Is M82 X-1 Really An Intermediate-Mass Black Hole? X-ray Spectral and Timing Evidence

Ultra-luminous X-ray sources (ULXs) with apparent luminosities up to 100's of times the Eddington luminosity for a neutron star have been discovered in external galaxies. The existence of intermediate mass black holes has been proposed to explain these sources. We present evidence for an intermediate-mass black hole in the ULX M82 X-1 based on the spectral features and timing (QPO) properties of the X-radiation from this source. We revisited XMM Newton and RXTE data for M82 X-1 obtained in 2001 and 1997 for XMM and RXTE respectively. We show for these observations that the source is either in transition or in a high/soft state with photon spectral indices 2.1 and 2.7 respectively. We confirm the early determination of the QPO frequency ~ 55 mHz in this source by Strohmayer & Mushotzky and identify this as the low frequency QPO for the source. We apply a new method to determine the BH mass of M82 X-1. The method uses the index-QPO low frequency correlation that has been recently been established in galactic black hole candidates GRS 1915+105, XTE J1550-564, 4U 1630-47 and others. Using scaling arguments and the correlation derived from consideration of galactic BHs, we conclude that M82 X-1 is an intermediate BH with a mass of the order of 1000 solar masses.Comment: 7 pages and 3 figures. Accepted for publication in ApJ Letters, v.614, 2004, October 2

Ultrastructural characteristics of the lung of Melanophryniscus stelzneri stelzneri (Weyenberg, 1875) (Anura, Bufonidae)

The lung of the toad, Melanophryniscus stelzneri stelzneri was studied using scanning and transmission electron microscopy. In M.s.stelzneri the parenchyma forms a polygonal network arrangement, therefore the parenchyma is edicular. These spaces are delimited by the interconnection of third order septa which are covered by respiratory epithelium. Small patches of ciliated epithelium without goblet cells appear irregularly distributed on the septa. The respiratory epithelium consists of one type of pneumocyte, which shows characteristics of both type I and type II alveolar cells of higher vertebrates. The pneumocytes are irregular in shape and possess attenuated cytoplasmic processes, which spread around the capillaries to form the outer layer of the air-blood barrier. These cells contain different types of cytoplasmic bodies: electron dense bodies, multivesicular bodies and lamellar bodies. Dense bodies are probably the precursors of lamellar bodies and the multivesicular bodies are incorporated into the latter. Neuroepithelial bodies appear randomly distributed over the septa. These bodies are separated from the lumen of the lung by thin cytoplasmic processes of neighbouring pneumocytes. The air-blood barrier consists of three layers: epithelium, interstitial space and endothelium. The relatively simple pulmonary structure of M.s.stelzneri is due to a lower degree of partitioning of the pulmonary lumen in comparison to the lung of other bufonid anurans, could be correlated with a well developed cutaneous and buccopharingeal respiration. The testing of this hypothesis awaits further studies.Fil:Hermida, G.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina

Mixed-effects high-dimensional multivariate regression via group-lasso regularization

Linear mixed modeling is a well-established technique widely employed when observations possess a grouping structure. Nonetheless, this standard methodology is no longer applicable when the learning framework encompasses a multivariate response and high-dimensional predictors. To overcome these issues, in the present paper a penalized estimation procedure for multivariate linear mixed-effects models (MLMM) is introduced. In details, we propose to regularize the likelihood via a group-lasso penalty, forcing only a subset of the estimated parameters to be preserved across all components of the multivariate response. The methodology is employed to develop novel surrogate biomarkers for cardiovascular risk factors, such as lipids and blood pressure, from whole-genome DNA methylation data in a multi-center study. The described methodology performs better than current stateof- art alternatives in predicting a multivariate continuous outcome

Interference of diffraction and transition radiation and its application as a beam divergence diagnostic

We have observed the interference of optical diffraction radiation (ODR) and optical transition radiation (OTR) produced by the interaction of a relativistic electron beam with a micromesh foil and a mirror. The production of forward directed ODR from electrons passing through the holes and wires of the mesh and their separate interactions with backward OTR from the mirror are analyzed with the help of a simulation code. By careful choice of the micromesh properties, mesh-mirror spacing, observation wavelength and filter band pass, the interference of the ODR produced from the unperturbed electrons passing through the open spaces of the mesh and OTR from the mirror are observable above a broad incoherent background from interaction of the heavily scattered electrons passing through the mesh wires. These interferences (ODTRI) are sensitive to the beam divergence and can be used to directly diagnose this parameter. We compare experimental divergence values obtained using ODTRI, conventional OTRI, for the case when front foil scattering is negligible, and computed values obtained from transport code calculations and multiple screen beam size measurements. We obtain good agreement in all cases.Comment: 40 pages 18 Figures. accepted for publication in PRSTA

Espiritualidad ignaciana

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Alianza bíblica y regla religiosa. (Estudio histórico-salvífico de las Constituciones de la Compañía de Jesús)

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Pastoral, catequesis, liturgia

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