736 research outputs found
Bootstrapping confidence intervals for the change-point of time series
We study an AMOC time series model with an abrupt change in the mean and
dependent errors that fulfill certain mixing conditions. We obtain confidence
intervals for the unknown change-point via bootstrapping methods.
Precisely we use a block bootstrap of the estimated centered error sequence.
Then we reconstruct a sequence with a change in the mean using the same
estimators as before. The difference between the change-point estimator of the
resampled sequence and the one for the original sequence can be use as an
approximation of the difference between the real change-point and its
estimator. This enables us to construct confidence intervals using the
empirical distribution of the resampled time series.
A simulation study shows that the resampled confidence intervals are usually
closer to their target levels and at the same time smaller than the asymptotic
intervals.Comment: 25 pages, 25 figure
Educational poverty in a comparative perspective: theoretical and empirical implications
Lohmann H, Ferger F. Educational poverty in a comparative perspective: theoretical and empirical implications. SFB 882 Working Paper Series. Vol 26. Bielefeld: DFG Research Center (SFB) 882 From Heterogeneities to Inequalities; 2014
Random walks - a sequential approach
In this paper sequential monitoring schemes to detect nonparametric drifts
are studied for the random walk case. The procedure is based on a kernel
smoother. As a by-product we obtain the asymptotics of the Nadaraya-Watson
estimator and its as- sociated sequential partial sum process under
non-standard sampling. The asymptotic behavior differs substantially from the
stationary situation, if there is a unit root (random walk component). To
obtain meaningful asymptotic results we consider local nonpara- metric
alternatives for the drift component. It turns out that the rate of convergence
at which the drift vanishes determines whether the asymptotic properties of the
monitoring procedure are determined by a deterministic or random function.
Further, we provide a theoretical result about the optimal kernel for a given
alternative
FAUC 213, a highly selective dopamine D4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia
Rationale: 2-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213) is a highly selective antagonist at the dopamine D4 receptor subtype. It was designed as a derivative of two partial antagonists and has been proven to be a complete antagonist in mitogenesis assay. Objectives: In the present study, FAUC 213 was examined for antipsychotic properties in animal models of behavioural neurobiology and neurochemistry. Methods: Different concentrations of FAUC 213 were screened for effects on spontaneous, as well as amphetamine-induced, locomotor activity and apomorphine-induced prepulse disruption. The liability of causing extrapyramidal side effects was investigated in models of catalepsy and by high-performance liquid chromatography (HPLC) detection of dopamine turnover in several brain regions. The application schedule was validated, and the bioavailability of the compound determined, by means of a HPLC-pharmacokinetic study. Results: A significant effect in both the reduction of amphetamine-induced locomotor hyperactivity and the restoration of apomorphine-disrupted prepulse inhibition was found at 30mg/kg. This dose proved not to be high enough to induce catalepsy or to increase dopamine turnover in the dorsal striatum, nucleus accumbens and medial prefrontal cortex. The selective D4 antagonist FAUC 213, therefore, is not believed to mediate the above-mentioned effects via D2 receptor antagonism, but a partial involvement of 5-HT2- and α1-receptors cannot be ruled out at present. Conclusions: We have gathered evidence that FAUC 213 exhibits atypical antipsychotic characteristic
Supremal inequalities for convex M-estimators with applications to complete and quick convergence
We consider M-estimators and derive supremal-inequalities of exponential-or
polynomial type according as a boundedness- or a moment-condition is fulfilled.
This enables us to derive rates of r-complete convergence and also to show
r-qick convergence in the sense of Strasser.Comment: 24 page
Weak convergence of probability measures on hyperspaces with the upper Fell-topology
Let E be a locally compact second countable Hausdorff space and F the
pertaining family of all closed sets. We endow F respectively with the
Fell-topology, the upper Fell topology or the upper Vietoris-topology and
investigate weak convergence of probability measures on the corresponding
hyperspaces with a focus on the upper Fell topology. The results can be
transferred to distributional convergence of random closed sets in E with
applications to the asymptotic behavior of measurable selection
A continuous mapping theorem for the argmin-set functional with applications to convex stochastic processes
summary:For lower-semicontinuous and convex stochastic processes and nonnegative random variables we investigate the pertaining random sets of all -approximating minimizers of . It is shown that, if the finite dimensional distributions of the converge to some and if the converge in probability to some constant , then the converge in distribution to in the hyperspace of Vietoris. As a simple corollary we obtain an extension of several argmin-theorems in the literature. In particular, in contrast to these argmin-theorems we do not require that the limit process has a unique minimizing point. In the non-unique case the limit-distribution is replaced by a Choquet-capacity
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