183 research outputs found

    Markov associativities

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    Airway Remodeling and Cardiac Arrest in Long-Distance Ski Races

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    Segmentation and Clustering of Textual Sequences: a Typological Approach

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    The long term goal of this research is to develop a program able to produce an automatic segmentation and categorization of textual sequences into discourse types. In this preliminary contribution, we present the construction of an algorithm which takes a segmented text as input and attempts to produce a categorization of sequences, such as narrative, argumentative, descriptive and so on. Also, this work aims at investigating a possible convergence between the typological approach developed in particular in the field of text and discourse analysis in French by Adam (2008) and Bronckart (1997) and unsupervised statistical learning

    Photovoltaic Systems and Net Metering in Greece

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    The latest measure for the development of photovoltaics in Greece utilizes the net-metering scheme. Under this scheme the energy produced by a PV system may be either consumed by the local loads or be injected to the grid. The final cost reported in an electricity bill depends upon the energy produced by the PV system, the energy absorbed from the grid and the energy injected to the grid. Consequently, the actual electricity consumption profile is important to estimate the benefit from the use of this renewable energy source. The state latest statistics in Greece for households reveal that the typical electrical consumption is 3750 kWh while 10244 kWh are consumed in the form of thermal energy. We adopt in our calculations the above amount of electrical energy but assume four different scenarios. These different hourly profiles are examined to study the effects of synchronization upon the final cost of energy. The above scenarios are applied to areas in different climate zones in Greece (Heraklion, Athens and Thessaloniki) to examine the dependence of the hourly profiles and the solar potential upon the financial data with respect to internal rate of return, payback times, net present value and the levelized cost of energy. These parameters are affected by the initial system cost and the financial parameters

    Reflexive Cones

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    Reflexive cones in Banach spaces are cones with weakly compact intersection with the unit ball. In this paper we study the structure of this class of cones. We investigate the relations between the notion of reflexive cones and the properties of their bases. This allows us to prove a characterization of reflexive cones in term of the absence of a subcone isomorphic to the positive cone of \ell_{1}. Moreover, the properties of some specific classes of reflexive cones are investigated. Namely, we consider the reflexive cones such that the intersection with the unit ball is norm compact, those generated by a Schauder basis and the reflexive cones regarded as ordering cones in a Banach spaces. Finally, it is worth to point out that a characterization of reflexive spaces and also of the Schur spaces by the properties of reflexive cones is given.Comment: 23 page

    Metabolomics improves the histopathological diagnosis of asphyxial deaths: an animal proof-of-concept model

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    The diagnosis of mechanical asphyxia remains one of the most difficult issues in forensic pathology. Asphyxia ultimately results in cardiac arrest (CA) and, as there are no specific markers, the differential diagnosis of primitive CA and CA secondary to asphyxiation relies on circumstantial details and on the pathologist experience, lacking objective evidence. Histological examination is currently considered the gold standard for CA post-mortem diagnosis. Here we present the comparative results of histopathology versus those previously obtained by 1H nuclear magnetic resonance (NMR) metabolomics in a swine model, originally designed for clinical purposes, exposed to two different CA causes, namely ventricular fibrillation and asphyxia. While heart and brain microscopical analysis could identify the damage induced by CA without providing any additional information on the CA cause, metabolomics allowed the identification of clearly different profiles between the two groups and showed major differences between asphyxiated animals with good and poor outcomes. Minute-by-minute plasma sampling allowed to associate these modifications to the pre-arrest asphyxial phase showing a clear correlation to the cellular effect of mechanical asphyxia reproduced in the experiment. The results suggest that metabolomics provides additional evidence beyond that obtained by histology and immunohistochemistry in the differential diagnosis of CA

    Clinical practice recommendations on the management of perioperative cardiac arrest: A report from the PERIOPCA Consortium

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    Background: Perioperative cardiac arrest is a rare complication with an incidence of around 1 in 1400 cases, but it carries a high burden of mortality reaching up to 70% at 30 days. Despite its specificities, guidelines for treatment of perioperative cardiac arrest are lacking. Gathering the available literature may improve quality of care and outcome of patients. Methods: The PERIOPCA Task Force identified major clinical questions about the management of perioperative cardiac arrest and framed them into the therapy population [P], intervention [I], comparator [C], and outcome [O] (PICO) format. Systematic searches of PubMed, Embase, and the Cochrane Library for articles published until September 2020 were performed. Consensus-based treatment recommendations were created using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system. The strength of consensus among the Task Force members about the recommendations was assessed through a modified Delphi consensus process. Results: Twenty-two PICO questions were addressed, and the recommendations were validated in two Delphi rounds. A summary of evidence for each outcome is reported and accompanied by an overall assessment of the evidence to guide healthcare providers. Conclusions: The main limitations of our work lie in the scarcity of good quality evidence on this topic. Still, these recommendations provide a basis for decision making, as well as a guide for future research on perioperative cardiac arrest

    Regulation of peripheral blood flow in Complex Regional Pain Syndrome: clinical implication for symptomatic relief and pain management

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    Background. During the chronic stage of Complex Regional Pain Syndrome (CRPS), impaired microcirculation is related to increased vasoconstriction, tissue hypoxia, and metabolic tissue acidosis in the affected limb. Several mechanisms may be responsible for the ischemia and pain in chronic cold CPRS. Discussion. The diminished blood flow may be caused by either sympathetic dysfunction, hypersensitivity to circulating catecholamines, or endothelial dysfunction. The pain may be of neuropathic, inflammatory, nociceptive, or functional nature, or of mixed origin. Summary. The origin of the pain should be the basis of the symptomatic therapy. Since the difference in temperature between both hands fluctuates over time in cold CRPS, when in doubt, the clinician should prioritize the patient's report of a persistent cold extremity over clinical tests that show no difference. Future research should focus on developing easily applied methods for clinical use to differentiate between central and peripheral blood flow regulation disorders in individual patients
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