98 research outputs found

    3D KINEMATIC AND KINETIC ANALYSIS OF JAVELIN THROWING PERFORMANCE

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    Major studies on javelin throwing have focused more recently on kinematics studies, in two, and later, in three dimensions (3D), especially to analyse high performances (Bartlell & Best, 1988). However, there is a lack of literature reporting on kinetics data in javelin throwing event (Bartonietz, 2000). The main objective of this study is to develop a 3D kinematics and kinetics analysis of the final release phase of the javelin throw to explain javelin throwing performance

    Evolution of the levels of human leukocyte antigen G (HLA-G) in Beninese infant during the first year of life in a malaria endemic area : using latent class analysis

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    Background: HLA-G, a non-classical HLA class I antigen, is of crucial interest during pregnancy by inhibiting maternal immune response. Its role during infections is discussed, and it has been described that high levels of soluble HLA-G during childhood increase the risk of malaria. To explore more precisely interactions between soluble HLA-G and malaria, latent class analysis was used to test whether distinct sub-populations of children, each with distinctive soluble HLA-G evolutions may suggest the existence of groups presenting variable malaria susceptibility. Method: A study was conducted in Benin from 2010 to 2013 and 165 children were followed from birth to 12 months. Evolution of soluble HLA-G was studied by the latent class method. Results: Three groups of children were identified: one with consistently low levels of soluble HLA-G during follow-up, a second with very high levels and a last intermediate group. In all groups, low birth weight, high number of malaria infections and high exposure to malaria transmission were associated with high level of soluble HLA-G. Placental malaria was not. Presence of soluble HLA-G in cord blood increased the probability of belonging to the highest trajectory. Conclusion: These results, together with previous ones, confirm the important role of HLA-G in the individual susceptibility to malaria. Assaying soluble HLA-G at birth could be a good indicator of newborns more fragile and at risk of infections during childhood

    Evolution of the levels of human leukocyte antigen G (HLA-G) in Beninese infant during the first year of life in a malaria endemic area: using latent class analysis

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    Abstract Background: HLA-G, a non-classical HLA class I antigen, is of crucial interest during pregnancy by inhibiting maternal immune response. Its role during infections is discussed, and it has been described that high levels of soluble HLA-G during childhood increase the risk of malaria. To explore more precisely interactions between soluble HLA-G and malaria, latent class analysis was used to test whether distinct sub-populations of children, each with distinctive soluble HLA-G evolutions may suggest the existence of groups presenting variable malaria susceptibility. Method: A study was conducted in Benin from 2010 to 2013 and 165 children were followed from birth to 12 months. Evolution of soluble HLA-G was studied by the latent class method. Results: Three groups of children were identified: one with consistently low levels of soluble HLA-G during follow-up, a second with very high levels and a last intermediate group. In all groups, low birth weight, high number of malaria infections and high exposure to malaria transmission were associated with high level of soluble HLA-G. Placental malaria was not. Presence of soluble HLA-G in cord blood increased the probability of belonging to the highest trajectory. Conclusion: These results, together with previous ones, confirm the important role of HLA-G in the individual susceptibility to malaria. Assaying soluble HLA-G at birth could be a good indicator of newborns more fragile and at risk of infections during childhood

    Etude cinétique et stoechiométrique de la croissance de Rhodospirillum rubrum en photobioréacteur

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    CLERMONT FD-BCIU Sci.et Tech. (630142101) / SudocSudocFranceF

    Idiopathic Pulmonary Embolism in a case of Severe Family ANKRD26 Thrombocytopenia

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    Venous thrombosis affecting thrombocytopenic patients is challenging. We report the case of a woman affected by deep vein thrombosis and pulmonary embolism in a thrombocytopenic context leading to the discovery of a heterozygous mutation in the gene encoding ankyrin repeat domain 26 (ANKRD26) associated with a heterozygous factor V (FV) Leiden mutation. This woman was diagnosed with lower-limb deep vein thrombosis complicated by pulmonary embolism. Severe thrombocytopenia was observed. The genetic study evidenced a heterozygous FV Leiden mutation. Molecular study sequencing was performed after learning that her family had a history of thrombocytopenia. Previously described heterozygous mutation c-127C>A in the 5'untranslated region (5'UTR) of the ANKRD26 gene was detected in the patient, her aunt, and her grandmother. ANKRD26-related thrombocytopenia and thrombosis are rare. This is, to our knowledge, the first case reported in the medical literature. This mutation should be screened in patients with a family history of thrombocytopenia

    Travailleurs venus d'ailleurs

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    Depuis toujours, des travailleurs venus d'ailleurs se sont installés, au gré des nécessités économiques, dans les régions de France. Qu'ils soient arrivés des proches pays européens, de l'Afrique ou de continents lointains, ils ont uni leurs destins à leur terre d'adoption. Ce livre réunit les portraits de femmes et d'hommes, tous immigrés ou descendants d'immigrés en Midi-Pyrénées, réalisés par les deux photographes spécialisés dans le documentaire : Gilles Favier et Sara Jabbar-Allen qui est à l'initiative du projet. De brefs récits de vie accompagnent les images. L'historienne Laure Teulières replace ces témoignages dans une perspective d'ensemble. Un DVD rassemble des entretiens radiophoniques. À travers ces parcours individuels et familiaux, c'est presque un siècle d'histoire sociale qui surgit. Sur trois générations, ces paroles et ces visages disent la nécessité d'ancrer l'immigration dans la mémoire collective et de lui rendre sa juste place au sein d'une histoire partagée. Ils nous rappellent aussi que chaque vie est unique et restituent à cette population immigrée l'infinie variation des récits personnels

    Modeling Stability of Photoheterotrophic Continuous Cultures in Photobioreactors

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    International audienceContinuous cultures of the purple non-sulfur bacterium Rhodospirillum rubrum were grown in a cylindrical photobioreactor in photoheterotrophic conditions, using acetate as carbon source. A new kinetic and stoichiometric knowledge model was developed and its ability to simulate experimental results obtained under varying incident light fluxes and residence times is discussed. The model Post 2 accurately predicts the stable, unstable or oscillating behavior observed for the reactor productivity. In particular, the values of residence time corresponding to a sub-critical bifurcation with a typical hysteresis effect are calculated and analyzed. The robustness of the proposed model allows the engineering operating domain of the photobioreactor function to be set, and offers a promising tool for the design and control of such photoheterotrophic processes
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