729 research outputs found
Darwinism and Organizational Ecology: A Reply to Reydon and Scholz
In an earlier article published in this journal I challenge Reydon and Scholz's (2009) claim that Organizational Ecology is a non-Darwinian program. In this replay to Reydon and Scholz's subsequent response, I clarify the difference between our two approaches denoted by an emphasis her on the careful application of core Darwinian principles and an insistence by Reydon and Scholz on direct biological analogies. On a substantive issue, they identify as being the principle problem for Organizational Ecology, namely, the inability to identify replicators and interactors "of the right sort" in the business domain; this is also shown to be easily addressed with reference to empirical studies of business populations.Peer reviewedFinal Accepted Versio
Replica symmetry breaking in an adiabatic spin-glass model of adaptive evolution
We study evolutionary canalization using a spin-glass model with replica
theory, where spins and their interactions are dynamic variables whose
configurations correspond to phenotypes and genotypes, respectively. The spins
are updated under temperature T_S, and the genotypes evolve under temperature
T_J, according to the evolutionary fitness. It is found that adaptation occurs
at T_S < T_S^{RS}, and a replica symmetric phase emerges at T_S^{RSB} < T_S <
T_S^{RS}. The replica symmetric phase implies canalization, and replica
symmetry breaking at lower temperatures indicates loss of robustness.Comment: 5pages, 2 figure
Genetic Polymorphism in Evolving Population
We present a model for evolving population which maintains genetic
polymorphism. By introducing random mutation in the model population at a
constant rate, we observe that the population does not become extinct but
survives, keeping diversity in the gene pool under abrupt environmental
changes. The model provides reasonable estimates for the proportions of
polymorphic and heterozygous loci and for the mutation rate, as observed in
nature
Entropic Sampling and Natural Selection in Biological Evolution
With a view to connecting random mutation on the molecular level to
punctuated equilibrium behavior on the phenotype level, we propose a new model
for biological evolution, which incorporates random mutation and natural
selection. In this scheme the system evolves continuously into new
configurations, yielding non-stationary behavior of the total fitness. Further,
both the waiting time distribution of species and the avalanche size
distribution display power-law behaviors with exponents close to two, which are
consistent with the fossil data. These features are rather robust, indicating
the key role of entropy
Shaping Robust System through Evolution
Biological functions are generated as a result of developmental dynamics that
form phenotypes governed by genotypes. The dynamical system for development is
shaped through genetic evolution following natural selection based on the
fitness of the phenotype. Here we study how this dynamical system is robust to
noise during development and to genetic change by mutation. We adopt a
simplified transcription regulation network model to govern gene expression,
which gives a fitness function. Through simulations of the network that
undergoes mutation and selection, we show that a certain level of noise in gene
expression is required for the network to acquire both types of robustness. The
results reveal how the noise that cells encounter during development shapes any
network's robustness, not only to noise but also to mutations. We also
establish a relationship between developmental and mutational robustness
through phenotypic variances caused by genetic variation and epigenetic noise.
A universal relationship between the two variances is derived, akin to the
fluctuation-dissipation relationship known in physics
Peramorphosis, an evolutionary developmental mechanism in neotropical bat skull diversity
Background
The neotropical leaf‐nosed bats (Chiroptera, Phyllostomidae) are an ecologically diverse group of mammals with distinctive morphological adaptations associated with specialized modes of feeding. The dramatic skull shape changes between related species result from changes in the craniofacial development process, which brings into focus the nature of the underlying evolutionary developmental processes.
Results
In this study, we use three‐dimensional geometric morphometrics to describe, quantify, and compare morphological modifications unfolding during evolution and development of phyllostomid bats. We examine how changes in development of the cranium may contribute to the evolution of the bat craniofacial skeleton. Comparisons of ontogenetic trajectories to evolutionary trajectories reveal two separate evolutionary developmental growth processes contributing to modifications in skull morphogenesis: acceleration and hypermorphosis.
Conclusion
These findings are consistent with a role for peramorphosis, a form of heterochrony, in the evolution of bat dietary specialists
Cooperative secretions facilitate host range expansion in bacteria
The majority of emergent human pathogens are zoonotic in origin, that is, they can transmit to humans from other animals. Understanding the factors underlying the evolution of pathogen host range is therefore of critical importance in protecting human health. There are two main evolutionary routes to generalism: organisms can tolerate multiple environments or they can modify their environments to forms to which they are adapted. Here we use a combination of theory and a phylogenetic comparative analysis of 191 pathogenic bacterial species to show that bacteria use cooperative secretions that modify their environment to extend their host range and infect multiple host species. Our results suggest that cooperative secretions are key determinants of host range in bacteria, and that monitoring for the acquisition of secreted proteins by horizontal gene transfer can help predict emerging zoonoses
Клінічний випадок “защемлення” колоноскопа в грижовому мішку у хворого з лівобічною пахвинно-калитковою грижею
The article adduces unique clinical case, clinical features, diagnosis and surgical treatment of colonoscope “jamming” in hernia sac in patients with left-side inguinal hernia are presented.В статье представлен уникальный клинический случай, особенности клиники, диагностики и хирургического лечения “ущемление” колоноскопа в грыжевом мешке больного с левосторонней пахово-мошоночной грыжей.У статті представлено унікальний клінічний випадок, особливості клініки, діагностики та хірургічного лікування “защемлення” колоноскопа в грижовому мішку у хворого з лівобічною пахвинно-калитковою грижею.
Topological reversibility and causality in feed-forward networks
Systems whose organization displays causal asymmetry constraints, from
evolutionary trees to river basins or transport networks, can be often
described in terms of directed paths (causal flows) on a discrete state space.
Such a set of paths defines a feed-forward, acyclic network. A key problem
associated with these systems involves characterizing their intrinsic degree of
path reversibility: given an end node in the graph, what is the uncertainty of
recovering the process backwards until the origin? Here we propose a novel
concept, \textit{topological reversibility}, which rigorously weigths such
uncertainty in path dependency quantified as the minimum amount of information
required to successfully revert a causal path. Within the proposed framework we
also analytically characterize limit cases for both topologically reversible
and maximally entropic structures. The relevance of these measures within the
context of evolutionary dynamics is highlighted.Comment: 9 pages, 3 figure
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