Experimental investigation on a geocontainer Submerged reef

Geotextile sand containers (GSC) have been used as permanent construction elements in coastal works for more than 20 years,becoming more and more popular as an alternative to the most typical coastal structures. Aim of this work is to analyze the hydrodynamic, stability and morphodynamic response of a GSC submerged reef by means of an experimental campaign. The first investigated aspect concerned the hydrodynamics. The reflection and transmission coefficients for regular and random waves were determined: the reflection coefficient decreases with increasing of kh; the transmission coefficient decreases with the increase of the incident wave. As regards the stability of the structure, it was observed that the strongest waves were able to lift the row of GSC more exposed to the wave action. An instability curve for the GSC as a function of the hydrodynamic characteristics was then found. Flow visualization close to the reef was performed by means of ink, showing that the flow becomes asymmetric in the proximity of the structure. Concerning the morphodynamics, long-term tests were performed to calculate the scour. This reached its maximum value at the end of each test and it is present in all three cases. The scour causes serious problems of instability to the structure

Two-scale asymptotic homogenization in a MEMS auxetic structure for over etch identification

The development and optimization of Micro electro-mechanical systems (MEMS) devices, due to their small size scale, require testing and precise characterization. As an example, over etch, which is the deviation between the designed masks and the effective dimensions of the suspended parts, strongly influences the performances of MEMS; therefore, to predict the correct functioning of the device its actual value must be carefully identified. In this work, we propose an efficient, time-saving tool to identify fabrication imperfections in MEMS devices. In particular, we replace the complex geometry of a MEMS mechanical filter with an equivalent homogeneous medium, whose linear-elastic effective properties are evaluated employing two-scale asymptotic homogenization and we identify the over etch by minimizing the relative error between experimental data and corresponding predictions obtained for different combinations of over etch

Caratteristiche sismostratigrafiche di strutture sedimentarie diagnostiche dicorrenti di fondo nell\u2019off-shore del Golfo di Taranto.

L\u2019analisi integrata di dati multibeam e sismici ad altissima risoluzione (Chirp Sub-Bottom), acquisiti in un settore del Golfo di Taranto (Mare Ionio), ha permesso di identificare e classificare strutture sedimentarie diagnostiche di correnti di fondo (conturiti), formatesi nel tardo Quaternario. La classificazione proposta \ue8 basata sia su criteri sismo-stratigrafici che sulla comparazione con strutture analoge documentate da precedenti autori nei bacini oceanici [Faugeres et al., 1999 con rif.]. Nell\u2019area in esame sono stati identificati quattro settori (Alto dell\u2019Amendolara, Bacino di Corigliano, Bacino dell\u2019Amendolara ed Alto di Rossano-Cariati) caratterizzati da morfologia, pendenza e profondit\ue0 differente. Le strutture conturitiche sono state riconosciute prevalentemente nei settori NW e SE dell\u2019alto dell\u2019Amendolara, ad una profondit\ue0 compresa tra 130 m e 400 m e le geometrie interne ed esterne mostrano caratteristiche deposizionali ed erosive. Sono state classificate come sheeted drift le strutture sviluppate subparallelamente al profilo batimetrico, infill drift ed elongated drift le strutture caratterizzate da fosse ben sviluppate ed elementi erosivi quali fosse ed abraded surface. Sono stati osservati inoltre osservati sediment waves nel settore SW dell\u2019alto strutturale. Dall\u2019analisi integrata dei nuovi dati con quelli disponibili in letteratura \ue8 possibile ipotizzare che i fattori che hanno maggiormente influenzato tipologia, distribuzione areale e batimetrica dei depositi conturitici e degli elementi erosivi sono: a) morfologia del fondo marino; b) caratteristiche dei sedimenti (es. tessitura); c) variazione della velocit\ue0 della \u201cLevantine Intermediate Water come conseguenza delle d) variazioni eustatiche. Sono stati inoltre applicati in cascata i modelli bidimensionali CMS- Wave [Lin et al, 2006] per la propagazione dello spettro d\u2019onda, e CMS- Flow [Buttolph et al, 2006] per la circolazione interna, prendendo in considerazione i dati meteo marini forniti dall\u2019ECMWF nel punto di coordinate 39,5\ub0N, 17\ub0E, in modo da valutare le condizioni idrodinamiche in prossimit\ue0 del paraggio in esame. L\u2019integrazione dei dati indicati geologici/geofisici e dei risultati del codice di calcolo numerico ha permesso di ipotizzare un modello di circolazione della corrente \u201cLevantine Intermediate Water\u201d e valutare l\u2019influenza delle morfostrutture sulla circolazione delle acque profonde durante l\u2019ultima fase di abbassamento e stazionamento basso del livello del mare. Bibliografia Buttolph, A.,D., Reed, C.W., Kraus N., Wamsley, T.V., Ono, N., Larson, M.,Camenen, B., Hanson, H. Zundel, A.K., (2006). Two-Dimensional Depth-Averaged Circulation Model CMS-M2D: Version 3.0, Report 2, Sediment Transport and Morphology Change. ERDC/CHL TR-06-9 Vicksburg, MS: U.S. Army Engineer Research and Development Center. Lin, L., H. Mase, F. Yamada, and Z. Demirbilek. (2006). Wave-action balance equation diffraction (WABED) model: Tests of wave diffraction and reflection at inlets. Coastal and Hydraulics Engineering Technical Note ERDC/CHL CHETN-III-73. Vicksburg, MS: U.S. Army Engineer Research and Development Center. Faug\ue8res, J.C., Stow, D.A.V., Imbert, P., Viana, A.R. (1999). Seismic feature diagnostic of contourite drifts. Marine Geology 162, pp. 1-38

Performance of the galactomannan antigen detection test in the diagnosis of invasive aspergillosis in children with cancer or undergoing haemopoietic stem cell transplantation

AbstractSerum galactomannan (GM) antigen detection is not recommended for defining invasive aspergillosis (IA) in children undergoing aggressive chemotherapy or allogeneic haemopoietic stem cell transplantation (HSCT). The ability of the GM test to identify IA in children was retrospectively evaluated in a cohort of children. Test performance was evaluated on samples that were collected during 195 periods at risk of IA. Proven IA was diagnosed in seven periods, all with positive GM test results (true positives, 4%), and possible IA was diagnosed in 15 periods, all with negative GM test results (false negatives, 8%). The test result was positive with negative microbiological, histological and clinical features in three periods (false positives, 1%), and in 170 periods it was negative with negative microbiological, histological and clinical features (true negatives, 87%). The sensitivity was 0.32 and the specificity was 0.98; the positive predictive value was 0.70 and the negative predictive value was 0.92. The efficiency of the test was 0.91, the positive likelihood ratio was 18.3, and the negative likelihood ratio was 1.4. The probability of missing an IA because of a negative test result was 0.03. Test performance proved to be better during at-risk periods following chemotherapy than in periods following allogeneic HSCT. The GM assay is useful for identifying periods of IA in children undergoing aggressive chemotherapy or allogeneic HSCT

Nadroparine-induced skin necrosis on a patient with essential thrombocythaemia: a case report

Skin necrosis is a rare but serious complication of subcutaneously administered low-molecular-weight heparin. We report a case of a 53-year-old female patient with skin necrosis induced by subcutaneous administration of nadroparine. The patient suffered from essential thrombocythaemia on a background of chronic myeloproliferative disease. She was admitted to our clinic with a subacute ileus due to endometriosis of the rectosigmoid junction. She underwent a high anterior resection and she received pre- and postoperative antithrombotic prophylaxis with subcutaneous nadroparine on a daily basis. On the 6th and 7th postoperative days, two skin necroses occurred at two injection sites