223 research outputs found
Text and Interaction: A Performance Analysis Written in Present Evaluations of Pedagogy Students in the Distance Mode
This study aims to verify the use and mastery of linguistic knowledge in the writing process of Pedagogy students, in the form of Distance Education. The methodology was based on an exploratory analysis of texts produced in the face-to-face assessments that occurred in the first half of 2017. In the analysis of the answers, a descriptive graph of the errors and inadequacies observed was presented. The results show the commitment of writing to the meaning of the text, since this is a result of it. With this study, it was noticed that the university students have presented difficulties in expressing, in writing, their thoughts, their understandings and their opinions in an adequate and coherent way. Therefore, in order to minimize the anxiety experienced by these students at the time of writing, it is suggested that through the Instrumental Portuguese class, which part of the curriculum is, the linguistic aspects responsible for the production of meaning in texts and the interaction of the interlocutors. In order to meet the needs of undergraduate students, in the specific case of Pedagogy, since it concerns the training of teachers, professionals who will work in the literacy of children and young people and need to prioritize knowledge about language, reading and writing of these students
Analysis of histological frequency and pediatric cancer in Rondônia, Western Amazonia (Brazil)
Objective:Describe the histological and cancer frequency in children and adolescents attended at the Hospital de Base Dr. Ary Pinheiro and the Hospital de Barretos / Rondônia, Western Amazonia, in the years 2014 and 2015. Method: This is a descriptive, quantitative and transverse study. We used a structured instrument containing a series of variables, such as gender, age, histological types, more frequent neoplasms, lymphomas, leukemias, among others. We asked The Comitê de Ética em Pesquisa em Seres Humanos (Research Ethics Committee) to dispense the Informed Consent Form because the study did not require intervention on the patient or collection of biological material, and no possibility of constraints on patients and their relatives. Results: From 75 cases, 32 (42.7%) were female and 43 (57.3%) were male. Regarding the distribution of patients according to the age group, 21 (28.0%) were younger than 4 years, 12 (16.0%), 5 to 9 years, 17 (22.6%) from 10 to 14 and 25 (33.4%) from 15 to 19. The most frequent histological types by gender were leukemias of myeloproliferative diseases and myelodysplastic diseases with 30% and 50% new cases in the period, followed by lymphomas and reticuloendothelial neoplasms with 16.65% and 20, 0% of the histological types in the period. Leukemia in the hematopoietic and reticuloendothelial system (C42) is the most frequent cancer in both, female and male gender, with 47.5% of cancers in the biennium. The second group of cancers in children from 0 to 19 years old and location of the primary tumor is the encephalon carcinoma (C71), with 11.25% of the new cases. Conclusions: The results presented with their proper nuances are in agreement with the data of studies carried out in Brazil and in other countries
PRÓS E CONTRAS DA GLOBALIZAÇÃO
A PRESENTE OBRA TEM COMO PREMISSA PRINCIPAL INTRODUZIR O DEBATE QUE TEM SIDO FLAGRANTE, PRINCIPALMENTE NA ÚLTIMA DÉCADA DO SÉCULO XX, SOBRE O FENÔMENO DA
GLOBALIZAÇÃO. PARA TANTO, OS AUTORES CONSULTARAM UMA VASTA BIBLIOGRAFIA DE DOIS GRANDES GRUPOS QUE DISCUTEM A GLOBALIZAÇÃO EM LADOS OPOSTOS, OS GLOBALISTAS E OS CÉTICOS. PASSANDO POR MUITOS TEMAS IMPORTANTES PARA A DISCUSSÃO DO FENÔMENO GLOBALIZANTE, IDENTIFICAM-SE AS VISÕES DOS CÉTICOS E DOS GLOBALISTAS SOBRE CADA ASSUNTO TRATADO DE UMA MANEIRA QUE TORNA FÁCIL A COMPREENSÃO POR PARTE DO LEITOR
Prolonged caffeine intake decreases alveolar bone damage induced by bingelike ethanol consumption in adolescent female rats
Ethanol consumption has been reported to negatively impact on periodontal disease. In particular, oral cavity disorders occur upon ethanol exposure during adolescence, a life period associated with particular patterns of short and intense (‘binge-like’) ethanol consumption that is most deleterious to oral health. The hazardous central effects of ethanol have been linked to the overfunction of adenosine receptors, which are antagonized by caffeine, a bioactive substance present in numerous natural nutrients, which can also modify bone metabolism. The aim of this study was to investigate the effects of caffeine on alveolar bone damage induced by an ethanol binge drinking paradigm during adolescence. Female Wistar rats (35 days old; n = 30) were allocated to six groups: control (vehicle), ethanol (3 g/kg/day; 3 days On-4 days Off challenge), caffeine (10 mg/kg/day), caffeine plus ethanol, SCH58261 (0.1 mg/kg/day, an antagonist of A2A receptors), and SCH58261 plus ethanol. Bone micromorphology and vertical bone loss were analyzed by computed microtomography. Our data showed that ethanol binge drinking reduced alveolar bone quality, with repercussion on alveolar bone size. This ethanolinduced alveolar bone deterioration was abrogated upon treatment with caffeine, but not with SCH58261. This shows that caffeine prevented the periodontal disorder caused by ethanol binge drinking during adolescence, an effect that was not mediated by adenosine A2A receptor blockad
Impact of adhesive and photoactivation method on sealant integrity and polymer network formation
We evaluated the influence of photoactivation method and hydrophobic resin (HR) application on the marginal and internal adaptation, hardness (KHN), and crosslink density (CLD) of a resin-based fissure sealant. Model fissures were created in bovine enamel fragments (n = 10) and sealed using one of the following protocols: no adhesive system + photoactivation of the sealant using continuous light (CL), no adhesive system + photoactivation of the sealant using the soft-start method (SS), HR + CL, or HR + SS. Marginal and internal gaps and KHN were assessed after storage in water for 24 h. The CLD was indirectly assessed by repeating the KHN measurement after 24 h of immersion in 100% ethanol. There was no difference among the samples with regard to marginal or internal adaptation. The KHN and CLD were similar for samples cured using either photoactivation method. Use of a hydrophobic resin prior to placement of fissure sealants and curing the sealant using the soft-start method may not provide any positive influence on integrity or crosslink density
Galectin-3 negatively regulates the frequency and function of CD4+CD25+Foxp3+ regulatory T cells and influences the course of Leishmania major infection
Galectin-3, an endogenous glycan-binding protein, plays essential roles during microbial infection by modulating innate and adaptive immunity. However, the role of galectin-3 within the CD4+CD25+Foxp3+ T regulatory (TREG) cell compartment has not yet been explored. Here, we found, in a model of Leishmania major infection, that galectin-3 deficiency increases the frequency of peripheral TREG cells both in draining lymph nodes (LNs) and sites of infection. These observations correlated with an increased severity of the disease, as shown by increased footpad swelling and parasite burden. Galectin-3-deficient (Lgals3−/−) TREG cells displayed higher CD103 expression, showed greater suppressive capacity, and synthesized higher amounts of IL-10 compared with their wild-type (WT) counterpart. Furthermore, both TREG cells and T effector (TEFF) cells from Lgals3−/− mice showed higher expression of Notch1 and the Notch target gene Hes-1. Interestingly, Notch signaling components were also altered in both TREG and TEFF cells from uninfected Lgals3−/− mice. Thus, endogenous galectin-3 regulates the frequency and function of CD4+CD25+Foxp3+ TREG cells and alters the course of L. major infection.Fil: Fermino, Marise L.. Universidade de Sao Paulo; BrasilFil: Dias, Fabrício C.. Universidade de Sao Paulo; BrasilFil: Lopes, Carla D.. Universidade de Sao Paulo; BrasilFil: Souza, Maria A.. Universidade de Sao Paulo; BrasilFil: Cruz, Ângela K.. Universidade de Sao Paulo; BrasilFil: Liu, Fu Tong. University of California at Davis; Estados UnidosFil: Chammas, Roger. Universidade de Sao Paulo; BrasilFil: Roque Barreira, Maria C.. Universidade de Sao Paulo; BrasilFil: Rabinovich, Gabriel Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; ArgentinaFil: Bernardes, Emerson S.. Universidade de Sao Paulo; Brasi
How manipulating task constraints in small-sided and conditioned games shapes emergence of individual and collective tactical behaviours in football: A systematic review
Background:
Small-Sided and Conditioned Games are characterised by modifications of field dimensions, number of players, rules of the game, manipulations used to shape the key task constraints that performers need to satisfy in practice. Evidence has already demonstrated the importance of designing practice to enhance understanding of tactical behaviours in football, but there is a lack of information about how coaches can manipulate task constraints to support tactical learning.
Objective:
To investigate which task constraints have been most often manipulated in studies of SSCGs; and what impact each manipulation had on emerging tactical behaviours, technical–tactical actions, and positional relationships between players.
Methods:
PubMed, Web of Science, Scielo, and Academic Google databases were searched for relevant reports without time limits. The criteria adopted for inclusion were: a) studies performed with football players; b) studies that included SSCGs as an evaluation method; c) studies that investigated tactical behaviours in SSCGs; and d), articles in English and Portuguese.
Results:
The electronic database search included 24 articles in the review. Of these, five manipulated field dimensions, six manipulated number of players involved, five manipulated field dimensions and number of players, five used different scoring targets, two altered the number of players and scoring target, and one manipulated the number of players, field dimension, and scoring target.
Conclusion:
Among the task constraints analyzed in this systematic review, manipulation of number of players and playing field dimensions concomitantly occurred most frequentl
How manipulating task constraints in small-sided and conditioned games shapes emergence of individual and collective tactical behaviours in football: A systematic review
Background:
Small-Sided and Conditioned Games are characterised by modifications of field dimensions, number of players, rules of the game, manipulations used to shape the key task constraints that performers need to satisfy in practice. Evidence has already demonstrated the importance of designing practice to enhance understanding of tactical behaviours in football, but there is a lack of information about how coaches can manipulate task constraints to support tactical learning.
Objective:
To investigate which task constraints have been most often manipulated in studies of SSCGs; and what impact each manipulation had on emerging tactical behaviours, technical–tactical actions, and positional relationships between players.
Methods:
PubMed, Web of Science, Scielo, and Academic Google databases were searched for relevant reports without time limits. The criteria adopted for inclusion were: a) studies performed with football players; b) studies that included SSCGs as an evaluation method; c) studies that investigated tactical behaviours in SSCGs; and d), articles in English and Portuguese.
Results:
The electronic database search included 24 articles in the review. Of these, five manipulated field dimensions, six manipulated number of players involved, five manipulated field dimensions and number of players, five used different scoring targets, two altered the number of players and scoring target, and one manipulated the number of players, field dimension, and scoring target.
Conclusion:
Among the task constraints analyzed in this systematic review, manipulation of number of players and playing field dimensions concomitantly occurred most frequentl
ESTUDO DA CONTRIBUIÇÃO INERCIAL E DE AMORTECIMENTO DE LINHAS DE ANCORAGEM NO MOVIMENTO DE MONOBOIAS
In offshore oil production activities, monobuoys comprise oceanic terminals used by offloading ships to control the oil transference to the coast. They are relatively small structures, with accentuated dynamic responses when submitted to wave forces. Due to their lower inertia when compared with other types of floating systems, their mooring lines and risers lines may contribute directly with its static and dynamic behavior, evidencing a structural and hydrodynamic coupling between monobuoy and lines. In the search of an analysis methodology that may take advantage on both coupled and uncoupled formulations, this work presents procedures to evaluate, based on coupled simulations, the inertial and damping contribution of the mooring lines and risers into the monobuoy’s responses. These values may be inserted as input parameters into a calibrated uncoupled simulation to obtain dynamic responses with higher accuracy and lower computational cost. This work will present a case study of a standard monobuoy, with 9 mooring lines, located into a 90 meter water depth, comparing the motions provided by coupled and uncoupled simulations, with and without the proposed calibration procedure, and assessing the computational costs
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