96 research outputs found

    Study of the functional product’s protein compounds digestion features

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    The aim of the study was to investigate the transformation of meat product’s proteins from pig hearts and aortas during enzymatic hydrolysis in an in vitro model of the gastrointestinal tract. The model consisted of three phases simulating digestion processes: “oral cavity” phase (a-amylase, pH 7.0; 2 min), “stomach” phase (pork pepsin, pH 3.0; 120 min), “intestine” phase (pork pancreatin, pH 7.0; 130 min). The product was sequentially subjected to hydrolysis, at the end of each phase, samples were taken to determine the protein concentration (biuret method) and visualize the protein fractions (one-dimensional electrophoresis). A significant increase in protein concentration at the “stomach” phase was revealed by 3.2 times, and the absolute content by 4.6 times. At the “intestine” phase, a decrease in the number of peptide complexes with copper ions by 1.8 times, the absolute protein content by 8.5% was re‑ vealed. The noted tendency was confirmed by electrophoretic studies — at the stage, simulating digestion in the stomach, the prod‑ ucts of meat product’s proteins hydrolysis were visualized; at the “intestine” phase, a low expression of protein fractions in the range of more than 10 kDa is shown. The maximum hydrolysis of protein compounds at the “stomach” phase to poly- and oligopeptides was confirmed, continuing at the “intestine” stage with the accumulation of free amino acids. This methodology makes it possible to visualize the products of hydrolysis of proteins in a meat product at all stages of the model and to monitor changes in protein concentration in the system

    Comparison of machine learning methods for analysis of ulcerative colitis proteomic data

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    Ulcerative colitis is a chronic inflammatory disease of the gastrointestinal system, affecting adults and children. Its cause is unknown, and the knowledge of reliable biomarkers is limited, especially for children. That makes the search for new biomarkers and pushing forth the analysis of the available data particularly challenging. We investigate proteomic data from children patients as a promising source, and tackle the problem implementing the recently developed parenclitic network approach to machine learning algorithms that solve classification task for proteomic data from healthy and diseased. We expect our approach to be applicable to other gastrointestinal diseases

    TO THE QUESTION OF PREPARATION OF WORKERS IN THE CONDITIONS OF INDUSTRIAL PRODUCTION

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    В статье рассматриваются актуальность разработки содержательных компонентов подготовки рабочих в условиях промышленного производства, актуальность применения имитационных технологий обученияThe article discusses the relevance of the development of substantial components of the training of workers in industrial production, the relevance of the use of simulation training technologie

    Peculiarities of preparation of a vocational teacher for use of application software taking into account the requirements of the federal state education standard

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    The significance of the issue under study is due to the fact that nowadays there is a necessity of rethinking of conception of training future vocational teachers to use application software taking into account a competency-based approach. The article is aimed at studying the contradictions underscored while analyzing the conditions of the process of preparation of future vocational teachers for using application software within the educational process and also the ways of their solving realized with the help of the competency-based approach. The competency-based approach allows forming a system of requirements for the practical part of the research based on technology of project education. In the given research work the authors' viewing of principles of formation of conditions of preparation of the vocational teachers for using the application software within the education process is presented. The analysis of groups of conditions is made with regard to the discipline "Information Technologies in Education." With the use of traditional vision ("to know, to be able, to have") and vision from the point of view of Dublin descriptors. The contents of the article could be of interest for teachers who are engaged into training the Bachelors of Vocational Education (branch-wise) and also retraining in the sphere of use of the application software in the education process. © Authors

    Искусственный интеллект как средство создания музыки

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    Творчество, в частности музыкальное – это набор алгоритмов и шаблонов. Ученые постоянно предпринимают попытки разработать тот самый алгоритм творчества, который научил бы искусственный интеллект создавать музыкальные композиции, подобно людям. Статья посвящена рассмотрению двух подходов к созданию музыкальных композиций, которые довольно востребованы для решения подобных задач.Creativity, in particular in music, is a set of algorithms and patterns. Scientists are constantly trying to develop the algorithm of creativity that would teach artificial intelligence to create musical compositions as well as people do. This article is devoted to the consideration of two approaches to the creation of musical compositions, which are quite common for problems of this kind

    Characterization of nonlinear effects in edge filters

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    A specially designed and produced edge filter with pronounced nonlinear effects is carefully characterized. The nonlinear effects are estimated at the intensities close to the laser-induced damage.Comment: 3 page

    Water Resources Management In Support Of Raw Region Based On Decoupling Effect

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    It determines the presence of the decoupling effect in the Russians raw regions materials by using water. Developed models that explain the relationship between the gross regional product and water intake. It proved no effect on the growth of water consumption in most regions of the reference commodity. Recommendations for the decoupling effect development in support of Russians raw regions

    Organizational and economic transformations towards the greening of agro-industrial production

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    The increase in the production of agricultural products and food supplies in excess of regulatory needs and the provision of food safety in Russia led to the expansion of the export of agricultural products and the change in the course of the development of the agro-industrial complex from import substitution to export-oriented production. However, the entry to world food markets requires high quality of products from manufacturers and its certification in accordance with world standards. The article presents the organizational and economic transformations towards the greening of agro-industrial production, namely, the use of the resource potential, the involvement of Russian manufacturers in the production of environmentally friendly products and the development of organic agriculture; the mechanisms for solving the set problems are substantiated.peer-reviewe

    Development of creative abilities of students of vocational pedagogical higher education in the formation of information competences

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    Рассматривается возможность развития творческих способностей студентов профессионально-педагогического вуза через внедрение специальных профессионально направленных заданийThe article describes the possibility of development of creative abilities of students of professional pedagogical high school through introduction of special professionally directed assignment
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