Systemic Syndrome

Pages 45-4

Topiramate in the treatment of partial and generalized epilepsy

Topiramate (TPM) is a widely-used drug for the treatment of epilepsy. It is useful for several types of partial-onset and generalized-onset seizures, and is therefore considered a broad-spectrum agent. It is also effective as a prophylactic against migraine headaches. TPM was first approved for prescription use in 1996. In various countries it is now approved for adjunctive and monotherapy of partial-onset seizures and for therapy of generalized tonic-clonic seizures of nonfocal origin, for children and adults. For initial monotherapy of new-onset seizures, a target dose of 100 mg/day for adults is recommended. Adjunctive use with enzyme-inducing drugs and use for refractory seizures requires higher dosages, though the optimum dose for most patients does not exceed 400 mg/day. Excretion is primarily renal and TPM is not a significant hepatic enzyme inducer. Although it is usually safe and well-tolerated, adverse effects limit use in about 25% of patients. The most salient of these is cognitive dysfunction, especially problems with expressive speech and verbal memory. Weight loss, renal stones, paresthesias and other central nervous system side effects may occur. Tolerability is improved by low initial doses and slow titration to effect

Sustainable Messaging in Film: A Survey of a College Community

The concept of sustainability encompasses environmental, social, and economic issues. A sustainable approach encourages a balanced earth in both well-being and resource conservation for the sake of future generations. Unfortunately, awareness of and participation in various dimension of sustainability are currently inadequate given the current projections of the negative impact of climate change to humanity. Therefore, this project was designed to research if there was a relationship between viewing sustainably themed films and becoming more sustainably-conscious as a way to explore a potential avenue for mental and behavioral change. Furthermore, this project examines audience perception of sustainable messaging and content across various film genres in order to investigate sustainable community practices on a college campus, and participant’s level of interaction with sustainability. This research design draws on similar studies on film’s influence on behavior (Zillman and Weaver, 1999), current perceptions and practices of sustainability on college campuses (Stafford, 2011), and the use of mass media to promote sustainable behavior (Minton et al., 2012). Data was collected from primarily college-age students, utilizing pre-screening and post-screening surveys, which were designed to elicit perceptions of sustainability (generally) and sustainable messaging in film content. Additional contextual data was collected during post-screening discussions. The result of this study suggests that there was an immediate change in viewers’ perceptions from the pre-screening survey to the post-screening survey. Viewers agreed that their definition of sustainability had changed post-viewing

Their Old Kentucky Home: The Phenomenon of the Kentucky Burden in the Writing of James Still, Jesse Stuart, Allen Tate, and Robert Penn Warren

The focus of this project is to investigate the phenomenon of the Kentucky burden, and to explore the impact of that burden on four Vanderbilt-educated Kentucky authors of the early twentieth century. The works of James Still, Jesse Stuart, Allen Tate, and Robert Penn Warren reveal not only characteristics common to Southern regionalism in general but also traits radically particular to Kentucky. Through an exploration of the poetry and prose of these prominent Kentucky writers, we can gain a better understanding of the significance of their identities as Kentuckians and recognize the many obstacles and challenges the Kentucky burden posed for each of the four writers. I posit that the individual reactions of Still, Stuart, Tate, and Warren to the Kentucky burden dramatically affected their critical and popular success, thus deciding their place, or lack thereof, in the canon of American literature. By investigating this phenomenon, this project enters the debate concerning the existence of subregions within regionalism and further emphasizes the importance of the literature of the individual regions of this country which make up the whole American literature

Economic Regulation and Public Investment in Transportation Facilities

AIR TRANSPORTATION now serves as a primary method of intrastate, interstate, and international carrier movement, offering speed and efficiency to both the individual consumer and the commercial shipper. While the particular subject to be pursued concerns the impact of governmental regulation upon air transportation, it is quite clear that air transportation does not exist in a vacuum, but rather is only one of the many methods of transportation currently available. As such, it occupies a position on the spectrum of the national transportation system together with each of the other transportation sectors. Governmental regulation of any one of these particular sectors, thus, necessarily has an effect upon all segments, including the profitability of routes, quantity of traffic, per capita cost, and competitive use characteristics. When one considers the impact of governmental regulation on air transportation, one must also consider the impact of governmental regulation of all modes of transportation, because the orderly development of inter-modal freight and passenger movement and containerization is important to an efficient, total transportation system concept. The key to balanced economic regulation of transportation in such an environment lies within the development of a national policy on all levels from which regulation may come and a rational balance of public investment in transportation facilities

A Survey of Moorish Marraige

Purpose of the survey. This is the psychological moment in Moorish history in which to examine the marriage customs of the country. With the advent of Moroccan Independence in 1956, Moroccan manners and customs entered a state of flux--combining the old traditions with new and modern ways of living. As a result, weddings may become simpler, and the marriage outlook may become more vest- ernized; but, the background for both institutions will remain rooted in the age-old traditions and beliefs. It is these we will discuss in this thesis. They may possibly disappear within our own lifetimes, and it is, therefore, of fundamental importance that these cultural traditions concerning marriage be preserved. To my knowledge there has been no other study of this subject made in America. Many tourists and students have published comprehensive works on Moorish life, and, of course, have discussed marriage within the framework of a total study. Only westermarck\u27s Marriage Ceremonies in Morocco has dealt with the subject of itself