La concessione in uso dei beni culturali nel Codice dei beni culturali e del paesaggio

1noThe regulation on the Cultural Heritage individual use. The Italian Code of Cultural and Environmental Heritage, at art. 106, illustrates the concept of the socalled "individual use" of objects included in the Cultural Heritage that are belonging to public Authorities. The Code, in regulating the matter, aims at furnishing a definition of the specific scope of the law enforcement - in both the subjective and objective points of view -but the rule does not clearly outline neither the content of the relation between Administrations and dealers nor the nature of the rights established in favour of the latter ones. Consequently, this analysis is centred on clarifying the exact content of the subjective position arising from the rule.openA. FANTINFantin, Andre

La tutela del Codice Atlantico di Leonardo tra lo Stato e la Regione Lombardia

The responsibility for the conservation of Leonardo's Atlantic Codex, between State and Lombardy Region. Starting point of this paper is the debate, which arose between the Ministry of Cultural Heritage and the Lombardy Region, and concerning who is the real holder of the responsibility for the preservation of the Leonardo Da Vinci's Atlantic Codex, today property of the mbrosiana Library in Milan. The dispute derives from the genesis of the Codex (initially single leaves, only later bound together by a person different by the author) and the heterogeneity of the documents collected in it, something which does not allow to absolutely affirm that the Codex is a book, or a collection of separate drawings or manuscripts. As highlighted by the paper in fact, the different choice to consider the Codex a book (as a whole), or otherwise a collection of single drawings or manuscripts (i.e. made of single entities), results in shifting - according to the rules in force - the holder of the responsibility to one or to the other authority

Colelitíase.

Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis, 197

Estratigrafía y análisis de facies de la Formación Vaca Muerta en el área de El Trapial

La importancia de los análisis estratigráficos, de facies y sedimentológicos para evaluar el potencial de un reservorio no convencional para identificar las zonas más favorables para la prospección y explotación de hidrocarburos.Fil: González Tomassini, Federico. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Geología; ArgentinaFil: Kietzmann, Diego Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Estudios Andinos "Don Pablo Groeber". Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Estudios Andinos ; ArgentinaFil: Fantin, Manuel A.. Chevron; ArgentinaFil: Crousse, Luisa C.. Chevron; ArgentinaFil: Reijenstein, Hernán M.. Chevron Latin America Business; Estados Unido

Geotecnologias e aprendizagem espacial em ambiente educacional: o mapeamento de nascentes utilizando técnicas de geoprocessamento por meio de softwares livres.

The headwaters of streams are extremely important to maintain the water sources and contribute to the permanent preservation areas (PPA) and hence with the ecosystems of any region. Thus this aspect were investigated by mapping using GIS techniques by free software. The data were validated by field research conducted by students of the 1st year of high school ? Escola Estadual de Ensino Médio Pedro Migliorini, located in the municipality of Monte Belo do Sul, Brazil. The objective of the study was to allow students to assess quantitatively and qualitatively the headwaters of the city, analyzing water usage, as well as the situation of the same as the environmental laws. Students were divided into work areas, conducted interviews with landowners in order to research on the consumption and use of water and what methods are used for the preservation of the spring on the property. To assess if the sources informed the owners comply with current legislation, GIS tools were employed and was generated a buffer of 50 meters (area corresponding to PPA) around the source. At the end of the study were located 427 points with the following observations: 1) 95 are used for human consumption, 2) 107 for animal consumption, 3) 145 have some protection; 4) 23 are in accordance with current legislation . 37 springs were not informed about the use

Dark Matter Direct Detection with Non-Maxwellian Velocity Structure

The velocity distribution function of dark matter particles is expected to show significant departures from a Maxwell-Boltzmann distribution. This can have profound effects on the predicted dark matter - nucleon scattering rates in direct detection experiments, especially for dark matter models in which the scattering is sensitive to the high velocity tail of the distribution, such as inelastic dark matter (iDM) or light (few GeV) dark matter (LDM), and for experiments that require high energy recoil events, such as many directionally sensitive experiments. Here we determine the velocity distribution functions from two of the highest resolution numerical simulations of Galactic dark matter structure (Via Lactea II and GHALO), and study the effects for these scenarios. For directional detection, we find that the observed departures from Maxwell-Boltzmann increase the contrast of the signal and change the typical direction of incoming DM particles. For iDM, the expected signals at direct detection experiments are changed dramatically: the annual modulation can be enhanced by more than a factor two, and the relative rates of DAMA compared to CDMS can change by an order of magnitude, while those compared to CRESST can change by a factor of two. The spectrum of the signal can also change dramatically, with many features arising due to substructure. For LDM the spectral effects are smaller, but changes do arise that improve the compatibility with existing experiments. We find that the phase of the modulation can depend upon energy, which would help discriminate against background should it be found.Comment: 34 pages, 16 figures, submitted to JCAP. Tables of g(v_min), the integral of f(v)/v from v_min to infinity, derived from our simulations, are available for download at http://astro.berkeley.edu/~mqk/dmdd

Relation between composition and vacant oxygen sites in the mixed ionicelectronic conductors La5.4W1 yMyO12 delta M Mo, Re; 0 lt; y lt; 0.2 and their mother compound La6 xWO12 delta 0.4 lt; x lt; 0.8

A detailed analysis of specimen composition, water uptake and their interrelationship in the systems La6 xWO12 amp; 948; 0.4 amp; 8804; x amp; 8804;0.8 and La6 xW1 yMyO12 amp; 948; 0 amp; 8804;y amp; 8804;0.2; M Mo, Re is presented. The three specimen series were investigated in dry and wet D2O conditions. A systematic trend in mass loss and onset temperature variation was observed in La6 xWO12 amp; 948; 0.4 amp; 8804;x amp; 8804;0.8 . Even very small amounts lt; 1 wt of secondary phases were found to notably modify the specimen s water uptake and onset temperature of mass loss. The theoretical model for vacancy concentration available was used to calculate the vacant oxygen sites starting from mass loss values determined by thermogravimetry. A discrepancy between the calculated and observed concentration of vacant oxygen sites is observed for all three systems. The effect of substitution of W by Re or Mo on the vacancy amount is explained taking into account diffraction measurements and information on the oxidation state of the substituting elements Mo and R

Neuropilin 1 regulation of vascular permeability signaling

The vascular endothelium acts as a selective barrier to regulate macromolecule exchange between the blood and tissues. However, the integrity of the endothelium barrier is compromised in an array of pathological settings, including ischemic disease and cancer, which are the leading causes of death worldwide. The resulting vascular hyperpermeability to plasma molecules as well as leukocytes then leads to tissue damaging edema formation and inflammation. The vascular endothelial growth factor A (VEGFA) is a potent permeability factor, and therefore a desirable target for impeding vascular hyperpermeability. However, VEGFA also promotes angiogenesis, the growth of new blood vessels, which is required for reperfusion of ischemic tissues. Moreover, edema increases interstitial pressure in poorly perfused tumors, thereby affecting the delivery of therapeutics, which could be counteracted by stimulating the growth of new functional blood vessels. Thus, targets must be identified to accurately modulate the barrier function of blood vessels without affecting angiogenesis, as well as to develop more effective pro‐ or anti‐angiogenic therapies. Recent studies have shown that the VEGFA co‐receptor neuropilin 1 (NRP1) could be playing a fundamental role in steering VEGFA‐induced responses of vascular endothelial cells towards angiogenesis or vascular permeability. Moreover, NRP1 is involved in mediating permeability signals induced by ligands other than VEGFA. This review therefore focuses on current knowledge on the role of NRP1 in the regulation of vascular permeability signaling in the endothelium to provide an up‐to‐date landscape of the current knowledge in this field

Neuropilin 1 Regulation of Vascular Permeability Signaling.

The vascular endothelium acts as a selective barrier to regulate macromolecule exchange between the blood and tissues. However, the integrity of the endothelium barrier is compromised in an array of pathological settings, including ischemic disease and cancer, which are the leading causes of death worldwide. The resulting vascular hyperpermeability to plasma molecules as well as leukocytes then leads to tissue damaging edema formation and inflammation. The vascular endothelial growth factor A (VEGFA) is a potent permeability factor, and therefore a desirable target for impeding vascular hyperpermeability. However, VEGFA also promotes angiogenesis, the growth of new blood vessels, which is required for reperfusion of ischemic tissues. Moreover, edema increases interstitial pressure in poorly perfused tumors, thereby affecting the delivery of therapeutics, which could be counteracted by stimulating the growth of new functional blood vessels. Thus, targets must be identified to accurately modulate the barrier function of blood vessels without affecting angiogenesis, as well as to develop more effective pro- or anti-angiogenic therapies. Recent studies have shown that the VEGFA co-receptor neuropilin 1 (NRP1) could be playing a fundamental role in steering VEGFA-induced responses of vascular endothelial cells towards angiogenesis or vascular permeability. Moreover, NRP1 is involved in mediating permeability signals induced by ligands other than VEGFA. This review therefore focuses on current knowledge on the role of NRP1 in the regulation of vascular permeability signaling in the endothelium to provide an up-to-date landscape of the current knowledge in this field