A Text-linguistic Approach To Teaching Translation And The Impact On Iranian Students

Kajian ini melihat bagaimana kursus teks-linguistik mempengaruhi pelajar-pelajar Universiti di Iran. The present study investigates the influence of a text-linguistic course on some Iranian University students

Effect of marketing knowledge management on organizational performance: A Case study in Iran insurance of Kermanshah

The aim of this paper is to study the effect of marketing knowledge management on organizational performance of Iranshahr Insurance of Kermanshah. For this purpose, 82 employees of this company were selected with the use of simple random sampling method and responded to self-made questionnaire of the research. The obtained data from these questionnaires were analyzed by using two-variable regression test. The results indicated that assets and capabilities of marketing knowledge management have significant effect (p<0.01) on general performance, market-related performance, customers’ performance and financial performance of Iranshahr Insurance company of Kermanshah

Effect of marketing knowledge management on organizational performance: A Case study in Iran insurance of Kermanshah

The aim of this paper is to study the effect of marketing knowledge management on organizational performance of Iranshahr Insurance of Kermanshah. For this purpose, 82 employees of this company were selected with the use of simple random sampling method and responded to self-made questionnaire of the research. The obtained data from these questionnaires were analyzed by using two-variable regression test. The results indicated that assets and capabilities of marketing knowledge management have significant effect (p<0.01) on general performance, market-related performance, customers’ performance and financial performance of Iranshahr Insurance company of Kermanshah

Fungi associated oral cavity hygiene and denture stomatitis: A review on diagnostic and treatment

Oral mucosal diseases, communications of opportunistic fungi with oral bacteria, host defense, and predisposing factors can affect oral hygiene. Denture stomatitis is a common inflammatory reaction with multifactorial etiology that is affected by oral hygiene. One of the most important factors that affect this condition is fungi, particularly Candida albicans. Accurate identification of etiologic agents of stomatitis at the species level is essential for selecting an effective drug and definitive treatment. The purpose of this article is to investigate the factors that are affected by oral hygiene with priority on the effect of Candida spp. on denture wearers

Identifying and prioritizing capabilities and skills necessary for marketing knowledge-based companies of Science and Technology Park in Kermanshah

The aim of this study is identifying and prioritizing capabilities and skills necessary for marketing knowledge-based companies of Science and Technology Park in Kermanshah. For this purpose 120 of experts, deputies and managers of knowledge-basedcompanies of Science and Technology Park in Kermanshah have been selected with the use of simple random sampling method and responded to the author-made questionnaire and finally, the obtained data from the research sample have been analyzed with the use of single-sample t-test. The results indicate that from the point of view of the experts, deputies and managers of knowledge-based companies of Science and Technology Park in Kermanshah inclination toward learning, team work skills, communicational skills, analytical skills, planning skills and sales management skills are considered as necessary skills for marketing knowledge-based companies of Science and Technology Park in Kermanshah (p<0.01) and also strategic marketing, international marketing and exports, research and analysis of market, innovation and development of new products, service and internet marketing are among necessary capabilities for marketing knowledge-based companies of Science and Technology Park in Kermanshah (p<0.01)

Identifying and prioritizing capabilities and skills necessary for marketing knowledge-based companies of Science and Technology Park in Kermanshah

The aim of this study is identifying and prioritizing capabilities and skills necessary for marketing knowledge-based companies of Science and Technology Park in Kermanshah. For this purpose 120 of experts, deputies and managers of knowledge-basedcompanies of Science and Technology Park in Kermanshah have been selected with the use of simple random sampling method and responded to the author-made questionnaire and finally, the obtained data from the research sample have been analyzed with the use of single-sample t-test. The results indicate that from the point of view of the experts, deputies and managers of knowledge-based companies of Science and Technology Park in Kermanshah inclination toward learning, team work skills, communicational skills, analytical skills, planning skills and sales management skills are considered as necessary skills for marketing knowledge-based companies of Science and Technology Park in Kermanshah (p<0.01) and also strategic marketing, international marketing and exports, research and analysis of market, innovation and development of new products, service and internet marketing are among necessary capabilities for marketing knowledge-based companies of Science and Technology Park in Kermanshah (p<0.01)

A health concern regarding the protein corona, aggregation and disaggregation

Nanoparticle (NP)-protein complexes exhibit the correct identity of NP in biological media. Therefore, protein-NP interactions should be closely explored to understand and to modulate the nature of NPs in medical implementations. This review focuses mainly on the physicochemical parameters such as dimension, surface chemistry, the morphology of NPs and influence of medium pH on the formation of protein corona and conformational changes of adsorbed proteins by different kinds of methods. Also, the impact of protein corona on the colloidal stability of NPs is discussed. Uncontrolled protein attachment on NPs may bring unwanted impacts such as protein denaturation and aggregation. In contrast, controlled protein adsorption by optimal concentration, size, pH and surface modification of NPs may result in potential implementation of NPs as therapeutic agents especially for disaggregation of amyloid fibrils. Also, the effect of NPs-protein corona on reducing the cytotoxicity and clinical implications such as drug delivery, cancer therapy, imaging and diagnosis will be discussed. Validated correlative physicochemical parameters for NP-protein corona formation frequently derived from protein corona fingerprints of NPs which are more valid than the parameters obtained only on the base of NP features. This review may provide useful information regarding the potency as well as the adverse effects of NPs to predict their behavior in the in vivo experiments.Comment: 40 pages, 20 figure

Using fuzzy logic approach to predict work-related musculoskeletal disorders among automotive assembly workers

Background: Musculoskeletal disorders (MSDs) are considered an important health concern, particularly in automotive assembly industries. Evaluation of the effects of all MSDs risk factors is difficult due to its multifactorial nature. In addition, the risk factors cannot be detected accurately when they are only based on individual opinions. Thus, in this study, fuzzy logic tool was used to evaluate the combined effects of all risk factors on MSDs. Methods: This cross sectional study was conducted on 100 male workers in an automotive industry. Job satisfaction, job stress, job fatigue, and body posture were evaluated by a self-reported questionnaire. Body posture was evaluated using Rapid Entire Body Assessment (REBA). Primary data analysis on extracting the input variables of MATLAB was performed by SPSS 22, with a significant level of 0.05. T test, one-way Anova, and Pearson correlation analysis were used to extract the input variables for the fuzzy logic model. The results obtained from the Nordic questionnaire was selected as the output of the fuzzy model. Fuzzy logic assessment was performed using MATLAB software version 7.0. Results: There were significant differences between WMSDs factors, including job fatigue, strain, working posture, and the REBA final score, and pain in all limbs of the body (p<0.05). A significant difference was also found between working posture with wrist score (p<0.05). The findings on defuzzification showed a strong correlation between real and modelling results. Conclusion: The results showed that many factors such as posture, fatigue, and strain affect MSDs. Based on the obtained results, all categories of risk factors, including personal, psychosocial, and occupational, should be considered to predict MSDs, which can be achieved by a modeling approach. Keywords: Automotive industry; Fuzzy logic; Work-related musculoskeletal disorders

Genetic Diversity and Phylogenetic Study of Leishmania Species in Iran by Multilocus Sequence Typing

Background: Leishmaniasis is an important public health parasitic infection, which is endemic in many parts of the world, including Iran. We aimed to investigate genetic diversity and phylogenetic relationship among different Leishmania isolates using multilocus sequence typing (MLST). Methods: Totally, 41 isolates collected either from patients referred to Leishmaniasis Diagnostics and Treatment Center at Tehran University of Medical Sciences, Tehran, Iran or from animals during 2019-2021, were subjected to the study. They included L. major and L. tropica from human, L. infantum from canine, and L. turanica from rodents from different endemic foci of Iran analyzed using MLST including gp63, g6pdh, lack, nagt, and hsp70 genes. Results: A total of 5010 bps was analyzed from each isolate. The three targets, nagt, lack, and g6pdh, generated better topology comparing to the other genes. In the 44 isolates, 22 haplotypes (STs) were identified. Leishmania tropica contained the highest number of haplotypes (n=12) comparing to L. major (n=8), L. infantum (n=1) and L. turanica (n=1). All five genomic loci caused separation of Iranian Leishmania species at the species level, indicating conservation of these genes in the Leishmania parasite. Conclusion: The highest number of haplotypes belonged to L. tropica, indicating that the genetic diversity of this species is higher than that of L. major. It was further confirmed that the MLST is a suitable method to examine genetic variation of Leishmania parasites with respect to evolutionary and epidemiological studies

Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres

The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed Lf-Doxo-PMNSs for combined chemo-MF-PTT. The PMNSs were synthesized by hydrothermal method and their physicochemical properties were examined by FE-SEM, TEM, DLS, TGA, XRD investigations. The cytotoxicity of as-synthesized NPs against 4T1 cells was carried out by MTT and flow cytometry assays. Afterwards, the anti-cancer activities of as-synthesized Lf-Doxo-PMNSs on the tumor status, drug distribution and apoptosis mechanism were evaluated. The anti-cancer assays showed that Lf-Doxo-PMNSs significantly suppressed the cancer cell proliferation and tumor weight by prolonging drug availability and potential drug loading in tumor cells; whereas they showed a minimum cytotoxicity against non-cancerous cells. Likewise, combined chemo-MF-PTT using Lf-Doxo-PMNSs displayed the highest anti-cancer activity followed by combined chemo-PTT and combined chemo-MF therapy based on altering the apoptosis mechanism. Therefore, these results showed that combined chemo-MF-PTT based on Lf-Doxo-PMNSs can be used as a promising therapeutic platform with potential targeted drug delivery and high loading capacity features as well as reducing cancer drug resistance