Burden of disease resulting from chronic mountain sickness among young Chinese male immigrants in Tibet

BACKGROUND: In young Chinese men of the highland immigrant population, chronic mountain sickness (CMS) is a major public health problem. The aim of this study was to measure the disease burden of CMS in this population. METHODS: We used disability-adjusted life years (DALYs) to estimate the disease burden of CMS. Disability weights were derived using the person trade-off methodology. CMS diagnoses, symptom severity, and individual characteristics were obtained from surveys collected in Tibet in 2009 and 2010. The DALYs of individual patients and the DALYs/1,000 were calculated. RESULTS: Disability weights were obtained for 21 CMS health stages. The results of the analyses of the two surveys were consistent with each other. At different altitudes, the CMS rates ranged from 2.1-37.4%; the individual DALYs of patients ranged from 0.13-0.33, and the DALYs/1,000 ranged from 3.60-52.78. The age, highland service years, blood pressure, heart rate, smoking rate, and proportion of the sample working in engineering or construction were significantly higher in the CMS group than in the non-CMS group (p < 0.05). These variables were also positively associated with the individual DALYs (p < 0.05). Among the symptoms, headaches caused the largest proportion of DALYs. CONCLUSION: The results show that CMS imposes a considerable burden on Chinese immigrants to Tibet. Immigrants with characteristics such as a higher residential altitude, more advanced age, longer highland service years, being a smoker, and working in engineering or construction were more likely to develop CMS and to increase the disease burden. Higher blood pressure and heart rate as a result of CMS were also positively associated with the disease burden. The authorities should pay attention to the highland disease burden and support the development and application of DALYs studies of CMS and other highland diseases

Promoting Sino-UK Collaboration on Developing Low Carbon and Sustainable Methodologies for Brownfields and Marginal Land Re-use in China

The authors are grateful to all partners of the SPF project which include a wide team of collaborators and advisors across China and UK for their useful discussions and contribution during the project. Ming Liu and Chris He (Department of Science, Technology & Innovation, British Consulate-General Guangzhou), Rongxia Liu and Xia Yang (Administrative Centre for China’s Agenda21), Kate Canning (Arup) and David Middleton (Department for Environment and Rural Affairs, UK) helped discussion and revision of the report. We acknowledge the financial support from the Foreign Common Office’s Prosperity Fund programme. We also are grateful to the contribution of the University of Brighton and the Land Trust who supported the PSRP case study development project and shared its findings with this project. This report is one of the outputs of the China Prosperity Strategic Programme Fund (SPF) on “Promoting Sino-UK collaboration on developing low carbon and sustainable methodologies for Brownfields and marginal land re-use in China” (project 16AG15)Rapid urbanisation and changes in land use resulting from industrial change has left a legacy of vast polluted industrial and commercial areas (also called brownfields) and marginal land areas. Recent evidence from the UK, EU and USA indicate that these land areas may have considerable potential for renewables production, for example from solar, wind or biomass. In parallel there are opportunities for carbon storage in rehabilitated soil, as well as substitution by the production of renewables. The UK is also leading the understanding in the wider parallel benefits that can be achieved from ecosystem services and public health benefits from improved provision of green space. These multiple services can be provided together, in synergy, from soft re-uses of post-industrial sites, and in this way the post-industrial regeneration areas in China should be seen as a major opportunity for new enterprise, society and the wider environment. The improving bankability of renewable energy projects, and the possibility of creating a voluntary carbon offset business, means that revenue streams may be sufficient to pay for ongoing land management over time as a profit generating activity. In terms of fastest benefit to UK PLC and China, the likelihood is that combination of renewable energies with “dual use” for habitat will provide both more readily commercial brownfield re-use opportunities for cities in China in the short term, and also create better carbon management opportunities, as well as a variety of wider sustainability benefits. Thus this type of re-uses will create a platform for rapid commercial exchange and development between Chinese and UK companies. Considering that China is preparing an action plan for managing soil pollution and remediation across the country estimated to be RMB 7tn which is equivalent to one-third of the national exchange reserves, this report on developing low carbon and sustainable methodologies for brownfields and marginal land re-use in China provides timely information that will support the decision making for sustainable remediation opportunities in China. The report is intended to serve as a tool and resource guide to stakeholders involved in land remediation willing to engage in sustainable remediation implementation for renewable energy and carbon management applications. It is intended to inform remediation stakeholders unfamiliar with sustainable remediation about the concept, practices, and available resources. The report capitalises on UK leadership positions on the sustainable rehabilitation of brownfields land (SURF-UK), the soft re-use of brownfields (e.g. for energy or amenity rather than buildings); effective end-use directed risk management for contaminated land, and sustainable remediation.Foreign Common Office’s Prosperity Fund programme SPF project 16AG1

Population level determinants of acute mountain sickness among young men: a retrospective study

<p>Abstract</p> <p>Background</p> <p>Many visitors, including military troops, who enter highland regions from low altitude areas may suffer from acute mountain sickness (AMS), which negatively impacts workable man-hours and increases healthcare costs. The aim of this study was to evaluate the population level risk factors and build a multivariate model, which might be applicable to reduce the effects of AMS on Chinese young men traveling to this region.</p> <p>Methods</p> <p>Chinese highland military medical records were used to obtain data of young men (n = 3727) who entered the Tibet plateau between the years of 2006-2009. The relationship between AMS and travel profile, demographic characteristics, and health behaviors were evaluated by logistic regression. Univariate logistic models estimated the crude odds ratio. The variables that showed significance in the univariate model were included in a multivariate model to derive adjusted odds ratios and build the final model. Data corresponding to odd and even years (2 subsets) were analyzed separately and used in a simple cross-validation.</p> <p>Results</p> <p>Univariate analysis indicated that travel profile, prophylactic use, ethnicity, and province of birth were all associated with AMS in both subsets. In multivariate analysis, young men who traveled from lower altitude (600-800 m <it>vs</it>. 1300-1500 m, adjusted odds ratio (AOR) = 1.32-1.44) to higher altitudes (4100-4300 m <it>vs</it>. 2900-3100 m, AOR = 3.94-4.12; 3600-3700 m <it>vs</it>. 2900-3100 m, AOR = 2.71-2.74) by air or rapid land transport for emergency mission deployment (emergency land deployment <it>vs</it>. normal land deployment, AOR = 2.08-2.11; normal air deployment <it>vs</it>. normal land deployment, AOR = 2.00-2.20; emergency air deployment <it>vs</it>. normal land deployment, AOR = 2.40-3.34) during the cold season (cold <it>vs</it>. warm, AOR = 1.25-1.28) are at great risk for developing AMS. Non-Tibetan male soldiers (Tibetan <it>vs</it>. Han, AOR = 0.03-0.08), born and raised in lower provinces (eastern <it>vs</it>. northwestern, AOR = 1.32-1.39), and deployed without prophylaxis (prophylactic drug <it>vs</it>. none, AOR = 0.75-0.76), also represented a population at significantly increased risk for AMS. The predicted model was built; the area under receiver operating characteristic curve was 0.703.</p> <p>Conclusion</p> <p>Before a group of young men first enter a high altitude area, it is important that a health service plan should be made referring to the group's travel profile and with respect to young men's ethnicity and province of birth. Low-cost Chinese traditional prophylactic drugs might have some effect on decreasing the risk of AMS, although this needs further verification.</p

China's soil and groundwater management challenges: Lessons from the UK's experience and opportunities for China

There are a number of specific opportunities for UK and China to work together on contaminated land management issues as China lacks comprehensive and systematic planning for sustainable risk based land management, encompassing both contaminated soil and groundwater and recycling and reuse of soil. It also lacks comprehensive risk assessment systems, structures to support risk management decision making, processes for verification of remediation outcome, systems for record keeping and preservation and integration of contamination issues into land use planning, along with procedures for ensuring effective health and safety considerations during remediation projects, and effective evaluation of costs versus benefits and overall sustainability. A consequence of the absence of these overarching frameworks has been that remediation takes place on an ad hoc basis. At a specific site management level, China lacks capabilities in site investigation and consequent risk assessment systems, in particular related to conceptual modelling and risk evaluation. There is also a lack of shared experience of practical deployment of remediation technologies in China, analogous to the situation before the establishment of the independent, non-profit organisation CL:AIRE (Contaminated Land: Applications In Real Environments) in 1999 in the UK. Many local technology developments are at lab-scale or pilot-scale stage without being widely put into use. Therefore, a shared endeavour is needed to promote the development of technically and scientifically sound land management as well as soil and human health protection to improve the sustainability of the rapid urbanisation in China

Hydrochemical Characteristics and Cause Analysis of Natural Water in the Southeast of Qinghai-Tibet Plateau

This study investigated the hydrochemical characteristics and formation mechanism of natural water in the southeastern Qinghai-Tibet Plateau. To this end, 19 groundwater samples were collected, tested, and analyzed using various methods, such as mathematical statistics, a Piper diagram, correlation analysis, Gibbs plots, and an ion ratio analysis. The results show that the dominant anions are HCO3&minus; and SO42&minus;, and the dominant cations are Ca2+ and Mg2+, which accounted for 98.50% and 85.94% of the total amount of anions and cations, respectively. The samples were weakly alkaline water, where the TDS (total dissolved solids) ranged from 28.00 mg/L to 242.00 mg/L, with an average value of 129.10 mg/L. The hydrochemical types were mainly Ca&middot;Mg-HCO3&middot;SO4&mdash;accounting for 42.10%. The hydrochemical evolution process was found to be mainly controlled by the weathering and dissolution of carbonate and silicate rocks. The main sources of Na+ and K+ are rock salt and silicate rocks, and those of Ca2+, Mg2+, HCO3&minus;, and SO42&minus; are from the dissolution of dolomite, calcite, gypsum, and other calcium and magnesium bearing minerals. In addition, atmospheric precipitation serves as a replenishment source of natural water in the region, and the recharge is affected by evaporation

Crack Evaluation Based on Novel Circle-Ferrite Induction Thermography

Nondestructive inspection of rolling contact and stress corrosion cracks is a critical important research area in both science and technology industry to evaluate the properties of a product. This paper proposes a novel system of circle-ferrite pulsed inductive thermography for cracks inspection. The new sensing structure consists of several promising characteristics. It significantly enhances the detectability of omnidirectional micro cracks, and provides larger detection area with non-geometry influence. In addition, unlike common inductor, the proposed structure imposes uniform toroidal electromagnetic thermal fields, so that both sensitivities of detection rate and the detectable area can be simultaneously improved. This overcomes the problem of in-homogenous heating, and increases the thermal contrast between directional defective and non-defective region. The theoretical derivation based on magnetic circuit principles has been developed for analysis and interpretation of the results. In addition, both simulation experiments and tests on artificial and nature cracks sample have been conducted to show the reliability and efficiency of the proposed system

Burden of disease resulting from chronic mountain sickness among young Chinese male immigrants in Tibet

Abstract Background In young Chinese men of the highland immigrant population, chronic mountain sickness (CMS) is a major public health problem. The aim of this study was to measure the disease burden of CMS in this population. Methods We used disability-adjusted life years (DALYs) to estimate the disease burden of CMS. Disability weights were derived using the person trade-off methodology. CMS diagnoses, symptom severity, and individual characteristics were obtained from surveys collected in Tibet in 2009 and 2010. The DALYs of individual patients and the DALYs/1,000 were calculated. Results Disability weights were obtained for 21 CMS health stages. The results of the analyses of the two surveys were consistent with each other. At different altitudes, the CMS rates ranged from 2.1-37.4%; the individual DALYs of patients ranged from 0.13-0.33, and the DALYs/1,000 ranged from 3.60-52.78. The age, highland service years, blood pressure, heart rate, smoking rate, and proportion of the sample working in engineering or construction were significantly higher in the CMS group than in the non-CMS group (p p  Conclusion The results show that CMS imposes a considerable burden on Chinese immigrants to Tibet. Immigrants with characteristics such as a higher residential altitude, more advanced age, longer highland service years, being a smoker, and working in engineering or construction were more likely to develop CMS and to increase the disease burden. Higher blood pressure and heart rate as a result of CMS were also positively associated with the disease burden. The authorities should pay attention to the highland disease burden and support the development and application of DALYs studies of CMS and other highland diseases.</p

A Study on the Electro-Optical Properties of Thiol-Ene Polymer Dispersed Cholesteric Liquid Crystal (PDChLC) Films

In this study, a polymer dispersed cholesteric liquid crystal (PDChLC) film obtained via a one-step fabrication technique based on photopolymerization of a thiol-acrylate reaction system was prepared and characterized for the first time. The effects of the chiral dopant, the influence of thiol monomer functionality and content on the morphology and subsequent performance of the PDChLC films were systematically investigated. It was demonstrated that the addition of a small amount of chiral dopant slightly increased the driving voltage, but decreased the off-state transmittance significantly. Furthermore, scanning electron micrographs (SEM) shown that the liquid crystal (LC) droplet size decreased at first and then increased with the increasing amount of thiol monomer functionality, while increasing the thiol content increased the LC droplet size. Correspondingly, the electro-optical switching behavior was directly dependent on LC droplet size. By tuning the raw material composition, PDChLC film with optimized electro-optical performance was prepared