Diffusion in a crowded environment

We analyze a pair of diffusion equations which are derived in the infinite system--size limit from a microscopic, individual--based, stochastic model. Deviations from the conventional Fickian picture are found which ultimately relate to the depletion of resources on which the particles rely. The macroscopic equations are studied both analytically and numerically, and are shown to yield anomalous diffusion which does not follow a power law with time, as is frequently assumed when fitting data for such phenomena. These anomalies are here understood within a consistent dynamical picture which applies to a wide range of physical and biological systems, underlining the need for clearly defined mechanisms which are systematically analyzed to give definite predictions.Comment: 4 pages, 3 figures, minor change

Experimental perspectives for systems based on long-range interactions

The possibility of observing phenomena peculiar to long-range interactions, and more specifically in the so-called Quasi-Stationary State (QSS) regime is investigated within the framework of two devices, namely the Free-Electron Laser (FEL) and the Collective Atomic Recoil Laser (CARL). The QSS dynamics has been mostly studied using the Hamiltonian Mean-Field (HMF) toy model, demonstrating in particular the presence of first versus second order phase transitions from magnetized to unmagnetized regimes in the case of HMF. Here, we give evidence of the strong connections between the HMF model and the dynamics of the two mentioned devices, and we discuss the perspectives to observe some specific QSS features experimentally. In particular, a dynamical analog of the phase transition is present in the FEL and in the CARL in its conservative regime. Regarding the dissipative CARL, a formal link is established with the HMF model. For both FEL and CARL, calculations are performed with reference to existing experimental devices, namely the FERMI@Elettra FEL under construction at Sincrotrone Trieste (Italy) and the CARL system at LENS in Florence (Italy)

Far-Ultraviolet Color Gradients in Early-Type Galaxies

We discuss far-UV (1500 A) surface photometry and FUV-B color profiles for 8 E/S0 galaxies from images taken with the Ultraviolet Imaging Telescope, primarily during the Astro-2 mission. In three cases, the FUV radial profiles are more consistent with an exponential than a de Vaucouleurs function, but there is no other evidence for the presence of a disk or of young, massive stars. In all cases except M32 the FUV-B color becomes redder at larger radii. There is a wide range of internal radial FUV-B color gradients. However, we find no correlation between the FUV-B color gradients and internal metallicity gradients based on Mg absorption features. We conclude that metallicity is not the sole parameter controlling the "UV upturn component" in old populations.Comment: 11 pages; tar.gz file includes LaTeX text file, 3 PostScript figures. Paper to be published in ApJ Letter

An unusual dysphagia for solids in a 17-year-old girl due to a lusoria artery: A case report and review of the literature

Background: Dysphagia is a condition that can have many underlying causes, often different between adults and children and its early diagnosis is crucial especially during childhood and adolescence, given the importance of proper nutritional intake to ensure adequate growth and development. Case report: We described the case of a 17-year-old girl reporting dysphagia for solids for approximately one month. No symptoms were previously referred. Oesophagogastroduodenoscopy was performed, detecting an image of ab extrinseco compression at the level of the mid-cervical oesophagus. An upper gastrointestinal tract radiography confirmed an oesophageal impression above the arch of the aorta suggestive of vascular abnormality. Computed tomography angiography and three-dimensional reconstruction techniques showed the presence of a lusoria artery that originated from the medial margin of the descending aorta and crossed the trachea and oesophagus posteriorly to the distal third. The lusoria artery was transected via a left thoracotomy and re-implanted into the right common carotid artery with complete symptom resolution. Conclusions: Dysphagia lusoria is an impairment of swallowing due to compression from an aberrant right subclavian artery. The diagnosis is always difficult, as the symptoms are often nonspecific. It is imperative to accurately identify and properly manage dysphagia in pediatric age and this is only possible with an anamnestic, clinical and instrumental process that takes into account an adequate differential diagnosis

Kondo behavior, ferromagnetic correlations, and crystal fields in the heavy Fermion compounds Ce3X (X=In, Sn)

We report measurements of inelastic neutron scattering, magnetic susceptibility, magnetization, and the magnetic field dependence of the specific heat for the heavy Fermion compounds Ce$_3$In and Ce$_3$Sn. The neutron scattering results show that the excited crystal field levels have energies $E_1$ = 13.2 meV, $E_2$ = 44.8 meV for Ce$_3$In and $E_1$ = 18.5 meV, $E_2$ = 36.1 meV for Ce$_3$Sn. The Kondo temperature deduced from the quasielastic linewidth is 17 K for Ce$_3$In and 40 K for Ce$_3$Sn. The low temperature behavior of the specific heat, magnetization, and susceptibility can not be well-described by J=1/2 Kondo physics alone, but require calculations that include contributions from the Kondo effect, broadened crystal fields, and ferromagnetic correlations, all of which are known to be important in these compounds. We find that in Ce$_3$In the ferromagnetic fluctuation makes a 10-15 % contribution to the ground state doublet entropy and magnetization. The large specific heat coefficient $\gamma$ in this heavy fermion system thus arises more from the ferromagnetic correlations than from the Kondo behavior.Comment: 8 pages, 6 figure

Analytical study of non Gaussian fluctuations in a stochastic scheme of autocatalytic reactions

A stochastic model of autocatalytic chemical reactions is studied both numerically and analytically. The van Kampen perturbative scheme is implemented, beyond the second order approximation, so to capture the non Gaussianity traits as displayed by the simulations. The method is targeted to the characterization of the third moments of the distribution of fluctuations, originating from a system of four populations in mutual interaction. The theory predictions agree well with the simulations, pointing to the validity of the van Kampen expansion beyond the conventional Gaussian solution.Comment: 15 pages, 8 figures, submitted to Phys. Rev.

Nonexistence of extremals for the adjoint restriction inequality on the hyperboloid

We study the problem of existence of extremizers for the $L^2$ to $L^p$ adjoint Fourier restriction inequalities on the hyperboloid in dimensions 3 and 4, in which cases $p$ is an even integer. We will use the method developed by Foschi to show that extremizers do not exist.Comment: 32 pages. Correction for Theorem 1.2 and Proposition 7.5 and addition of Remark 1.

Enniatin and Beauvericin Biosynthesis in Fusarium Species: Production Profiles and Structural Determinant Prediction

Citation: Liuzzi, V. C., Mirabelli, V., Cimmarusti, M. T., Haidukowski, M., Leslie, J. F., Logrieco, A. F., . . . Mule, G. (2017). Enniatin and Beauvericin Biosynthesis in Fusarium Species: Production Profiles and Structural Determinant Prediction. Toxins, 9(2), 17. doi:10.3390/toxins9020045Members of the fungal genus Fusarium can produce numerous secondary metabolites, including the nonribosomal mycotoxins beauvericin (BEA) and enniatins (ENNs). Both mycotoxins are synthesized by the multifunctional enzyme enniatin synthetase (ESYN1) that contains both peptide synthetase and S-adenosyl-L-methionine-dependent N-methyltransferase activities. Several Fusarium species can produce ENNs, BEA or both, but the mechanism(s) enabling these differential metabolic profiles is unknown. In this study, we analyzed the primary structure of ESYN1 by sequencing esyn1 transcripts from different Fusarium species. We measured ENNs and BEA production by ultra-performance liquid chromatography coupled with photodiode array and Acquity QDa mass detector (UPLC-PDA-QDa) analyses. We predicted protein structures, compared the predictions by multivariate analysis methods and found a striking correlation between BEA/ENN-producing profiles and ESYN1 three-dimensional structures. Structural differences in the beta strand's Asn789-Ala793 and His797-Asp802 portions of the amino acid adenylation domain can be used to distinguish BEA/ENN-producing Fusarium isolates from those that produce only ENN

Comparison between finite element and experimental evidences of innovative W lattice materials for sacrificial limiter applications

Power exhaust is a key mission for the realization of fusion electricity. Engineering challenges may arise from the extreme heat fluxes developed during plasma transients, above the limit offered by existing materials. These can reduce the lifetime of plasma-facing components (PFCs), imposing extraordinary maintenance, reactor safety issues and ultimately delayed return to normal operation. Concerning the EU DEMO reactor, discrete sacrificial limiters are being investigated as the last safety resource of the reactor's wall in case of unmitigated events. Within this context, micro-engineered tungsten (W) lattices are proposed to cope with unmitigated plasma disruptions. Unlike bulk W, lattices can be tailored to meet the operational requirements of the limiter, compromise between steady-state and off-design performances while avoiding overloading of the heat sink and delay the need for extraordinary maintenance. By calibrating an equivalent solid model originally developed and validated for open-cell aluminum (Al) foams, tailored lattices have been modelled and samples fabricated through additive manufacturing for characterization and testing, currently ongoing. In the present work, the thermal response of lattice samples during thermal shock high heat flux (HHF) tests performed at the linear facility QSPA Kh-50 facility is simulated using ANSYS and compared with available results. Enthalpy changes of W were imposed to simulate phase change. Good agreement with experiments and SDC-IC reference up to melting point was observed. Ultimately, a thermal quench of an unmitigated DEMO disruption was simulated involving an original MAPDL routine that removes mesh elements at the melting or vaporization point.s