142 research outputs found

    Minimal invasive surgery in craniostenosis

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    En el presente trabajo se describe la experiencia en craneoestenosis con cirugía mínimamente invasiva, evaluando el diseño y eficacia de un nuevo craneotomo en cadáveres así como su aplicación clínica en un caso de sinostósis sagital con instrumentación endoscópica. Este procedimiento es sin duda un gran recurso en el tratamiento de las craneoestenosis brindando los beneficios de la cirugía mínimamente invasiva, eliminando la necesidad de grandes incisiones, disminuyendo el sangrado quirúrgico, reduciendo estancia hospitalaria y disminuyendo la morbilidad operatoria In this paper, we describe the experience with the use of endoscopic craniofacial procedures, evaluating the design and the efficacy of a new craniotome in cadavers and his clinical application in a case of sagittal synostosis for an endoscopic assisted cranioplasty. This procedure is a great option in the treatment of craniosynostosis, giving the benefits of minimal invasive surgery and eliminating the needing of big incisions, long hospital stay and reducing the postoperative morbidit

    Iron bioavailability in two commercial cultivars of wheat: a comparison between wholegrain and white flour and the effects of nicotianamine and 2'-deoxymugineic acid on iron uptake into Caco-2 cells

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    Iron bioavailability in unleavened white and wholegrain bread made from two commercial wheat varieties was assessed by measuring ferritin production in Caco-2 cells. The breads were subjected to simulated gastrointestinal digestion and the digests applied to the Caco-2 cells. Although Riband grain contained a lower iron concentration than Rialto, iron bioavailability was higher. No iron was taken up by the cells from white bread made from Rialto flour or from wholegrain bread from either variety, but Riband white bread produced a small ferritin response. The results probably relate to differences in phytate content of the breads, although iron in soluble monoferric phytate was demonstrated to be bioavailable in the cell model. Nicotianamine, an iron chelator in plants involved in iron transport, was a more potent enhancer of iron uptake into Caco-2 cells than ascorbic acid or 2'-deoxymugineic acid, another metal chelator present in plants

    Meeting the Challenges Facing Wheat Production The Strategic Research Agenda of the Global Wheat Initiative

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    Wheat occupies a special role in global food security since, in addition to providing 20% of our carbohydrates and protein, almost 25% of the global production is traded internationally. The importance of wheat for food security was recognised by the Chief Agricultural Scientists of the G20 group of countries when they endorsed the establishment of the Wheat Initiative in 2011. The Wheat Initiative was tasked with supporting the wheat research community by facilitating col-laboration, information and resource sharing and helping to build the capacity to address chal-lenges facing production in an increasingly variable environment. Many countries invest in wheat research. Innovations in wheat breeding and agronomy have delivered enormous gains over the past few decades, with the average global yield increasing from just over 1 tonne per hectare in the early 1960s to around 3.5 tonnes in the past decade. These gains are threatened by climate change, the rapidly rising financial and environmental costs of fertilizer, and pesticides, combined with declines in water availability for irrigation in many regions. The international wheat research community has worked to identify major opportunities to help ensure that global wheat pro-duction can meet demand. The outcomes of these discussions are presented in this paper

    International Lower Limb Collaborative (INTELLECT) study : a multicentre, international retrospective audit of lower extremity open fractures

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    International Lower Limb Collaborative (INTELLECT) study: a multicentre, international retrospective audit of lower extremity open fractures

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    International lower limb collaborative (INTELLECT) study: a multicentre, international retrospective audit of lower extremity open fractures

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    Trauma remains a major cause of mortality and disability across the world1, with a higher burden in developing nations2. Open lower extremity injuries are devastating events from a physical3, mental health4, and socioeconomic5 standpoint. The potential sequelae, including risk of chronic infection and amputation, can lead to delayed recovery and major disability6. This international study aimed to describe global disparities, timely intervention, guideline-directed care, and economic aspects of open lower limb injuries
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