561 research outputs found

    DATforDCEMRI: An R Package for Deconvolution Analysis and Visualization of DCE-MRI Data

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    Numerical deconvolution is a powerful mathematical operation that can be used to extract the impulse response function of a linear, time-invariant system. We have found this method to be useful for preliminary analysis of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) data, capable of quickly producing voxel-wise parametric maps describing the heterogeneity of contrast agent kinetics over the entire field of view, typically comprising tens of thousands of voxels. The statistical programming language R is well suited for this type of analysis and when combined with LATEX, via Sweave, allows one to perform all calculations and generate a report with a single script. The purpose of this manuscript is to describe the R package DATforDCEMRI, a Deconvolution Analysis Tool for DCE-MRI contrast agent concentration vs. time data, which allows the user to perform kinetic deconvolution analysis and visualize/explore the resulting voxel-wise parametric maps and associated data

    Low-energy electron effects on tensile modulus and infrared transmission properties of a polypyromellitimide film

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    Infrared (IR) spectroscopy and tensile modulus testing were used to evaluate the importance of experimental procedure on changes in properties of pyromellitic dianhydride-p,p prime-oxydianiline film exposed to electron radiation. The radiation exposures were accelerated, approximate equivalents to the total dose expected for a 30 year mission in geosynchronous Earth orbit. The change in the tensile modulus depends more on the dose rate and the time interval between exposure and testing than on total dose. The IR data vary with both total dose and dose rate. A threshold dose rate exists below which reversible radiation effects on the IR spectra occur. Above the threshold dose rate, irreversible effects occur with the appearance of a new band. Post-irradiation and in situ IR absorption bands are significantly different. It is suggested that the electron radiation induced metastable, excites molecular states

    Transgenic Arabidopsis Gene Expression System

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    The Transgenic Arabidopsis Gene Expression System (TAGES) investigation is one in a pair of investigations that use the Advanced Biological Research System (ABRS) facility. TAGES uses Arabidopsis thaliana, thale cress, with sensor promoter-reporter gene constructs that render the plants as biomonitors (an organism used to determine the quality of the surrounding environment) of their environment using real-time nondestructive Green Fluorescent Protein (GFP) imagery and traditional postflight analyses

    Paper Session II-C - The Space Life Sciences Lab at the Kennedy Space Center: A Critical Facility for Future Space Flight

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    On November 19, 2003, Jim Kennedy, KSC Center Director, Winston Scott, former Astronaut and Director of the Florida Space Authority, Dr. Sam Durrance, Director of the Florida Space Research Institute, and Lt. Governor Toni Jennings, dedicated the Space Life Sciences Lab at the Kennedy Space Center. The SLS Lab is a world-class laboratory with all the capability and systems necessary to host International Space Station experiment processing as well as associated biological and life sciences research. Areas include Biotechnology, Microgravity, Space Agriculture, Biomedicine, Conservation Biology, and Microbial Ecology. This unique facility was constructed under a partnership between the State and NASA and provides the capability for researchers from the research consortium led by FSRI and the University of Florida to work closely with NASA researchers and payload developers to make fundamental advances in our understanding of biological systems and lay the ground work for long duration human space missions. This paper describes the unique partnerships, goals, operating capabilities and initial research activities of this important and unique research facility

    Doing Trust and Crisis Communication. Narratives of the 2021 Explosion in the Chempark Leverkusen

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    According to governmental recommendations and scholarship concerning crisis communication, which have emerged from the 1980s onwards, an important characteristic of successful disaster-related crisis communication is its capacity for developing or restoring trust. This article demonstrates how, in the aftermath of a tank farm explosion on 27 July 2021 in the waste incineration plant Chem-park in Leverkusen, the managing company, Currenta, engaged in crisis communication in a way that can indeed be interpreted as a form of ‘doing trust.’ By offering a discourse analysis of the statements published by Currenta on a newly created info page and its Twitter account, the paper explores the emergence of a specific crisis narrative connected to that aim. Our study shows how Currenta’s crisis narrative depicted the company as trustworthy by referring to its attempts at reflecting the values of integrity, transparency and (willingness to) dialogue. We situate these attempts in the context of competing narratives which, disseminated by other actors such as journalists, environmental activists and individual social media users, ‘revealed’ an alleged deceptiveness of the company and presented it as untrustworthy

    Oblivia mosaic: Voices on Forgetting, Performing, Transmitting

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    “Oblivia Mosaic” was created by the team members of the international performance company Oblivia. In this text, as well as in Oblivia’s way of devising performances, the individual meets the collective in the process where grand ideas are introduced in a minimalist disguise with a splash of humour. In 2020, the Helsinki-based company celebrates its 20th anniversary. Anna-Maija TerĂ€vĂ€: Matkalla Unholaan Alice Ferl: Many ones Annika Tudeer: Bodies memories Meri Ekola: Valo nousee kun pimeys on tiivistynyt tarpeeksi Yiran Zhao: Visible music Timo Fredriksson: Let's be dishonest &nbsp
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