A nation-wide laboratory: Examining trust and trustworthiness by integrating behavioral experiments into representative surveys

Typically, laboratory experiments suffer from homogeneous subject pools and selfselection biases. The usefulness of survey data is limited by measurement error and by the questionability of their behavioral relevance. Here we present a method integrating interactive experiments and representative surveys thereby overcoming crucial weaknesses of both approaches. One of the major advantages of our approach is that it allows for the integration of experiments, which require interaction among the participants, with a survey of non-interacting respondents in a smooth and inexpensive way. We illustrate the power of our approach with the analysis of trust and trustworthiness in Germany by combining representative survey data with representative behavioral data from a social dilemma experiment. We identify which survey questions intended to elicit peoples trust correlate well with behaviorally exhibited trust in the experiment. People above the age of 65, highly skilled workers and people living in bigger households exhibit less trusting behavior. Foreign citizens, Catholics and people favoring the Social Democratic Party or the Christian Democratic Party exhibit more trust. People above the age of 65 and those in good health behave more trustworthy or more altruistically, respectively. People below the age of 35, the unemployed and people who say they are in favor of none of the political parties behave less trustworthy or less altruistically, respectively. -- Die experimentelle Ökonomie führt typischerweise Labor-Untersuchungen durch, die mit homogenen und selektiven Versuchspersonen arbeiten. Repräsentative Surveys leiden hingegen unter Meßfehlern und der Frage, ob hypothetisches Verhalten, das erhoben wird, mit tatsächlichem Verhalten korrespondiert. Deswegen präsentieren wir eine Methode, mit der man die Schwächen beider Ansätze überwindet, indem man Survey-Daten mit Experimenten kombiniert. Die von uns entwickelte Methode hat den Vorzug, dass sie es auf preiswerte Art und Weise erlaubt, Experimente, die die Interaktion zweier Personen erfordern, mit Standard-Surveys zu kombinieren, die auf der Unabhängigkeit der befragten Personen beruhen. Wir illustrieren die Möglichkeiten unserer Methodik mit einer Untersuchung über Vertrauen und Vertrauenswürdigkeit in Deutschland, bei der eine repräsentative Umfrage mit einem Experiment über eine Dilemma-Situation verbunden wurde. Unsere Resultate zeigen zum einen, dass nicht alle Survey-Fragen über Vertrauen mit den Ergebnissen des Experiments korrelieren. Zum zweiten zeigen unsere Ergebnisse, dass ältere Menschen (65 Jahre und älter), Hochqualifizierte und Personen, die in grösseren Haushalten leben, im Experiment unterdurchschnittlich Vertrauen offenbaren. Für Ausländer, Katholiken und die Anhänger der großen Volksparteien finden wir überdurchschnittliches Vertrauen. Vertrauenswürdigkeit bzw. Altruismus zeigen im Experiment Ältere und Befragte mit gutem Gesundheitszustand. Unterdurchschnittliche Vertrauenswüdigkeit bzw. Altruismus zeigen jüngere Befragte (bis zu 35 Jahren), arbeitslos Gemeldete und Befragte ohne eine Parteineigung.Experiment,Survey,Trust,Trustworthiness,Altruism

Super-additive cooperation

Repeated interactions provide an evolutionary explanation for one-shot human cooperation that is counterintuitive but orthodox. Intergroup competition provides an explanation that is intuitive but heterodox. Here, using models and a behavioural experiment, we show that neither mechanism reliably supports cooperation. Ambiguous reciprocity, a class of strategies that is generally ignored in models of reciprocal altruism, undermines cooperation under repeated interactions. This finding challenges repeated interactions as an evolutionary explanation for cooperation in general, which further challenges the claim that repeated interactions in the past can explain one-shot cooperation in the present. Intergroup competitions also do not reliably support cooperation because groups quickly become extremely similar, which limits scope for group selection. Moreover, even if groups vary, group competitions may generate little group selection for multiple reasons. Cooperative groups, for example, may tend to compete against each other. Whereas repeated interactions and group competitions do not support cooperation by themselves, combining them triggers powerful synergies because group competitions constrain the corrosive effect of ambiguous reciprocity. Evolved strategies often consist of cooperative reciprocity with ingroup partners and uncooperative reciprocity with outgroup partners. Results from a behavioural experiment in Papua New Guinea fit exactly this pattern. They thus suggest neither an evolutionary history of repeated interactions without group competition nor a history of group competition without repeated interactions. Instead, our results suggest social motives that evolved under the joint influence of both mechanisms

Whitepaper - Augmented Helicopter Rescue Operation with Air2X and Virtual Infrastructure

This paper describes current operational procedures, circumstances and challenges of rescue helicopter landings on highways and is dedicated to present the technological solution of a communication interface between aerial and ground vehicles for increasing safety and efficiency. While a direct communication link between both sides would be the preferred option, this paper provides a solution that allows a near-term implementation and deployment. Consequently, a translating unit is required to merge the different expected communication standards of both domains. For the temporary establishment of a safe exclusive landing zone without ground support, the concept requires a low number of highly automated ground vehicles in a mixed traffic, guaranteeing a foreseeable behavior of certain traffic participants. Besides the technical implementation, safety, security and regulatory aspects of the concept are considered

Crucial Role of Interferon Consensus Sequence Binding Protein, but neither of Interferon Regulatory Factor 1 nor of Nitric Oxide Synthesis for Protection Against Murine Listeriosis

Listeria monocytogenes is widely used as a model to study immune responses against intracellular bacteria. It has been shown that neutrophils and macrophages play an important role to restrict bacterial replication in the early phase of primary infection in mice, and that the cytokines interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) are essential for protection. However, the involved signaling pathways and effector mechanisms are still poorly understood. This study investigated mouse strains deficient for the IFN-dependent transcription factors interferon consensus sequence binding protein (ICSBP), interferon regulatory factor (IRF)1 or 2 for their capacity to eliminate Listeria in vivo and in vitro and for production of inducible reactive nitrogen intermediates (RNI) or reactive oxygen intermediates (ROI) in macrophages. ICSBP−/− and to a lesser degree also IRF2−/− mice were highly susceptible to Listeria infection. This correlated with impaired elimination of Listeria from infected peritoneal macrophage (PEM) cultures stimulated with IFN-γ in vitro; in addition these cultures showed reduced and delayed oxidative burst upon IFN-γ stimulation, whereas nitric oxide production was normal. In contrast, mice deficient for IRF1 were not able to produce nitric oxide, but they efficiently controlled Listeria in vivo and in vitro. These results indicate that (a) the ICSBP/IRF2 complex is essential for IFN-γ–mediated protection against Listeria and that (b) ROI together with additional still unknown effector mechanisms may be responsible for the anti-Listeria activity of macrophages, whereas IRF1-induced RNI are not limiting

NY-BR-1 protein expression in breast carcinoma: a mammary gland differentiation antigen as target for cancer immunotherapy

NY-BR-1 is a recently identified differentiation antigen of the mammary gland. To use NY-BR-1 for T-cell-based immunotherapy, analysis of its co-expression with HLA class I antigens is required. In the present tissue microarray study, primary breast cancers (n=1,444), recurrences (n=88), lymph node (n=525) and distant metastases (n=91) were studied for NY-BR-1 expression using a novel monoclonal antibody. NY-BR-1 expression was compared with prognosis, estrogen receptor, HER2-status, EGFR and HLA class I antigen expression. NY-BR-1 was more frequently expressed in grade 1 (82%) than in grade 2 (69%) and grade 3 (46%) carcinomas (P<0.0001). Moreover, NY-BR-1 expression correlated directly with estrogen receptor expression (P<0.0001) and inversely correlated with HER2-status and EGFR expression (P<0.0001 for both). Considering high expression level of co-expression, 198/1,321 (15%) primary breast carcinomas and 4/65 (6%) distant metastases expressed NY-BR-1 and HLA class I, suggesting that active immunotherapy can be applied to about 10% of breast cancer patients. Survival analysis showed an association of NY-BR-1 expression with better patient outcome (P=0.015). No difference between NY-BR-1 expression of primary tumors and metastases could be found, indicating that the presence of NY-BR-1 in metastases can be deduced from their corresponding primary. Forty-three paired biopsies taken from patients before and after chemotherapy suggest that NY-BR-1 expression is not influenced by preceding chemotherapy (κ=0.89, P<0.0001). In summary, the co-expression of NY-BR-1 with HLA class I antigens and its expression in metastases without modification by chemotherapy suggest that NY-BR-1 targeted immunotherapy represents a viable strategy in addition to other targeted cancer drug therapies of breast cance

Choosy Moral Punishers

The punishment of social misconduct is a powerful mechanism for stabilizing high levels of cooperation among unrelated individuals. It is regularly assumed that humans have a universal disposition to punish social norm violators, which is sometimes labelled “universal structure of human morality” or “pure aversion to social betrayal”. Here we present evidence that, contrary to this hypothesis, the propensity to punish a moral norm violator varies among participants with different career trajectories. In anonymous real-life conditions, future teachers punished a talented but immoral young violinist: they voted against her in an important music competition when they had been informed of her previous blatant misconduct toward fellow violin students. In contrast, future police officers and high school students did not punish. This variation among socio-professional categories indicates that the punishment of norm violators is not entirely explained by an aversion to social betrayal. We suggest that context specificity plays an important role in normative behaviour; people seem inclined to enforce social norms only in situations that are familiar, relevant for their social category, and possibly strategically advantageous