3,556 research outputs found
Texturing of InP surfaces for device applications
A unique process for texturing InP (100) wafers by anisotropic etching was developed. The process produces irregular V-grooves on the surface, which reduce the surface reflectivity. The process does not require photolithography or masking. The etching characteristics depend on doping, with etching tending to proceed more rapidly on the more heavily doped samples. Reduced reflectivity surfaces formed using this process can be applied to solar cells, photodetectors, and other optoelectronic devices
Enhancing optical absorption in InP and GaAs utilizing profile etching
The current state of profile etching in GaAs and InP is summarized, including data on novel geometries attainable as a function of etchant temperature, composition, and rate; substrate orientation; carrier concentration; and oxide thickness between substrate and photoresist. V-grooved solar cells were manufactured with both GaAs and InP, and the improved optical absorption was demonstrated. Preferred parameters for various applications are listed and discussed
Emergence of Bulk CsCl Structure in (CsCl)nCs+ Cluster Ions
The emergence of CsCl bulk structure in (CsCl)nCs+ cluster ions is
investigated using a mixed quantum-mechanical/semiempirical theoretical
approach. We find that rhombic dodecahedral fragments (with bulk CsCl symmetry)
are more stable than rock-salt fragments after the completion of the fifth
rhombic dodecahedral atomic shell. From this size (n=184) on, a new set of
magic numbers should appear in the experimental mass spectra. We also propose
another experimental test for this transition, which explicitely involves the
electronic structure of the cluster. Finally, we perform more detailed
calculations in the size range n=31--33, where recent experimental
investigations have found indications of the presence of rhombic dodecahedral
(CsCl)32Cs+ isomers in the cluster beams.Comment: LaTeX file. 6 pages and 4 pictures. Accepted for publication in Phys.
Rev.
MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-κB pathway
Telomerase-targeted therapy for cancer has received great attention because telomerase is expressed in almost all cancer cells but is inactive in most normal somatic cells. This study was aimed to investigate the effects of telomerase inhibitor MST-312, a chemically modified derivative of epigallocatechin gallate (EGCG), on acute promyelocytic leukemia (APL) cells. Our results showed that MST-312 exerted a dose-dependent short-term cytotoxic effect on APL cells, with G2/M cell cycle arrest. Moreover, MST-312 induced apoptosis of APL cells in caspase-mediated manner. Telomeric repeat amplification protocol (TRAP) assay revealed significant reduction in telomerase activity of APL cells following short-term exposure to MST-312. Interestingly, MST-312-induced telomerase inhibition was coupled with suppression of NF-κB activity as evidenced by inhibition of IκBα phosphorylation and its degradation and decreased NF-κB DNA binding activity. In addition, gene expression analysis showed downregulation of genes regulated by NF-κB, such as antiapoptotic (survivin, Bcl-2, Mcl-1), proliferative (c-Myc), and telomerase-related (hTERT) genes. Importantly, MST-312 did not show any apoptotic effect in normal human peripheral blood mononuclear cells (PBMCs). In conclusion, our data suggest that dual inhibition of telomerase activity and NF-κB pathway by MST-312 represents a novel treatment strategy for APL. © 2015, International Society of Oncology and BioMarkers (ISOBM)
A Computationally Efficient Method for Calculation of Strand Eddy Current Losses in Electric Machines
In this paper, a fast finite element (FE)-based method for the calculation of eddy current losses in the stator windings of randomly wound electric machines with a focus on fractional slot concentrated winding (FSCW) permanent magnet (PM) machines will be presented. The method is particularly suitable for implementation in large-scale design optimization algorithms where a qualitative characterization of such losses at higher speeds is most beneficial for identification of the design solutions which exhibit the lowest overall losses including the ac losses in the stator windings. Unlike the common practice of assuming a constant slot fill factor, sf, for all the design variations, the maximum sf in the developed method is determined based on the individual slot structure/dimensions and strand wire specifications. Furthermore, in lieu of detailed modeling of the conductor strands in the initial FE model, which significantly adds to the complexity of the problem, an alternative rectangular coil modeling subject to a subsequent flux mapping technique for determination of the impinging flux on each individual strand is pursued. The research focus of the paper is placed on development of a computationally efficient technique for the ac winding loss derivation applicable in design-optimization, where both the electromagnetic and thermal machine behavior are accounted for. The analysis is supplemented with an investigation on the influence of the electrical loading on ac winging loss effects for a particular machine design, a subject which has received less attention in the literature. Experimental ac loss measurements on a 12-slot 10-pole stator assembly will be discussed to verify the existing trends in the simulation results
Computationally Efficient Strand Eddy Current Loss Calculation in Electric Machines
A fast finite element (FE) based method for the calculation of eddy current losses in the stator windings of randomly wound electric machines is presented in this paper. The method is particularly suitable for implementation in large-scale design optimization algorithms where a qualitative characterization of such losses at higher speeds is most beneficial for identification of the design solutions that exhibit the lowest overall losses including the ac losses in the stator windings. Unlike the common practice of assuming a constant slot fill factor s f for all the design variations, the maximum s f in the developed method is determined based on the individual slot structure/dimensions and strand wire specifications. Furthermore, in lieu of detailed modeling of the conductor strands in the initial FE model, which significantly adds to the complexity of the problem, an alternative rectangular coil modeling subject to a subsequent flux mapping technique for determination of the impinging flux on each individual strand is pursued. Rather than pursuing the precise estimation of ac conductor losses, the research focus of this paper is placed on the development of a computationally efficient technique for the derivation of strand eddy current losses applicable in design optimization, especially where both the electromagnetic and thermal machine behavior are accounted for. A fractional-slot concentrated winding permanent magnet synchronous machine is used for the purpose of this study due to the higher slot leakage flux and slot opening fringing flux of such machines, which are the major contributors to strand eddy current losses in the windings. The analysis is supplemented with an investigation on the influence of the electrical loading on ac winding loss effects for this machine design, a subject that has received less attention in the literature. Experimental ac loss measurements on a 12-slot 10-pole stator assembly will be discussed to verify the existing trends in the simulation result
- …