Composição química e qualidade biológica da torta de colza (Brassica napus, L: )

The toxic effect of detoxified rapeseed meal obtained by 2 h lixiviation was studied in growing animals. The control diets provided 10% protein from casein, detoxified rapeseed and crude rapeseed. A fourth diet was prepared substituting half casein for detoxified rapeseed meal. Feed consumption, weight gain and protein efficiency ratio revealled good performance for all diets as compared to the crude meal. Protein efficiency ratio (PER) increased from 2,98 for detoxified rapeseed to 3,19 for casein. The lowest PER 2.16 for crude rapeseed was higher than that related by BALLESTER et alii (0,94). In animals fed crude rapeseed meal,no histological changes were detected. The detoxified material showed a satisfactory growth promoting capacity for the rats at the 10% protein dietary level. It did not cause either hypertrophy of the thyroid or histopathological damage to this gland. The present results seem to confirm the good quality of the protein of rapeseed presscake meal obtained from a low glucosinolate cultivar.A composição química e a qualidade biológica da torta de colza obtida da semente, variedade CTC-4, foram determinados. A farinha foi preparada me diante prensagem da semente e extração da gordura com solvente, lixiviada durante 2 horas, com água corrente na proporção de 1:5, e agitação constante, a fim de reduzir os níveis de glicosinolatos. O efeito tóxico foi observado através do peso dos órgãos e da histopatologia dos órgãos em experimento de 60 dias. A qualidade biológica da torta desintoxicada, ao nível de 5% e 10%, foi semelhante ao da caseína (PER controle 3,18 vs 3,08, 5% e 2,98, 10%). O PER da torta crua foi de 2,28. Os ratos que receberam a farinha crua tiveram órgãos maiores. As tireóides dos ratos submetidos as dietas 2 e 3, não demonstraram alterações que suspeitassem de um efeito bociogênico e as alterações ocorridas nas tireóides dos animais que receberam, D-4 foram semelhantes àquelas ocorridas nos grupos 2 e 3. Não houve danos célulares graves em relação ao fígado, os rins, o coração, baço e supra-renais para todos os grupos observados. O método de extração dos fatores tóxicos da colza foi eficiente de acordo com os resultados obtidos para o presente estudo

Assessment and treatment of malignant pleural effusions : visual analogue scale, ultrasound and drainage

This thesis consists of 3 studies: 1. Determination of the minimal important difference (MID) of the visual analogue scale for dyspnoea (VASD): Determining the MID of the VASD is essential to interpret the results of trials in patients with malignant pleural effusions (MPEs). Patients undergoing a pleural procedure assessed the change in their VASD and the degree of change in their symptoms on a Likert scale. The mean VASD in patients experiencing a ‘small but just worthwhile’ decrease in their symptoms is the MID for the VASD and was found to be 22mm (95% CI 16 - 27mm). 2. Development of a thoracic ultrasound septation score (TUSS): A TUSS is important for objectively assessing the degree of septation within a pleural effusion. An iterative process was used to demonstrate that degree of septation predicts clinical outcome, to identify candidate factors for inclusion in a TUSS and to determine which factors predicted the degree of septation. The final TUSS consisted of an assessment of the degree of homogeneity of septation distribution and number of septations at the most septated area. 3. Effect of an indwelling pleural catheter (IPC) versus standard care for relieving dyspnoea in patients with MPEs: the TIME2 randomised controlled trial (RCT). The objective of this unblinded RCT was to determine whether IPCs are more effective than chest drains and talc pleurodesis at relieving dyspnoea in patients with MPEs. 106 patients were randomised to either IPC or standard care in a 1:1 ratio. The primary outcome was daily VASD over 42 days post intervention. Dyspnoea improved in both groups with no significant difference in mean dyspnoea in the first 42 days (mean score: IPC 25mm (95% CI 19 – 30), standard care 24mm (95% CI 19 – 29)).EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Neutrinoless Double Beta Decay

This White Paper, prepared for the Fundamental Symmetries, Neutrons, and Neutrinos Town Meeting related to the 2023 Nuclear Physics Long Range Plan, makes the case for double beta decay as a critical component of the future nuclear physics program. The major experimental collaborations and many theorists have endorsed this white paper

Neutrinoless Double Beta Decay

International audienceThis White Paper, prepared for the Fundamental Symmetries, Neutrons, and Neutrinos Town Meeting related to the 2023 Nuclear Physics Long Range Plan, makes the case for double beta decay as a critical component of the future nuclear physics program. The major experimental collaborations and many theorists have endorsed this white paper

Neutrinoless Double Beta Decay

This White Paper, prepared for the Fundamental Symmetries, Neutrons, and Neutrinos Town Meeting related to the 2023 Nuclear Physics Long Range Plan, makes the case for double beta decay as a critical component of the future nuclear physics program. The major experimental collaborations and many theorists have endorsed this white paper

Neutrinoless Double Beta Decay

This White Paper, prepared for the Fundamental Symmetries, Neutrons, and Neutrinos Town Meeting related to the 2023 Nuclear Physics Long Range Plan, makes the case for double beta decay as a critical component of the future nuclear physics program. The major experimental collaborations and many theorists have endorsed this white paper

Neutrinoless Double Beta Decay

This White Paper, prepared for the Fundamental Symmetries, Neutrons, and Neutrinos Town Meeting related to the 2023 Nuclear Physics Long Range Plan, makes the case for double beta decay as a critical component of the future nuclear physics program. The major experimental collaborations and many theorists have endorsed this white paper