74 research outputs found
El régimen de separación personal en el nuevo artículo 203 del Código Civil
Fil: Burgos Baronda, María Cecilia. Universidad de Buenos Aires. Facultad de Derecho. Cátedra Derecho de Familia y Sucesiones. Buenos Aires, Argentin
Exact "hydrophobicity" in deterministic circuits: dynamical fluctuations in the Floquet-East model
We study the dynamics of a classical circuit corresponding to a discrete-time
deterministic kinetically constrained East model. We show that -- despite being
deterministic -- this "Floquet-East" model displays pre-transition behaviour,
which is a dynamical equivalent of the hydrophobic effect in water. By means of
exact calculations we prove: (i) a change in scaling with size in the
probability of inactive space-time regions (akin to the "energy-entropy"
crossover of the solvation free energy in water), (ii) a first-order phase
transition in the dynamical large deviations, (iii) the existence of the
optimal geometry for local phase separation to accommodate space-time solutes,
and (iv) a dynamical analog of "hydrophobic collapse". We discuss implications
of these exact results for circuit dynamics more generally.Comment: 15 pages, 5 figure
Exact Quench Dynamics of the Floquet Quantum East Model at the Deterministic Point
We study the nonequilibrium dynamics of the Floquet quantum East model (a Trotterized version of the kinetically constrained quantum East spin chain) at its "deterministic point,"where evolution is defined in terms of CNOT permutation gates. We solve exactly the thermalization dynamics for a broad class of initial product states by means of "space evolution."We prove: (i) the entanglement of a block of spins grows at most at one-half the maximal speed allowed by locality (i.e., half the speed of dual-unitary circuits); (ii) if the block of spins is initially prepared in a classical configuration, speed of entanglement is a quarter of the maximum; (iii) thermalization to the infinite temperature state is reached exactly in a time that scales with the size of the block.</p
meningococcal c conjugate vaccine effectiveness before and during an outbreak of invasive meningococcal disease due to neisseria meningitidis serogroup c cc11 tuscany italy
Abstract Introduction In Tuscany, Italy, where a universal immunization program with monovalent meningococcal C conjugate vaccine (MCC) was introduced in 2005, an outbreak of invasive meningococcal disease (IMD) due to the hypervirulent strain of Neisseria meningitidis C/cc11 occurred in 2015–2016, leading to an immunization reactive campaign using either the tetravalent (ACWY) meningococcal conjugate or the MCC vaccine. During the outbreak, IMD serogroup C (MenC) cases were also reported among vaccinated individuals. This study aimed to characterize meningococcal C conjugate vaccines (MenC-vaccines) failures and to estimate their effectiveness since the introduction (2005–2016) and during the outbreak (2015–2016). Methods MenC cases and related vaccine-failures were drawn from the National Surveillance System of Invasive Bacterial Disease (IBD) for the period 2006–2016. A retrospective cohort-study, including the Tuscany' population of the birth-cohorts 1994–2014, was carried out. Based on annual reports of vaccination, person-years of MenC-vaccines exposed and unexposed individuals were calculated by calendar-year, birth-cohort, and local health unit. Adjusted (by birth-cohort, local health unit, and calendar-year) risk-ratios (ARR) of MenC invasive disease for vaccinated vs unvaccinated were estimated by the Poisson model. Vaccine-effectiveness (VE) was estimated as: VE = 1-ARR. Results In the period 2006–2016, 85 MenC-invasive disease cases were reported; 61 (71.8%) from 2015 to 2016. Twelve vaccine failures occurred, all of them during the outbreak. The time-interval from immunization to IMD onset was 20 days in one case, from 9 months to 3 years in six cases, and ≥7 years in five cases. VE was, 100% (95%CI not estimable, p = 0.03) before the outbreak (2006–2014) and 77% (95%CI 36–92, p Conclusions In Tuscany, MenC-vaccine failures occurred exclusively during the 2015–2016 outbreak. Most of them occurred several years after vaccination. VE during the outbreak-period was rather high supporting an effective protection induced by MenC-vaccines
Cluster of invasive Neisseria meningitidis infections on a cruise ship, Italy, October 2012.
We describe a cluster of four cases of invasive meningococcal disease that occurred on a cruise ship sailing along the Italian coast in October 2012. All four cases were hospitalised with severe illness and one of them died. This report illustrates the importance of rapid implementation of emergency control measures such as administration of prophylaxis to all crew members and passengers to prevent the spread of the disease in such a close environment
Twenty years of surveillance of Invasive Meningococcal Diseases in Puglia, Italy
The study aims to investigate the change in the burden of disease and the microbiological characteristics of Invasive Meningococcal Disease (IMD) in Puglia in comparison with overall incidence from 1994 through 2014
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