838 research outputs found

    Improving feature selection algorithms using normalised feature histograms

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    The proposed feature selection method builds a histogram of the most stable features from random subsets of a training set and ranks the features based on a classifier based cross-validation. This approach reduces the instability of features obtained by conventional feature selection methods that occur with variation in training data and selection criteria. Classification results on four microarray and three image datasets using three major feature selection criteria and a naive Bayes classifier show considerable improvement over benchmark results

    BOLD signal physiology: Models and applications

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    The BOLD contrast mechanism has a complex relationship with functional brain activity, oxygen metabolism, and neurovascular factors. Accurate interpretation of the BOLD signal for neuroscience and clinical applications necessitates a clear understanding of the sources of BOLD contrast and its relationship to underlying physiology. This review describes the physiological components that contribute to the BOLD signal and the steady-state calibrated BOLD models that enable quantification of functional changes with a separate challenge paradigm. The principles derived from these biophysical models are then used to interpret BOLD measurements in different neurological disorders in the presence of confounding vascular factors related to disease

    LEAN BEHAVIOR IMPACT TOWARDS LEAN MANAGEMENT: A CASE STUDY

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    Lean behavior is an essential element to create a continuous improvement culture in the service organization. Meanwhile, continuous improvement is defined as the never-ending efforts for improvement involving everyone in organization. The purpose of this study is to evaluate the changes of behavior practices after the introduction of lean tools and to discuss on how lean behavior in developing the continuous improvement culture in an office environment. This study focuses on self-administered questionnaire method to obtain the real time data for the analysis of behavior practices. Ford Questionnaire is used and distributed to the employees of different management levels in Business Development and IT department. The obtained results are analyzed using the Statistical Package for the Social Sciences (SPSS) software. The same questionnaire survey is conducted after the introduction of lean tools. The expected outcomes of this study is to determine the level of lean behavior practices in the office department and to provide a clear understanding on some lean behavior practices that need to be nurtured among the employees in order to produce a healthy work environment

    Active Galactic Nuclei at the Crossroads of Astrophysics

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    Over the last five decades, AGN studies have produced a number of spectacular examples of synergies and multifaceted approaches in astrophysics. The field of AGN research now spans the entire spectral range and covers more than twelve orders of magnitude in the spatial and temporal domains. The next generation of astrophysical facilities will open up new possibilities for AGN studies, especially in the areas of high-resolution and high-fidelity imaging and spectroscopy of nuclear regions in the X-ray, optical, and radio bands. These studies will address in detail a number of critical issues in AGN research such as processes in the immediate vicinity of supermassive black holes, physical conditions of broad-line and narrow-line regions, formation and evolution of accretion disks and relativistic outflows, and the connection between nuclear activity and galaxy evolution.Comment: 16 pages, 5 figures; review contribution; "Exploring the Cosmic Frontier: Astrophysical Instruments for the 21st Century", ESO Astrophysical Symposia Serie

    Magnetization Plateaux in Bethe Ansatz Solvable Spin-S Ladders

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    We examine the properties of the Bethe Ansatz solvable two- and three-leg spin-SS ladders. These models include Heisenberg rung interactions of arbitrary strength and thus capture the physics of the spin-SS Heisenberg ladders for strong rung coupling. The discrete values derived for the magnetization plateaux are seen to fit with the general prediction based on the Lieb-Schultz- Mattis theorem. We examine the magnetic phase diagram of the spin-1 ladder in detail and find an extended magnetization plateau at the fractional value =1/2 = {1/2} in agreement with the experimental observation for the spin-1 ladder compound BIP-TENO.Comment: 11 pages, 1 figur

    Geometric effects on T-breaking in p+ip and d+id superconductors

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    Superconducting order parameters that change phase around the Fermi surface modify Josephson tunneling behavior, as in the phase-sensitive measurements that confirmed dd order in the cuprates. This paper studies Josephson coupling when the individual grains break time-reversal symmetry; the specific cases considered are p±ipp \pm ip and d±idd \pm id, which may appear in Sr2_2RuO4_4 and Nax_xCoO2⋅_2 \cdot (H2_2O)y_y respectively. TT-breaking order parameters lead to frustrating phases when not all grains have the same sign of time-reversal symmetry breaking, and the effects of these frustrating phases depend sensitively on geometry for 2D arrays of coupled grains. These systems can show perfect superconducting order with or without macroscopic TT-breaking. The honeycomb lattice of superconducting grains has a superconducting phase with no spontaneous breaking of TT but instead power-law correlations. The superconducting transition in this case is driven by binding of fractional vortices, and the zero-temperature criticality realizes a generalization of Baxter's three-color model.Comment: 8 page

    Composition and structure of the RuO2(110) surface in an O2 and CO environment: implications for the catalytic formation of CO2

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    The phase diagram of surface structures for the model catalyst RuO2(110) in contact with a gas environment of O2 and CO is calculated by density-functional theory and atomistic thermodynamics. Adsorption of the reactants is found to depend crucially on temperature and partial pressures in the gas phase. Assuming that a catalyst surface under steady-state operation conditions is close to a constrained thermodynamic equilibrium, we are able to rationalize a number of experimental findings on the CO oxidation over RuO2(110). We also calculated reaction pathways and energy barriers. Based on the various results the importance of phase coexistence conditions is emphasized as these will lead to an enhanced dynamics at the catalyst surface. Such conditions may actuate an additional, kinetically controlled reaction mechanism on RuO2(110).Comment: 12 pages including 8 figure files. Submitted to Phys. Rev. B. Related publications can be found at http://www.fhi-berlin.mpg.de/th/paper.htm

    Modeling of the transient interstitial diffusion of implanted atoms during low-temperature annealing of silicon substrates

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    It has been shown that many of the phenomena related to the formation of "tails" in the low-concentration region of ion-implanted impurity distribution are due to the anomalous diffusion of nonequilibrium impurity interstitials. These phenomena include boron implantation in preamorphized silicon, a "hot" implantation of indium ions, annealing of ion-implanted layers et cetera. In particular, to verify this microscopic mechanism, a simulation of boron redistribution during low-temperature annealing of ion-implanted layers has been carried out under different conditions of transient enhanced diffusion suppression. Due to the good agreement with the experimental data, the values of the average migration length of nonequilibrium impurity interstitials have been obtained. It has been shown that for boron implanted into a silicon layer preamorphized by germanium ions the average migration length of impurity interstitials at the annealing temperature of 800 Celsius degrees be reduced from 11 nm to approximately 6 nm due to additional implantation of nitrogen. The further shortening of the average migration length is observed if the processing temperature is reduced to 750 Celsius degrees. It is also found that for implantation of BF2 ions into silicon crystal, the value of the average migration length of boron interstitials is equal to 7.2 nm for thermal treatment at a temperature of 800 Celsius degrees.Comment: 10 pages, 6 figures, RevTe

    Improved Parkinson’s disease classification from diffusion MRI data by Fisher vector descriptors

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    Due to the complex clinical picture of Parkinson’s disease (PD), the reliable diagnosis of patients is still challenging. A promising approach is the structural characterization of brain areas affected in PD by diffusion magnetic resonance imaging (dMRI). Standard classification methods depend on an accurate non-linear alignment of all images to a common reference template, and are challenged by the resulting huge dimensionality of the extracted feature space. Here, we propose a novel diagnosis pipeline based on the Fisher vector algorithm. This technique allows for a precise encoding into a high-level descriptor of standard diffusion measures like the fractional anisotropy and the mean diffusivity, extracted from the regions of interest (ROIs) typically involved in PD. The obtained low dimensional, fixed-length descriptors are independent of the image alignment and boost the linear separability of the problem in the description space, leading to more efficient and accurate diagnosis. In a test cohort of 50 PD patients and 50 controls, the implemented methodology outperforms previous methods when using a logistic linear regressor for classification of each ROI independently, which are subsequently combined into a single classification decision
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