11 research outputs found

    Soy Niña

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    Este libro pretende contribuir al reencuentro de la educación con esas finalidades que verdaderamente importan a una niña o un niño: ser feliz, jugar, vivir juntos y (no) aprender. Para ello hemos puesto el arte, nuestras experiencias y el saber acumulado al servicio del disfrute, el cuestionamiento, el análisis crítico y la construcción común de un presente deseable. Un texto colaborativo coordinado por Ignacio Calderón Almendros y realizado por alumnado de Educación y Cambio Social en el Grado en Educación Infantil de la Universidad de Málaga

    Gestión del conocimiento en equipos de trabajo: factores favorecedores

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    Chilling injury in local and modern peach cultivars from a Spanish peach bank germplasm

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    8 Pags.- 5 Figs.- 4 Tabls.Peaches and nectarines are climacteric fruits with a relatively short storage potential due to rapid ripening and deterioration. Cold storage is effective in extending shelf-life, and preserving fruit quality properties; however, it can lead to the development of a disorder known as chilling injury (CI), perceived when fruit reaches consumer. In the present work, 51 local Spanish and 57 non-Spanish cultivars from the peach germplasm collection established at the Experimental Station of Aula Dei (Zaragoza, Spain) were evaluated after storage of fruit at 5°C (CI inducing conditions) for 2 and 4 weeks. Given the large influence of pre-harvest factors on post-harvest performance of peaches, harvest and postharvest phenotype information was obtained. Basic fruit quality parameters as soluble solids content (SSC), firmness (N), titratable acidity (TA), and ripening index (SSC/TA) were determined. Biochemical compounds such as total phenolics content (TPC) and anthocyanins content (AC) were also obtained. In addition, the enzymatic activity of phenylalanine ammonia-lyase (PAL) was determined to study its correlation with CI symptoms. Statistical analyses emphasized differences between the assayed cultivars and highlighted their origin as a key factor affecting metabolite profiles and susceptibility to chilling injury during cold storage.This current study was funded by grant RTI-2018-094176-R-C33 funded by MCIN/AEI/10.13039/501100011033 and “ERDF A way of making EUROPE”, and the Regional Government of Aragon (A44, T07_17R, A22_20R).Peer reviewe

    Roux-en-Y Gastric Bypass Modulates AMPK, Autophagy and Inflammatory Response in Leukocytes of Obese Patients

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    Obesity is characterized by low-grade chronic inflammation, metabolic overload, and impaired endothelial and cardiovascular function. Roux-en-Y gastric bypass (RYGB) results in amelioration of the pro-oxidant status of leukocytes and the metabolic profile. Nevertheless, little is known about the precise mechanism that drives systemic and metabolic improvements following bariatric surgery. In this cohort study, we investigated the effect of RYGB on molecular pathways involving energy homeostasis in leukocytes in 43 obese subjects one year after surgery. In addition to clinical and biochemical parameters, we determined protein expression of systemic proinflammatory cytokines by Luminex®, different markers of inflammation, endoplasmic reticulum (ER) stress, autophagy/mitophagy by western blot, and mitochondrial membrane potential by fluorescence imaging. Bariatric surgery induced an improvement in metabolic outcomes that was accompanied by a systemic drop in hsCRP, IL6, and IL1β levels, and a slowing down of intracellular inflammatory pathways in leukocytes (NF-κB and MCP-1), an increase in AMPK content, a reduction of ER stress (ATF6 and CHOP), augmented autophagy/mitophagy markers (Beclin 1, ATG5, LC3-I, LC3-II, NBR1, and PINK1), and a decrease of mitochondrial membrane potential. These findings shed light on the specific molecular mechanisms by which RYGB facilitates metabolic improvements, highlighting the relevance of pathways involving energy homeostasis as key mediators of these outcomes. In addition, since leukocytes are particularly exposed to physiological changes, they could be used in routine clinical practice as a good sensor of the whole body’s responses

    Habitabilidad y política de vivienda

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    En esta obra, en la que participan destacados investigadores y profesores, dedicados al estudio de la problemática habitacional se presentan diferentes análisis que permiten conocer cuales son las condiciones de habitabilidad y las características de la actual política de vivienda de México. En sus capítulos se abordan los principales desafíos que enfrentan las familias mexicanas para acceder a una vivienda digna y decorosa y cuales son los retos económicos, políticos, territoriales, arquitectónicos, ambientales, financieros y culturales de las formas de producción habitacional en México y en otros países, en el marco de una sociedad global

    An Overview of Research on Gender in Spanish Society

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