The Essential History of a Patient with Pearson Marrow, a Case Report

Pearson syndrome is a rare mitochondrial disorder confirmed by mt-DNA deletion which typically occurs in the first two years of life. That is to say children are at high fatal risk, most infants are marked with some common features especially anemia and pancreatitis, which results in death in early childhood. A 6-month-old Iranian female infant was presented with macrocytic anemia, required packed red blood cell transfusions. She also was affected by exocrine pancreatic dysfunction, in which she underwent Creon treatment.By first year of age she had experienced some severe metabolic crises intermittently. After hospitalized for some months she was expired unfortunately. In conclusion, Pearson syndrome, as a rare disease affects many organs, such as liver, kidney, pancreas, bone marrow, which led to anemia, failure to thrive, and multi organ failure. In such cases, a physician must consider and evaluate all possible damages, especially anemia and pancreatitis. We present a case of Pearson syndrome with anemiaKeywords: Mitochondrial disorders; Pearson syndrome; Pancreatitis; Acidosis; Infants

The relationship between intellectual capital and earnings predictability in the companies listed in Tehran stock exchange

In this paper the researchers examined the relationship between intellectual capital and the earnings predictability of companies listed in Tehran Stock Exchange. The study was carried out in a period of time, between the years 2007 to 2011 which involved 101 companies listed in the Stock Exchange of Tehran. Research hypotheses, consisted of two main hypotheses, the first of which also included three sub- hypotheses. Research variables included components of intellectual capital as an independent variable and earnings predictability as the dependent variable. Firm size is also considered as a moderator variable. In order to test the research hypotheses, the researchers collected the necessary information from various sources, the Pulic model was used for estimating the value of intellectual capital and the Francis model was used to assess the earnings predictability. To summarize the data, the variables were fed into the Excel and then were processed by means of Eviews7 software for testing the hypotheses. The method used in this study was panel data with fixed effects. The results of testing the research hypotheses indicated that there is a significant relationship between intellectual capital and earnings predictability companies listed in the Stock Exchange of Tehran. It also shows that firm size as a moderator variable, affects the relationship between intellectual capital and earnings predictability in this corporation

The relationship between intellectual capital and earnings predictability in the companies listed in Tehran stock exchange

In this paper the researchers examined the relationship between intellectual capital and the earnings predictability of companies listed in Tehran Stock Exchange. The study was carried out in a period of time, between the years 2007 to 2011 which involved 101 companies listed in the Stock Exchange of Tehran. Research hypotheses, consisted of two main hypotheses, the first of which also included three sub- hypotheses. Research variables included components of intellectual capital as an independent variable and earnings predictability as the dependent variable. Firm size is also considered as a moderator variable. In order to test the research hypotheses, the researchers collected the necessary information from various sources, the Pulic model was used for estimating the value of intellectual capital and the Francis model was used to assess the earnings predictability. To summarize the data, the variables were fed into the Excel and then were processed by means of Eviews7 software for testing the hypotheses. The method used in this study was panel data with fixed effects. The results of testing the research hypotheses indicated that there is a significant relationship between intellectual capital and earnings predictability companies listed in the Stock Exchange of Tehran. It also shows that firm size as a moderator variable, affects the relationship between intellectual capital and earnings predictability in this corporation

The relationship between intellectual capital and earnings predictability in the companies listed in Tehran stock exchange

In this paper the researchers examined the relationship between intellectual capital and the earnings predictability of companies listed in Tehran Stock Exchange. The study was carried out in a period of time, between the years 2007 to 2011 which involved 101 companies listed in the Stock Exchange of Tehran. Research hypotheses, consisted of two main hypotheses, the first of which also included three sub- hypotheses. Research variables included components of intellectual capital as an independent variable and earnings predictability as the dependent variable. Firm size is also considered as a moderator variable. In order to test the research hypotheses, the researchers collected the necessary information from various sources, the Pulic model was used for estimating the value of intellectual capital and the Francis model was used to assess the earnings predictability. To summarize the data, the variables were fed into the Excel and then were processed by means of Eviews7 software for testing the hypotheses. The method used in this study was panel data with fixed effects. The results of testing the research hypotheses indicated that there is a significant relationship between intellectual capital and earnings predictability companies listed in the Stock Exchange of Tehran. It also shows that firm size as a moderator variable, affects the relationship between intellectual capital and earnings predictability in this corporation

On multiplication fs-modules and dimension symmetry

In this paper, we first study $fs$-modules, i.e., modules with finitely many small submodules. We show that every $fs$-module with finite hollow dimension is Noetherian. Also, we prove that an $R$-module $M$ with finite Goldie dimension, is an $fs$-module if and only if $M = M_1 \oplus M_2$, where $M_1$ is semisimple and $M_2$ is an $fs$-module with $Soc(M_2) \ll M$. Then, we investigate multiplication $fs$-modules over commutative rings and show that $R$ is an $fs$-ring if and only if every multiplication $R$-module is an $fs$-module. In particular, we prove that the lattices of $R$-submodules of $M$ and $S$-submodules of $M$ are coincide, where $S=End_R(M)$. Consequently, $M_R$ and $_SM$ have the same dimension of Krull (Noetherian, Goldie and hollow). Further, we prove that for any self-generator multiplication module $M$, to be an $fs$-module as a right $R$-module and as a left $S$-module are equivalent

Detection of Exotoxins and Antimicrobial Susceptibility Pattern in Clinical Pseudomonas Aeruginosa Isolates

Background: Pseudomonas aeruginosa is a common opportunistic pathogen that causes nosocomial infection in immunocompromised patients. Among different virulence factors, the type III secretion system (TTSS) is an important agent in virulence and development of antimicrobial resistance in P. aeruginosa. Objectives: Previous studies have shown that production of type III secretion system proteins was correlated with increasing virulence and resistance to several antibiotics. In this study we determined the exotoxins genes (exoU and exoS) and pattern of antimicrobial susceptibility in clinical P. aeruginosa isolates. Methods: A total of 175 P. aeruginosa isolates were collected from patients hospitalized in educational hospitals of Shahrekord and Chamran hospital of Isfahan, Iran from April to December 2015. Antimicrobial susceptibility test was performed by disk diffusion test. The presence of exotoxins genes was detected using multiplex PCR of exoU and exoS genes. Results: The antibiotic resistance rate was higher than 70% to many antibiotics. The highest rate of resistance was related to Levofloxacin and Meropenem (155 (88.6%), 148 (84.6%)) respectively. The exoU gene was found in 75 (42.9%) isolates and 136 (77.7%) of the isolates carried the exoS. In addition, 36(20.6%) of the isolates carried the both of gens. A statistical significance was detected between the presence of exoU gene and resistance to pipracillin (P = 0.01). Conclusions: The result of this study was indicated a high resistance rate to the most antibiotic classes and a specific relationship between the virulence genotype and antimicrobial resistance especially more virulent genotype of exoU+ . In order to prevent the spread of more virulent strains in health care facilities, molecular methods alongside antimicrobial susceptibility tests is suggested

Relation of religious coping with occupational stress and quality of working life for midwives working in maternity hospitals in Zahedan, Iran

Background: The health care center is considered as one of the main sustainable health spheres of human communities, which have direct relationship with human health. It has critical duty of maintaining and restoring health to human society. This study was conducted to investigate the role of religious coping components on occupational stress and quality of midwives' lives.Methods: The study method was descriptive of correlation type and the population consisted of all midwives working in maternity hospitals in Zahedan, in 2014. Three questionnaires were used as data gathering tools including, the quality of working life, occupational stress and religious coping. Data was analyzed using descriptive statistical methods, Pearson correlation coefficient and stepwise regression.Results: Considering the results of Pearson correlation coefficient, there is a significant negative relationship between religious activism (r= -0.454) and occupational stress. Regression analysis also showed that the variability of religious activism explained 45% of variations of occupational stress. In accordance with Pearson correlation test, there is no significant relationship between religious coping components and the quality of life.Conclusions: In conclusion, it is necessary to teach midwives essential trainings to strengthen coping strategies and religious activism in order to reduce occupational stress

The consistency rate of causes of Death in different components of child mortality Surveillance System in hospitals affiliated with the Shahrekord University of Medical Sciences

Background and aims: Child mortality Surveillance System is Iranian children mortality database nationwide and internationally. The aim of this study was to investigate one of the the most important features of data quality, i.e. Accuracy, through examining the consistency rate between the underlying mortality causes registered in the software and those extracted from medical records among children. Methods: This descriptive, analytical study was performed by census and the medical files of all 104 children aged 1-59 months died between March 21, 2013 and September 22, 2015 in six hospitals affiliated with the Shahrekord University of Medical Sciences were studied. The data were gathered by a researcher-developed questionnaire under supervision of a pediatrician. To investigate the consistency rate of mortality causes, chi-square and Fisher's Exact test and Kappa coefficient in SPSS was used. Results: The consistency rate between the mortality causes registered in the software and the underlying mortality causes extracted from the medical Records, and death certificate was 0.60 and 0.57, respectively. These consistency rates are considered moderate. The consistency rate between the underlying mortality causes recorded in the death certificates and the medical files was derived 0.84, considered an optimal level of consistency. Conclusion: According to the findings, it is essential to develop certain interventions such as training and requiring operators to be adequately tactful for recording underlying mortality causes with reference to death certificates and medical files, hiring operators who are knowledgeable about the international protocols of selection of mortality cause or planning for use of the underlying causes registered in the encoding unit of the software, and enhancing the software and accuracy of information elements registered in the software

Comparison of the effect of polyethylene glycol 40 and fig syrups on the treatment of chronic functional constipation in children: A randomized clinical trial

Background and aims: None of the available constipation treatments for children are completely successful. Therefore, the present study aimed to evaluate the effect of the polyethylene glycol (PEG) solution 40 and fig syrup on the treatment of chronic constipation in children. Methods: In this double-blind clinical trial, 120 patients with chronic functional constipation were selected and divided into two groups. The first group received 5 mL of fig syrup without senna 3 times daily, and the second group took PEG 40 syrup at 1 mL/kg of body weight per day (the dose was adjustable according to the patient�s condition and need). At weeks 0, 2, 4, and 6, a checklist containing questions about children�s constipation was completed by the researcher, and the data were analyzed by SPSS version 24. Results: Changes in the frequency of abdominal pain at fourth times 0, 2, 4, and 6 weeks demonstrated statistically significant differences between the two groups (P=0.044), and it was significantly lower the in PEG group; however, the defecation was not statistically significant (P=0.902). After six weeks, the frequency of painful defecation, difficult defecation straining during defecation, and fear of defecation was significantly lower in the group given PEG syrup compared to the fig syrup-receiving group (P=0.001). Conclusion: Overall, PEG syrup was significantly effective in treating chronic functional constipation in children compared to the fig syrup

Reactivity of aminophenols in forming nitrogen-containing brown carbon from iron-catalyzed reactions

Nitrogen-containing organic carbon (NOC) in atmospheric particles is an important class of brown carbon (BrC). Redox active NOC like aminophenols received little attention in their ability to form BrC. Here we show that iron can catalyze dark oxidative oligomerization of o- and p-aminophenols under simulated aerosol and cloud conditions (pH 1–7, and ionic strength 0.01–1 M). Homogeneous aqueous phase reactions were conducted using soluble Fe(III), where particle growth/agglomeration were monitored using dynamic light scattering. Mass yield experiments of insoluble soot-like dark brown to black particles were as high as 40%. Hygroscopicity growth factors (κ) of these insoluble products under sub- and super-saturated conditions ranged from 0.4–0.6, higher than that of levoglucosan, a prominent proxy for biomass burning organic aerosol (BBOA). Soluble products analyzed using chromatography and mass spectrometry revealed the formation of ring coupling products of o- and p-aminophenols and their primary oxidation products. Heterogeneous reactions of aminophenol were also conducted using Arizona Test Dust (AZTD) under simulated aging conditions, and showed clear changes to optical properties, morphology, mixing state, and chemical composition. These results highlight the important role of iron redox chemistry in BrC formation under atmospherically relevant conditions