Corrigendum to “Correlation between clinical and laboratory parameters and early pregnancy loss in assisted reproductive technology cycles: A cross-sectional study” [Int J Reprod BioMed 2022; 20: 683-690]

The authors have been informed of an error that occurred on page 684 in which the number of participants should be replaced with 408 instead of 480. On behalf of the author, the publisher wishes to apologize for this error. The online version of article has been updated on 23 October 2022 and can be found at https://doi.org/10.18502/ijrm.v20i8.11757

Correlation between clinical and laboratory parameters and early pregnancy loss in assisted reproductive technology cycles: A cross-sectional study

Background: The miscarriage rate after pregnancy resulting from assisted reproductive technology (ART) is about 20%, roughly half of which is biochemical. The correlations between the number and quality of oocytes, estradiol level and early pregnancy loss have not been fully clarified. Objective: This study aimed to examine the clinical and laboratory parameter effects on early abortion in ART cycles. Materials and Methods: In this cross-sectional study, 408 women who were ART candidates and were referred to the Yazd Infertility and Research Center, Yazd, Iran during March 2017 to March 2020 participated. Women who had a fresh embryo transferred and who had a positive beta human chorionic gonadotropin serum test were included in the study. The Anti-Müllerian hormone (AMH) level, embryo quality, oocyte number, progesterone level, estradiol level, and maternal age were extracted from the medical records. Results: No significant difference was observed in the age, mean estradiol and progesterone levels on trigger day, number of MII oocytes, and embryo quality between the groups (p = 0.19, 0.42, 0.07, 0.34 and 0.20, respectively). No statistically significant difference was found between the 3 groups of AMH level (p = 0.20). After evaluation using logistic regression, the rate of negative clinical pregnancies was higher in the group with AMH < 1 ng/ml. However, this was not found to be statistically significant. Conclusion: We did not find any correlation between early abortion and AMH levels, embryo quality, oocyte number, progesterone level, estradiol level, or maternal age. Key words: Abortion, Pregnancy, Embryo transfer, Assisted reproductive techniques, Anti-Müllerian hormone

Removable Appliance For Oral Self-Mutilation In Lesch-Nyhan Syndrome. A Case Report

Objectives Lesch-Nyhan syndrome is a rare inherited disorder associated with self-harming behaviors, delayed mental and motor development, and disturbances such as dysarthria, choreoathetosis, and spasticity. Severe inflicted behaviors in Lesch-Nyhan syndrome often include chewing and biting of the lips or fingers, which often require management. Techniques to deal with these behaviors include using appliances that restrict the behavior or ultimately extracting the teeth. Case This case report presents a 6-year-old child with Lesch-Nyhan syndrome and self-mutilation. He had chronic wounds in his buccal mucosa due to severe biting. Two acrylic devices with anterior and posterior bite plates were designed for the maxillary and mandibular teeth. At the follow-up visits, the wounds had been healed, but due to shedding of the primary teeth, and poor patient cooperation, the appliance design was slightly changed. The design of the device used for the patient inspires similar devices for patients with self-mutilation behaviors. Conclusion Early diagnosis and management of patients suffering from self-injurious behaviors may improve oral health-related quality of life of these patients. Acrylic appliances seem to be effective to minimize injury and to enhance fast healing of oral lesions

Addition of intramuscular to vaginal progesterone for luteal phase support in fresh embryo transfer cycles: A cross-sectional study

Background: Luteal phase deficiency is common in assisted reproductive technology and is characterized by inadequate progesterone production. Various studies have shown that administration of progesterone in fresh embryo transfer cycles increases the rate of clinical pregnancy and live birth rate. Progesterone administration has variable types: oral, vaginal, oil-based intramuscular, and subcutaneous. Objective: This study aims to compare the effect of adding intramuscular progesterone to the vaginal progesterone for luteal phase support in the fresh embryo transfer cycle. Materials and Methods: This study reviewed the information related to 355 women who had a fresh embryo transfer between March 2020 and February 2021 at the Yazd Reproductive Sciences Institute, Yazd, Iran. The participants population were divided into 2 groups based on the type of luteal phase support regime: group I (n = 173) received 400 mg vaginal progesterone alone twice a day from the day of ovum pick up; and group II (n = 182) received 50 mg IM of progesterone in addition to vaginal progesterone 400 mg twice a day from the day of ovum pick up. Chemical and clinical pregnancy rates were compared between groups. Results: The basic characteristics of groups were statistically similar. The rates of chemical and clinical pregnancy were higher in the vaginal plus IM progesterone group than in the vaginal progesterone group. Moreover, chemical pregnancy showed a significant difference between the groups (p = 0.011). Conclusion: Our findings demonstrated that the addition of IM progesterone to the vaginal progesterone improves the chemical pregnancy rate in fresh embryo transfer. Key words: Luteal phase, Progesterone, Assisted reproductive technology, Embryo transfer

Applying GMDH artificial neural network to predict dynamic viscosity of an antimicrobial nanofluid

Objective (s): Artificial Neural Networks (ANN) are widely used for predicting systems’ behavior. GMDH is a type of ANNs which has remarkable ability in pattern recognition. The aim the current study is proposing a model to predict dynamic viscosity of silver/water nanofluid which can be used as antimicrobial fluid in several medical purposes.Materials and Methods: In order to have precise model, it is necessary to consider all influential factors. Temperature, concentration and size of nano particles are used as input variables of the model. In addition, GMDH artificial neural network is applied to design a proper model. Data for modeling are extracted from conducted experimental studies published in valuable journals. Results: The dynamic viscosity of Ag/water nanofluid is precisely modeled by using GMDH. The obtained values for R-squared is equal to 0.9996 which indicates perfect precision of the proposed model. In addition, the highest relative deviation for the model is 2.2%. Based on the values of these statistical criteria, the model is acceptable and very accurate. Conclusion: GMDH artificial neural network is reliable approach to predict dynamic viscosity of Ag/water nanofluid by using temperature, concentration and size of particles as input data

Anthropometric Analysis of Cephalofacial Dimensions in Kerman, Iran

The human body dimensions are affected by ecological, biological, geographical, racial, sex, and age factors. Craniofacial measurements can be considered to be one of the important tools for determination of the morphological characteristics of the head and face. In this study, which was conducted on Persian adolescents living in Kerman/Iran, different forms of head and face were determined for using in various aspects of medicine. The study was conducted on 732 participants including 366 males and 366 females in the age of 18-20-year-old. In addition to the height and weight of the participants, cephalofacial sizes of them were measured and then cephalic, facial, and brain indices were calculated. Among the cephalofacial sizes, cranial length and breadth, cranial circumference, prosopic length and prosopic breadth were significantly greater in males compared to females (P<0.005). Also, volume and weight of brain were significantly greater in male comparing to female participants (P<0.005). The predominant type of head was meso-cephal, and the predominant type of face was meso-prosopic in both sexes

A review on the applications of nanotechnology in orthodontics

Objective (s): Nanotechnology has gained importance in recent years due to its ability in the enhancement of materials properties and other specifications such as antimicrobial properties. Nano-sized materials have been applied in various fields of dentistry. Nanotechnology can be employed in orthodontics to enhance the quality of treatment. In the current study, a comprehensive review is carried out on the applications of nanotechnology in orthodontics. Materials and Methods: In the first step, various databases such as Scopus, Google Scholar and Pubmed were searched by using appropriate keywords for the present study. Afterwards, the related resources were selected to be reviewed. Finally, the key findings of the reviewed studies were represented and summarized. Results: Based on the reviewed researches, nanotechnology is applicable in various aspects of orthodontics. By using nanotechnology, improved properties in mechanical and medical specifications are achievable. For instance, by using nano coating in archwires, the friction force between components can be reduced and facilitate its motion. In addition, adding some types of nano particles to the composites resulted in improvement in tensile and shear bond strength. Antimicrobial properties of specific nano particles such as silver makes them favorable for reducing microorganisms in orthodontics treatment. Moreover, nanotechnology can be used in nano-identation test to assess the tools employed in orthodontics. Conclusion: nanotechnology can be broadly employed in orthodontics to achieve better treatment including improved strength of utilized materials, more accurate positioning and reduced microorganisms

Factors associated with pharmacological and psychotherapy treatments adherence in patients with borderline personality disorder

BackgroundBorderline personality disorder is a major mental illness characterized by sustained relationship instability, impulsive behavior, and intense affects. Adherence is a complex behavior, from minor refusals to abandonment of treatment, which can be affected by various factors. Therefore, the present study aimed to investigate the factors affecting pharmacological and psychotherapy adherence, patients' attitude toward medication, and assessing medication and treatment adherence in patients with borderline personality disorder referred to an outpatient referral clinic in Tehran, Iran.MethodsThe study was a cross-sectional study. The files of patients with borderline personality disorder referred to the outpatient clinic of the Tehran Psychiatric Institute were reviewed as the first step. Data were collected using the Drug Attitude Inventory-10 (DAI-10) questionnaire and a questionnaire to determine the attitude of patients toward pharmacological and psychotherapy treatment as well as therapeutic adherence. After collecting data, patients' therapeutic adherence was divided into poor, partial, and good compliance.ResultsNinety-four patients were involved in the study, and fifty-four were women. Findings of DAI showed that 54 (57.4%) participants had negative attitudes toward medication, while 38 (40.4%) participants showed a negative attitude toward psychotherapy treatment. Additionally, the percentage of patients with good psychotherapy adherence (44.7%) was higher than that of patients with good medication adherence (31.9%). The most common reasons for discontinuation of treatment were medication side effects (53.1%), dissatisfaction with the therapist (40.3%), and then fear of medication dependence (40%). Patients with higher education levels and a positive history of hospitalization in a psychiatric ward had better adherence to psychotherapy (P &lt; 0.05).ConclusionResults of the current study show that attitude toward psychotherapy is more favorable than pharmacotherapy among patients with BPD. The rationale may be that medications are mainly prescribed for comorbid conditions and do not have substantial effects on the BPD symptoms, resulting in low medication adherence

Improvement in Cardiac Function following Transplantation of Human Umbilical Cord Matrix-Derived Mesenchymal Cells

Objectives: Human umbilical cord mesenchymal cells (hUCM) can be easily obtained and processed in a laboratory. These cells may be considered as a suitable source in the repair of heart failure diseases. We, therefore, examined whether these cells may contribute to heart regeneration following an acute experimental myocardial infarction (MI). Methods: MI-induced animals received 5 ! 10 6 hUCM cells, 5 ! 10 6 5-azacytidine-treated cells (dhUCM), or PBS alone, subepicardially. A group of animals with MI and no other former intervention served as controls. dhUCM cells were assessed for F-actin, myogenin and troponin-I expression. Re-sults: dhUCM cells appeared as binucleated cells with extensive cytoplasmic processes. These differentiated cells were F-actin and myogenin positive. Thirty days after LAD ligation, left ventricular ejection fraction and the percentage of fractional shortening improved significantly in cell-receiving animals. In addition, the amount of scar tissue was significantly reduced in hUCM and dhUCM groups compared to MI group (p ! 0.05). These parameters were comparable between hUCM and dhUCM groups. Histopathological evaluations revealed that some engrafted cells adjacent to and remote from the MI area expressed troponin-I, F-actin and connexin43. Conclusion: These findings demonstrated the potential therapeutic use of either differentiated or undifferentiated hUCM cells in treatment of heart failure conditions