Carcinoma bronquiolo-alveolar en perro : un caso clínico. Diagnóstico y tratamiento quirúrgico

Se describe un caso clínico de un perro Staffordshire Bull Terrier macho de 2 años de edad que presentaba un historial de insuficiencia respiratoria. Tras la exploración física, se aprecia la existencia de un derrame pleural procediéndo-se a realizar diferentes pruebas diagnósticas para establecer su causa incluyendo la toracocentesis y cultivo bacteriológico, radiología y ecografía torácica. Se describe la vía de abordaje quirúrgico uti- lizada en este caso (esternotomía mediana); así como, la intervención de lobectomía a la que fue sometido el paciente. La pieza de extirpación quirúrgica fue remitida para su análisis histopatolóqico, confirmando el diagnóstico de carcinoma bronquiolo-alveolar primario de pulmón.A clinical case is described of a two year oid male Staffordshire Bull Terrier who was sent with a history of respiratory insufficiency. After a physical examination a pleural effusion was found preceeding various diagnostics such as thoracocentesis, bacteriological culture, thoracic radiographs and an ultrasound were issued to establish the cause. The surgical approach (medium esternotomy) and the lobectomy the patient suffered from are described. The surgical sample was sent to be analised histopatholoqícally, confirming the pulmonary primary bronchiolar-alvcolar carcinoma diagnostic

Enhancing MRI Reconstruction Efficiency Through Multi-GPU Parallelization

Dynamic cardiac MRI (cMRI) is essential for diagnosing cardiovascular diseases, demanding high resolution and image quality. However, achieving superior quality increases data volume and reconstruction time. To tackle this, we propose a solution using parallel imaging and Compressed Sensing (CS) with high-capacity computing devices (e.g., GPUs) for accelerated reconstruction of undersampled data. GPU mem- ory limitations, especially in 3D cMRI, present challenges. Our scalable approach splits the reconstruction problem and employs multiple GPUs (or multiple multi-core CPUs) to per- form multiple optimizations in parallel using the well-known NESTA algorithm, while preserving smoothness between ad- jacent frames in the temporal dimension. Preliminary results on 5D cMRI reconstruction show that our parallel proposal achieves equivalent reconstruction quality in less time, en- abling larger data processing and cost reduction with smaller, more affordable GPUs, as opposed to a single, highly expensive GPU. Moreover, the adoption of the OpenCLIPER frame- work eliminates proprietary GPU technologies. Exploration of adaptability to other sampling schemes opens new possibilities in this field.This work is partially supported by MINECO under grants TEC2017-82408-R, PRE2018-086922, and by the Agencia Estatal de Investigación under grants PID2020- 115339RB-I00 and TED2021-130090B-I00

The paradoxical relationship between emotion regulation and gambling-related cognitive biases

The funding agency is public and played no role in planning or executing this work, nor interfered with the collection and interpretation of data.Background Gambling behavior presents substantial individual variability regarding its severity, manifestations, and psychological correlates. Specifically, differences in emotion regulation, impulsivity, and cognitive distortions have been identified as crucial to describe individual profiles with implications for the prevention, prognosis, and treatment of gambling disorder (GD). Aims and method The aim of the present study was to investigate the associations of gambling-related cognitions (measured according to the GRCS model) with impulsivity (UPPS-P model) and emotion regulation (CERQ model), in a sample of 246 gamblers with different levels of gambling involvement, using mixed-effects modelling to isolate theoretically relevant associations while controlling for the potentially confounding effects of sociodemographic and clinical covariates. Results Affective/motivational dimensions of UPPS-P impulsivity positive urgency and sensation seeking, on the one hand, and CERQ emotion regulation strategies reappraisal, rumination and blaming others, on the other, independently and significantly predicted distorted gambling- related cognitions. Conclusions These results (a) reinforce the ones of previous studies stressing the relevance of emotional and motivational processes in the emergence of gambling-related cognitive distortions; and (b) replicate the seemingly paradoxical finding that gamblers use emotion regulation strategies customarily considered as adaptive (i.e. reappraisal) to strengthen and justify their biased beliefs about gambling outcomes and controllability.Supported by a grant from the Spanish Government (Ministerio de Economía y Competitividad, Secretaría de Estado de Investigación, Desarrollo e Innovación; Convocatoria 2017 de Proyectos I+D de Excelencia, Spain; co-funded by the Fondo Europeo de Desarrollo Regional, FEDER, European Union), with reference number PSI2017-85488-

The role of impulsivity in dropout from treatment for cigarette smoking

AbstractImpulsivity is a variable that has been associated with drug use. This study analyzes impulsivity from two different paradigms, one considering it as a trait and the other based on its behavioral correlates, such as disinhibition and impulsive decision-making in the treatment prognosis (maintain abstinence, relapse and dropout) of smokers after outpatient treatment. The participants in the study were 113 smokers who requested treatment for nicotine addiction. They were assigned to three groups according to whether or not they remained abstinent one month after beginning treatment; thus, group 1 was abstinent, group 2 had relapsed, and group 3 had dropped out of treatment. The participants filled out the Semi-structured Interview for Smokers, the Fargerström Test for Nicotine Dependence, the Temperament and Character Inventory-Revised (TCI-R) and the Delay Discounting Task (DDT). The Delay Discounting variable presents lower scores in the dropout group than in the relapse and abstinent groups, with the highest scores in the relapse group. Differences were also found on the Harm Avoidance (HA) variable, with lower scores in the dropout group compared to the relapse group. The importance of these results lies in the consideration of the smoker’s personality profile in order to prevent both dropout and relapse

Dynamics of magnetic assembly of binary colloidal structures

"This is an author-created, un-copyedited version of an article published in Europhysics Letters. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at 10.1209/0295-5075/111/37002."Magnetic field (MF)-directed assembly of colloidal particles provides a step towards the bottom-up manufacturing of smart materials whose properties can be precisely modulated by non-contact forces. Here, we study the MF-directed assembly in binary colloids made up of strong ferromagnetic and diamagnetic microparticles dispersed in ferrofluids. We present observations of the aggregation of pairs and small groups of particles to build equilibrium assemblies. We also develop a theoretical model capable of solving the aggregation dynamics and predicting the particle trajectories, a key factor to understand the physics governing the MF-directed assembly.The project MINECO FIS2013-41821-R (Spain) is acknowledged for financial support

Reconsidering the roots, structure, and implications of gambling motives: An integrative approach

The present study identified Social, Financial, and Fun/thrill-related gambling motives factors, but also a fourth factor in which some positive and negative reinforcement-based motives were grouped into a single and broader Affect regulation factor. This Affect regulation factor shared variance both with BIS and BAS-related measures, and was the only direct predictor of disordered gambling symptoms. The Fun/thrill factor was directly related to frequency of participation in high-arousal, skill-based games, and all factors were related to participation in lower-arousal, chance games (with Social motives negatively predicting both participation in the latter and total severity). In the SEM model, measures of BIS/BAS sensitivity were connected to gambling behavior only through gambling motives. Based on measures of items’ specificity, a shortened Spanish scale (the brief Gambling Motives Inventory, bGMI) is proposed to assess gambling motives in accordance with the observed 4-factor structure.This work is supported by a grant from the Spanish Government (Ministerio de Economía y Competitividad, Secretaría de Estado de Investigación, Desarrollo e Innovación; Convocatoria 2017 de Proyectos I+D de Excelencia, Spain; co-funded by the Fondo Europeo de Desarrollo Regional, FEDER, European Union), with reference number PSI2017-85488-P

Caffeinated Energy Drinks Boost Physical Performance In Several Sport Modalities: Should They Be Considered By Antidoping Authorities?

Caffeine has been consumed by man for centuries although the manner of consumption has varied among different geographical zones, according to the source of caffeine present in natural foods (e.g., coffee, tea, mate, guaraná, kola, etc.). By the end of XIX century, John S. Pemberton created the first non-natural caffeinated-beverage that contained caffeine form the kola nut. The use of this beverage – universally known as Coca-Cola- increased exponentially worldwide and favored the apparition of hundreds of commercial caffeinated drinks with similar characteristics. Although first energy drinks were marketed in Thailand in the 1970s, these drinks became widely popular when they were introduced in the European in the 1990s. Despite the commercial availability of numerous caffeinated beverages and foods, energy drinks have gained popularity in the last years, likely because they provide a higher dose of caffeine per serv

HBPEI-grafted carbon nanotubes for the effective retention of Pd2+ and Pt2+ through complexation

Hyperbranched poly(ethyleneimine) (HBPEI) molecules in solution present high capacity to form stable complexes with transition metal ions due to the large number of amino groups ready to form chelates. We grafted HBPEI molecules to a multi-walled carbon nanotube (MWCNT) surface through covalent bonding, preparing solid hybrids which retain the chemical properties of the free poly-alkylamine molecules. In this way, we are able to transfer the complexation capacity of such molecules to a solid material adequate to act as a high-capacity sorbent for metal transition ions. We tested the HBPEI/MWCNT hybrids for the retention of Pd2+ and Pt2+ and the retention values obtained are much larger than those previously reported with fast retention kinetics. The kinetics and the XPS analysis of the metal ion/HBPEI/ MWCNT ensemble indicate that the retention takes place through the formation of chelates with two or three nitrogen atoms and with Cl− anions as co-ligands. Moreover, the results allow us to tune the metal loading on the hybrids by controlling the solution conditions. This is important because the XPS valence band analysis demonstrates that metal complexation directly modifies the electronic behaviour of the carbon nanotubes, which supports the stable covalent bond between HBPEI molecules and MWCNT and opens the possibility for tuning the electronic properties of the tubes.The financial support of the MINECO (projects MAT2014- 60104-C2-1-R and MAT2014-60104-C2-2-R), FEDER program, Autonomous Regional Government (J. de Andalucía, group RNM342) and Programa de Fortalecimiento de la I+D+i from UGR is acknowledged. The technical assistance of Centre of Instrumental Facilities, STI, of the University of Jaén is also acknowledged