18 research outputs found

    Does transition from an unstable labour market position to permanent employment protect mental health? Results from a 14-year follow-up of school-leavers

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    <p>Abstract</p> <p>Background</p> <p>Having secure employment, in contrast to being unemployed, is regarded as an important determinant of health. Research and theories about the negative health consequences of unemployment indicated that transition from unemployment to a paid job could lead to improved health. The objective of this study was to test the hypothesis that obtaining permanent employment after being in an unstable labour market position protects mental health.</p> <p>Methods</p> <p>A 14-year follow-up of all graduates from compulsory school in an industrial town in northern Sweden was performed at ages 16, 18, 21 and 30 years. Complete data on the cohort were collected for 1044 individuals with the aid of a comprehensive questionnaire. The response rate was 96.4%. The health measurement used in this study was the psychological symptoms analysed by multivariate logistic regression. Those who obtained permanent employment were the focus of the analysis. This group consisted of people who were in an unstable labour market position for a year or more between the ages of 25 and 29, and who had acquired a permanent job one year before and at the time of the investigation.</p> <p>Results</p> <p>After controlling for gender as well as for an indicator of health-related selection, possible confounders and mediators, an association was found between the lower probability of psychological symptoms and obtaining permanent employment (OR = 0.35, 95% CI 0.19–0.63) as well as having permanent employment (OR = 0.22, 95% CI 0.10–0.51).</p> <p>Conclusion</p> <p>Our findings suggest that transition from an unstable labour market position to permanent employment could be health-promoting, even after controlling for possible confounders and mediators, as well as for an indicator of health-related selection. However, as there are few studies in the field, there is a need for more longitudinal studies in order to further analyse the relationship and to examine possible explanations. The policy implication of our study is that the transformation of unstable labour market positions into permanent employment could contribute to better public health.</p

    Aging Alters Functionally Human Dermal Papillary Fibroblasts but Not Reticular Fibroblasts: A New View of Skin Morphogenesis and Aging

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    Understanding the contribution of the dermis in skin aging is a key question, since this tissue is particularly important for skin integrity, and because its properties can affect the epidermis. Characteristics of matched pairs of dermal papillary and reticular fibroblasts (Fp and Fr) were investigated throughout aging, comparing morphology, secretion of cytokines, MMPs/TIMPs, growth potential, and interaction with epidermal keratinocytes. We observed that Fp populations were characterized by a higher proportion of small cells with low granularity and a higher growth potential than Fr populations. However, these differences became less marked with increasing age of donors. Aging was also associated with changes in the secretion activity of both Fp and Fr. Using a reconstructed skin model, we evidenced that Fp and Fr cells do not possess equivalent capacities to sustain keratinopoiesis. Comparing Fp and Fr from young donors, we noticed that dermal equivalents containing Fp were more potent to promote epidermal morphogenesis than those containing Fr. These data emphasize the complexity of dermal fibroblast biology and document the specific functional properties of Fp and Fr. Our results suggest a new model of skin aging in which marked alterations of Fp may affect the histological characteristics of skin

    Housing tenure, housing wealth and subjective wellbeing in Australia: The case of unemployment

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    Item does not contain fulltextLike in many other western countries, the Australian welfare state is under pressure. The growing reliance on private insurance by means of accumulated wealth leads to a more prominent role for housing tenure and housing wealth, which is the most important source of wealth for most Australian households. The literature shows that unemployment leads to direct income losses and increased feelings of insecurity. Homeownership - as a stable basis for the private self, - and family and housing wealth - as a possible income-maintenance source, - have the potential to reinforce feelings of security and to supplement income. We research this issue with the Australian HILDA panel, waves 1-14 (2001-2015) and use panel fixed-effects analysis. Through following persons over time and researching their changes in subjective wellbeing when experiencing or not experiencing unemployment we can see whether housing tenure and housing wealth provide a potential buffer. We find that the negative effect of unemployment on subjective wellbeing is stronger for tenants than for homeowners. We do not find consistent effects for housing wealth as a buffer mitigating the negative life event of unemployment

    Mesenchymal Stem Cells in Wound Repair, Tissue Homeostasis, and Aging

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    Polarographisches Schrifttum

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