Staphylococcal Toxic Shock Syndrome 2000–2006: Epidemiology, Clinical Features, and Molecular Characteristics

Circulating strains of Staphylococcus aureus (SA) have changed in the last 30 years including the emergence of community-associated methicillin-resistant SA (MRSA). A report suggested staphylococcal toxic shock syndrome (TSS) was increasing over 2000-2003. The last population-based assessment of TSS was 1986.Population-based active surveillance for TSS meeting the CDC definition using ICD-9 codes was conducted in the Minneapolis-St. Paul area (population 2,642,056) from 2000-2006. Medical records of potential cases were reviewed for case criteria, antimicrobial susceptibility, risk factors, and outcome. Superantigen PCR testing and PFGE were performed on available isolates from probable and confirmed cases.Of 7,491 hospitalizations that received one of the ICD-9 study codes, 61 TSS cases (33 menstrual, 28 non-menstrual) were identified. The average annual incidence per 100,000 of all, menstrual, and non-menstrual TSS was 0.52 (95% CI, 0.32-0.77), 0.69 (0.39-1.16), and 0.32 (0.12-0.67), respectively. Women 13-24 years had the highest incidence at 1.41 (0.63-2.61). No increase in incidence was observed from 2000-2006. MRSA was isolated in 1 menstrual and 3 non-menstrual cases (7% of TSS cases); 1 isolate was USA400. The superantigen gene tst-1 was identified in 20 (80%) of isolates and was more common in menstrual compared to non-menstrual isolates (89% vs. 50%, p = 0.07). Superantigen genes sea, seb and sec were found more frequently among non-menstrual compared to menstrual isolates [100% vs 25% (p = 0.4), 60% vs 0% (p<0.01), and 25% vs 13% (p = 0.5), respectively].TSS incidence remained stable across our surveillance period of 2000-2006 and compared to past population-based estimates in the 1980s. MRSA accounted for a small percentage of TSS cases. tst-1 continues to be the superantigen associated with the majority of menstrual cases. The CDC case definition identifies the most severe cases and has been consistently used but likely results in a substantial underestimation of the total TSS disease burden

A Crowded desert: Early results from survey and excavation of nomadic sites in north-west Qatar (poster)

This paper presents the results and preliminary conclusions of the 2016 season of the Crowded Desert Project, which aimed to find out about nomadic occupation and its relations with settled peoples in the region. Activities included extensive and intensive surveys and excavations in the area delimited by the areas of Umm al-Mā' and Mulayha in the north-west desert of the Qatar peninsula. Conclusions so far complement and expand the ideas developed during the pilot season of the project in 2015, and also provide finer chronological detail and a wider coverage of the area of research than before. The distribution of glass, metal, and pottery recovered showed important chronological differences in the patterns of occupation of the landscape. The paper also presents observed differences in the spatial distribution of features, showing how cairns (presumably pre-Islamic tombs), Islamic burials and cemeteries, and mosques and places of prayer (sing, musallā, pl. musallayāt) are distributed with respect to the tents and spaces habitation found. Finally, this paper introduces the first stratigraphic and geoarchaeological assessments undertaken in the area. Stratigraphic sequences are hard to find, and often nothing remains of them around any preserved structures. In cases where some have been found, their interpretation is restricted by their poor state of preservation and the constraints imposed by small trenches. A geoarchaeological programme is being developed in the hope of overcoming these problems and providing environmental information that might be useful for the understanding of the history of the region

Global developments in forensic geology

Forensic geology has developed in each country dependent on the history, political and social setting, anthropological influences and geology. The aim of this section is to provide a global overview of forensic geology, including the history, developments and future challenges in Africa, Asia, Australia, Canada, Europe, Middle East, Latin America and the Caribbean, Russia and Commonwealth Independent States (CIS), and USA

Cryptic diversity and ecosystem functioning : a complex tale of differential effects on decomposition

Marine ecosystems are experiencing accelerating population and species loss. Some ecosystem functions are decreasing and there is growing interest in the link between biodiversity and ecosystem functioning. The role of cryptic (morphologically identical but genetically distinct) species in this biodiversity–ecosystem functioning link is unclear and has not yet been formally tested. We tested if there is a differential effect of four cryptic species of the bacterivorous nematode Litoditis marina on the decomposition process of macroalgae. Bacterivorous nematodes can stimulate or slow down bacterial activity and modify the bacterial assemblage composition. Moreover, we tested if interspecific interactions among the four cryptic species influence the decomposition process. A laboratory experiment with both mono- and multispecific nematode cultures was conducted, and loss of organic matter and the activity of two key extracellular enzymes for the degradation of phytodetritus were assessed. L. marina mainly influenced qualitative aspects of the decomposition process rather than its overall rate: an effect of the nematodes on the enzymatic activities became manifest, although no clear nematode effect on bulk organic matter weight loss was found. We also demonstrated that species-specific effects on the decomposition process existed. Combining the four cryptic species resulted in high competition, with one dominant species, but without complete exclusion of other species. These interspecific interactions translated into different effects on the decomposition process. The species-specific differences indicated that each cryptic species may play an important and distinct role in ecosystem functioning. Functional differences may result in coexistence among very similar species