1,702 research outputs found

    Membrane-associated pyruvate kinase in developing guinea-pig liver

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    Evaluation of elicitation methods to quantify Bayes linear models

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    The Bayes linear methodology allows decision makers to express their subjective beliefs and adjust these beliefs as observations are made. It is similar in spirit to probabilistic Bayesian approaches, but differs as it uses expectation as its primitive. While substantial work has been carried out in Bayes linear analysis, both in terms of theory development and application, there is little published material on the elicitation of structured expert judgement to quantify models. This paper investigates different methods that could be used by analysts when creating an elicitation process. The theoretical underpinnings of the elicitation methods developed are explored and an evaluation of their use is presented. This work was motivated by, and is a precursor to, an industrial application of Bayes linear modelling of the reliability of defence systems. An illustrative example demonstrates how the methods can be used in practice

    Local structural studies of Ba1−x_{1-x}Kx_xFe2_2As2_2 using atomic pair distribution function analysis

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    Systematic local structural studies of Ba1−x_{1-x}Kx_xFe2_2As2_2 system are undertaken at room temperature using atomic pair distribution function (PDF) analysis. The local structure of the Ba1−x_{1-x}Kx_xFe2_2As2_2 is found to be well described by the long-range structure extracted from the diffraction experiments, but with anisotropic atomic vibrations of the constituent atoms (U11U_{11} = U22≠U33U_{22} \ne U_{33}). The crystal unit cell parameters, the FeAs4_4 tetrahedral angle and the pnictogen height above the Fe-plane are seen to show systematic evolution with K doping, underlining the importance of the structural changes, in addition to the charge doping, in determining the properties of Ba1−x_{1-x}Kx_xFe2_2As2_2

    OxyCAP UK: Oxyfuel Combustion - academic Programme for the UK

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    The OxyCAP-UK (Oxyfuel Combustion - Academic Programme for the UK) programme was a £2 M collaboration involving researchers from seven UK universities, supported by E.On and the Engineering and Physical Sciences Research Council. The programme, which ran from November 2009 to July 2014, has successfully completed a broad range of activities related to development of oxyfuel power plants. This paper provides an overview of key findings arising from the programme. It covers development of UK research pilot test facilities for oxyfuel applications; 2-D and 3-D flame imaging systems for monitoring, analysis and diagnostics; fuel characterisation of biomass and coal for oxyfuel combustion applications; ash transformation/deposition in oxyfuel combustion systems; materials and corrosion in oxyfuel combustion systems; and development of advanced simulation based on CFD modelling

    Evaluation of CMAF in live streaming scenarios

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    HTTP Adaptive Streaming (HAS) technologies such as MPEG DASH are now used extensively to deliver television services to large numbers of viewers. In HAS, the client requests segments of content using HTTP, with an ABR algorithm selecting the quality at which to request each segment to trade-off video quality with the avoidance of stalling. This introduces significant end to end latency compared to traditional broadcast, due to the the client requiring a large enough buffer for the ABR algorithm to react to changes in network conditions in a timely manner. The recently standardised Common Media Application Format (CMAF) has helped address the issue of latency by defining segments as composed of independently transferable chunks. In this paper, we describe a simulation model we have developed to evaluate the performance of four popular ABR algorithms using DASH and CMAF in various low latency live streaming scenarios. Realistic network conditions are used for the evaluation, which are based on throughput data taken from the CDN logs of a commercial live TV service. We quantify the performance of the ABR algorithms using a selection of QoE metrics, and show that CMAF can significantly improve ABR performance in low delay scenarios

    The molecular characterisation of Cryptosporidium species in relinquished dogs in Great Britain: a novel zoonotic risk?

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    Surveillance was conducted to investigate the occurrence of protozoan parasites of the genus Cryptosporidium in dogs newly admitted to a dog rehoming charity in London, Great Britain. Voided faecal samples were collected from all new admissions between 2011 and 2012 during six separate 4-week sampling periods. Information on host signalment, including age, breed and reason for submission and faecal consistency, was collected. Polymerase Chain Reaction (PCR) targeting the 18S ribosomal RNA gene, confirmed by sequencing, was conducted on the faecal samples to detect Cryptosporidium genomic DNA and determine Cryptosporidium identity. In total, 677 dogs were included in the study. The prevalence of Cryptosporidium-positive faecal samples was 4.6% (31/676). There were positive samples in all of the six sampling periods. Cryptosporidium canis (n = 28), C. parvum (n = 2) and C. andersoni (n = 1) were identified. Sixty KDa glycoprotein (gp60) gene amplicon sequencing of the C. parvum samples identified genotypes IIaA17G1R1 and IIaA15G2R1 for the first time from a dog. There were no significant associations between signalment data and Cryptosporidium status. While this was a study of one rehoming shelter, the presence of the potentially zoonotic C. parvum and C. canis in dogs highlights a public health concern. Further research is needed to better understand the epidemiology and potential impacts of Cryptosporidium infection in dogs

    Llama - Low Latency Adaptive Media Algorithm

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    In the recent years, HTTP Adaptive Bit Rate (ABR) streaming including Dynamic Adaptive Streaming over HTTP (DASH) has become the most popular technology for video streaming over the Internet. The client device requests segments of content using HTTP, with an ABR algorithm selecting the quality at which to request each segment to trade-off video quality with the avoidance of stalling. This introduces high latency compared to traditional broadcast methods, mostly in the client buffer which needs to hold enough data to absorb any changes in network conditions. Clients employ an ABR algorithm which monitors network conditions and adjusts the quality at which segments are requested to maximise the user's Quality of Experience. The size of the client buffer depends on the ABR algorithm's capability to respond to changes in network conditions in a timely manner, hence, low latency live streaming requires an ABR algorithm that can perform well with a small client buffer. In this paper, we present Llama - a new ABR algorithm specifically designed to operate in such scenarios. Our new ABR algorithm employs the novel idea of using two independent throughput measurements made over different timescales. We have evaluated Llama by comparing it against four popular ABR algorithms in terms of multiple QoE metrics, across multiple client settings, and in various network scenarios based on CDN logs of a commercial live TV service. Llama outperforms other ABR algorithms, improving the P.1203 Mean Opinion Score (MOS) as well as reducing rebuffering by 33% when using DASH, and 68% with CMAF in the lowest latency scenario

    Seed systems smallholder farmers use

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    Seed can be an important entry point for promoting productivity, nutrition and resilience among smallholder farmers. While investments have primarily focused on strengthening the formal sector, this article documents the degree to which the informal sector remains the core for seed acquisition, especially in Africa. Conclusions drawn from a uniquely comprehensive data set, 9660 observations across six countries and covering 40 crops, show that farmers access 90.2 % of their seed from informal systems with 50.9 % of that deriving from local markets. Further, 55 % of seed is paid for by cash, indicating that smallholders are already making important investments in this arena. Targeted interventions are proposed for rendering formal and informal seed sector more smallholder-responsive and for scaling up positive impacts

    Spectral line shape of resonant four-wave mixing induced by broad-bandwidth lasers

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    We present a theoretical and experimental study of the line shape of resonant four-wave mixing induced by broad-bandwidth laser radiation that revises the theory of Meacher, Smith, Ewart, and Cooper (MSEC) [Phys. Rev. A 46, 2718 (1992)]. We adopt the same method as MSEC but correct for an invalid integral used to average over the distribution of atomic velocities. The revised theory predicts a Voigt line shape composed of a homogeneous, Lorentzian component, defined by the collisional rate Γ, and an inhomogeneous, Doppler component, which is a squared Gaussian. The width of the inhomogeneous component is reduced by a factor of √2 compared to the simple Doppler width predicted by MSEC. In the limit of dominant Doppler broadening, the width of the homogeneous component is predicted to be 4Γ, whereas in the limit of dominant homogeneous broadening, the predicted width is 2Γ. An experimental measurement is reported of the line shape of the four-wave-mixing signal using a broad-bandwidth, "modeless", laser resonant with the Q1 (6) line of the A2 Σ - X2 Π(0,0) system of the hydroxyl radical. The measured widths of the Voigt components were found to be consistent with the predictions of the revised theory
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