derechos Humanos, victimizaciones y su atención, Ejercicio de los Derechos Humanos y situaciones disruptivas y Defensa y defensores de Derechos Humanos.Manuel Gutiérrez Romero Jessica Ruiz Magañ

1er. Coloquio de educación para el diseño en la sociedad 5.0

Las memorias del 1er. Coloquio de Educación para el Diseño en la Sociedad 5.0 debenser entendidas como un esfuerzo colectivo de la comunidad de académicos de la División de Ciencias y Artes para el Diseño, que pone de manifiesto los retos y oportunidades que enfrenta la educación en diseño en un contexto de cambio acelerado y rompimiento de paradigmas.El evento se realizó el pasado mes de mayo de 2018 y se recibieron más de 50 ponencias por parte de las profesoras y profesores de la División.Las experiencias y/o propuestas innovadoras en cuanto a procesos de enseñanza y aprendizaje que presentan los autores en cada uno de sus textos son una invitación a reflexionar sobre nuestra situación actual en la materia, y emprender acciones en la División para continuar brindando una educación de calidad en diseño a nuestras alumnas, alumnos y la sociedad.Adicionalmente, se organizaron tres conferencias magistrales sobre la situación actual de la educación en Diseño y de las Instituciones de Educación Superior, impartidas por el Mtro. Luis Sarale, profesor de la Universidad Nacional de Cuyo en Mendoza (Argentina), y Presidente en su momento, de la Red de Carreras de Diseño en Universidades Públicas Latinoamericanas (DISUR), el Dr. Romualdo López Zárate, Rector de la Unidad Azcapotzalco, así como del Mtro. Luis Antonio Rivera Díaz, Jefe de Departamento de Teoría y Procesos del Diseño de la División de la Ciencias de la Comunicación y Diseño, en la Unidad Cuajimalpa de nuestra institución.La publicación de estas memorias son un esfuerzo divisional, organizado desde la Coordinación de Docencia Divisional y la Coordinación de Tecnologías del Aprendizaje, del Conocimiento y la Comunicación, para contribuir a los objetivos planteados en el documento ACCIONES:Agenda CyAD2021, en particular al eje de Innovación Educativa. Es necesario impulsar a todos los niveles de la División espacios de discusión orientados a reflexionar sobre el presente y futuro en la educación del diseñador, que contribuya a mejorar la calidad de la docencia y favorezca al fortalecimiento de los procesos de enseñanza y aprendizaje.Finalmente, extiendo un amplio reconocimiento a todos los miembros de la División que hicieron posible este evento, así como a todos los ponentes y participantes por compartir su conocimiento para que la División sea cada día mejor

Partially Saturated Vertical Constructed Wetlands and Free-Flow Vertical Constructed Wetlands for Pilot-Scale Municipal/Swine Wastewater Treatment Using Heliconia latispatha

Partially saturated vertical constructed wetlands (PSV-CWs) and free-flow vertical constructed wetlands (FFV-CWS) are treatment systems for which there is limited information on their operation in tropical climates and even scarcer information on their use for municipal/swine wastewater treatment. In this work, the removal of pollutants from municipal wastewater mixed with swine effluents was evaluated using PSV-CWs and FFV-CWs, at pilot scale, with the presence and absence of vegetation in a tropical climate. Six vertical flow CWs made up of polyvinyl chloride (1 m high and 0.5 m in diameter) were used; three were operated with free-flow conditions and three with partially saturated conditions. In each type of configuration, two reactors were planted with an individual of Heliconia latispatha, and one remained without vegetation. They were fed with municipal wastewater mixed with 50% of swine wastewater. Their ability to remove COD, TSS, TP, TN, N-NH4, and N-NO3 and plant development were evaluated. Heliconia latispatha registered better results of adaptation and vegetative development in the PSV-CWs in comparison with FFV-CWs measured as total biomass (5697.1 g/m2 and 5095.7 g/m2, respectively). PSV-CWs were slightly better for TSS elimination (4.21%), while FFV-CWs presented a better performance for TN removal (3.76%), N-NH4 (3.94%) and N-NO3 (4.76%) in the systems with vegetation; no significant difference (p ˃ 0.05) was found between the two types of CWs for the removal of COD and TP. However, significant differences (p ˂ 0.05) were found between the systems with vegetation and those without vegetation in both configurations. These results demonstrate that PSV-CWs represent a better option for the treatment of municipal/swine wastewater since their efficiency was slightly higher than, or similar to that of, FFV-CWs and allowed a better development of H. latispatha

Fauna y microflora edáfica asociada a diferentes usos de suelo

In order to evaluate the effects of land use with sugarcane and grasses on macrofauna, mesofauna and microflora in the municipality of Úrsulo Galván, Veracruz, we compared the abundance, richness and diversity of groups of organisms in soil with sugarcane, grass and native vegetation typical of the region. Soil samples were taken from a 25 x 25 cm quadrant at a depth of 0-30 cm, from which soil fauna and microflora were extracted to identify and quantify them. Results indicate that soil with sugarcane was less harmful to soil fauna (9 taxa and 305 individuals) than soil with grass (6 taxa and 91 individuals) and that it was not statistically different from soil with native vegetation (9 taxa and 357 individuals). The abundance of most of the macro and mesofauna groups corresponded to soil with native vegetation (Aranea, Formicidae, Diplopoda and Oligochaeta) and with sugarcane (Isoptera, Chilopoda y Diplura). In the dry season, soil with sugarcane recorded the highest abundance of phosphorus-solubilizing and nitrogen-fixing bacteria (12333 cfu and 9465 cfu, respectively) compared to soil with native vegetation (4840 cfc and 5774 cfu, respectively). Only the soil covered with sugarcane has no effect on the soil’s microbial flora and fauna.Con el objetivo de evaluar los efectos del uso de suelo con caña de azúcar y pastos, sobre la macrofauna, mesofauna y microflora en el municipio de Úrsulo Galván, Veracruz, se comparó la abundancia, riqueza y diversidad de grupos de organismos en suelo con caña, pasto y vegetación nativa típica de la región.Se utilizaron muestras de suelo tomadas con un cuadrante de 25 x 25 cm a profundidad de 0-30 cm, de los que se extrajo la fauna y microflora edáfica, para identificarla y cuantificarla. Los resultados indican que el suelo con caña de azúcar fue menos nocivo para la fauna edáfica (9 taxones y 305 individuos) que el suelo con pasto (6 taxones y 91 individuos) y que no fue diferente estadísticamente con el suelo con vegetación nativa (9 taxones y 357 individuos). La abundancia de la mayoría de los grupos de macro y mesofauna correspondieron a suelo con vegetación nativa (Aranea, Formicidae, Diplopoda y Oligochaeta) y con caña de azúcar (Isoptera, Chilopoda y Diplura). En la época de secas, el suelo con caña de azúcar registró la mayor abundancia de bacterias solubilizadoras de fósforo y fijadoras de nitrógeno (12333 ufc y 9465 ufc, respectivamente) en comparación con el suelo con vegetación nativa (4840 ufc y 5774 ufc, respectivamente). Únicamente el suelo cubierto con caña de azúcar tiene nula afectación sobre la fauna y flora microbiana del suelo

Partially Saturated Vertical Constructed Wetlands and Free-Flow Vertical Constructed Wetlands for Pilot-Scale Municipal/Swine Wastewater Treatment Using <i>Heliconia latispatha</i>

Partially saturated vertical constructed wetlands (PSV-CWs) and free-flow vertical constructed wetlands (FFV-CWS) are treatment systems for which there is limited information on their operation in tropical climates and even scarcer information on their use for municipal/swine wastewater treatment. In this work, the removal of pollutants from municipal wastewater mixed with swine effluents was evaluated using PSV-CWs and FFV-CWs, at pilot scale, with the presence and absence of vegetation in a tropical climate. Six vertical flow CWs made up of polyvinyl chloride (1 m high and 0.5 m in diameter) were used; three were operated with free-flow conditions and three with partially saturated conditions. In each type of configuration, two reactors were planted with an individual of Heliconia latispatha, and one remained without vegetation. They were fed with municipal wastewater mixed with 50% of swine wastewater. Their ability to remove COD, TSS, TP, TN, N-NH4, and N-NO3 and plant development were evaluated. Heliconia latispatha registered better results of adaptation and vegetative development in the PSV-CWs in comparison with FFV-CWs measured as total biomass (5697.1 g/m2 and 5095.7 g/m2, respectively). PSV-CWs were slightly better for TSS elimination (4.21%), while FFV-CWs presented a better performance for TN removal (3.76%), N-NH4 (3.94%) and N-NO3 (4.76%) in the systems with vegetation; no significant difference (p ˃ 0.05) was found between the two types of CWs for the removal of COD and TP. However, significant differences (p ˂ 0.05) were found between the systems with vegetation and those without vegetation in both configurations. These results demonstrate that PSV-CWs represent a better option for the treatment of municipal/swine wastewater since their efficiency was slightly higher than, or similar to that of, FFV-CWs and allowed a better development of H. latispatha

Outcomes of cavotricuspid isthmus-dependent flutter ablation: randomized study comparing single vs. multiple catheter procedures-the SIMPLE study

Background Catheter ablation is recommended as first-line therapy for patients with symptomatic typical AFl. Although the conventional multi-catheter approach is the standard of care for cavotricuspid isthmus (CTI) ablation, a single-catheter approach was recently described as a feasible alternative. The present study sought to compare safety, efficacy, and efficiency of single vs. multi-catheter approach for atrial flutter (AFl) ablation.Methods In this randomized multi-center study, consecutive patients referred for AFl ablation (n = 253) were enrolled and randomized to multiple vs. single-catheter approach for CTI ablation. In the single-catheter arm, PR interval (PRI) on the surface ECG was used to prove CTI block. Procedural and follow-up data were collected and compared between the two arms.Results 128 and 125 patients were assigned to the single-catheter and to the multi-catheter arms, respectively. In the single-catheter arm, procedure time was significantly shorter (37 +/- 25 vs. 48 +/- 27 minutes, p = 0.002) and required less fluoroscopy time (430 +/- 461 vs. 712 +/- 628 seconds, p &lt; 0.001) and less radiofrequency time (428 +/- 316 vs. 643 +/- 519 seconds, p &lt; 0.001), achieving a higher first-pass CTI block rate (55 (45%) vs. 37 (31%), p = 0.044), compared with the multi-catheter arm. After a median follow-up of 12 months, 11 (4%) patients experienced AFl recurrences (5 (4%) in the single-catheter arm and 6 (5%) in the multi-catheter arm, p = 0.99). No differences were found in arrhythmia-free survival between arms (log-rank = 0.71).Conclusions The single-catheter approach for typical AFl ablation is not inferior to the conventional multiple-catheter approach, reducing procedure, fluoroscopy, and radiofrequency time.[GRAPHICS]