2,452 research outputs found

    Angular Dependent Magnetization Dynamics of Kagome Artificial Spin Ice Incorporating Topological Defects

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    We report angular-dependent spin-wave spectroscopy on kagome artificial spin ice made of large arrays of interconnected Ni80Fe20 nanobars. Spectra taken in saturated and disordered states exhibit a series of resonances with characteristic in-plane angular dependencies. Micromagnetic simulations allow us to interpret characteristic resonances of a two-step magnetization reversal of the nanomagnets. The dynamic properties are consistent with topological defects that are provoked via a magnetic field applied at specific angles. Simulations that we performed on previously investigated kagome artificial spin ice consisting of isolated nanobars show characteristic discrepancies in the spin wave modes which we explain by the absence of vertices.Comment: 14 pages and 5 figure

    Unravelling the health effects of fasting : a long road from obesity treatment to healthy life span increase and improved cognition

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    In recent years a revival of interest has emerged in the health benefits of intermittent fasting and long-term fasting, as well as of other related nutritional strategies. In addition to meal size and composition a new focus on time and frequency of meals has gained attention. The present review will investigate the effects of the main forms of fasting, activating the metabolic switch from glucose to fat and ketones (G-to-K), starting 12-16 h after cessation or strong reduction of food intake. During fasting the deactivation of mTOR regulated nutrient signalling pathways and activation of the AMP protein kinase trigger cell repair and inhibit anabolic processes. Clinical and animal studies have clearly indicated that modulating diet and meal frequency, as well as application of fasting patterns, e.g. intermittent fasting, periodic fasting, or long-term fasting are part of a new lifestyle approach leading to increased life and health span, enhanced intrinsic defences against oxidative and metabolic stresses, improved cognition, as well as a decrease in cardiovascular risk in both obese and non-obese subjects. Finally, in order to better understand the mechanisms beyond fasting-related changes, human studies as well as non-human models closer to human physiology may offer useful clue

    Observation of vortex-nucleated magnetization reversal in individual ferromagnetic nanotubes

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    The reversal of a uniform axial magnetization in a ferromagnetic nanotube (FNT) has been predicted to nucleate and propagate through vortex domains forming at the ends. In dynamic cantilever magnetometry measurements of individual FNTs, we identify the entry of these vortices as a function of applied magnetic field and show that they mark the nucleation of magnetization reversal. We find that the entry field depends sensitively on the angle between the end surface of the FNT and the applied field. Micromagnetic simulations substantiate the experimental results and highlight the importance of the ends in determining the reversal process. The control over end vortex formation enabled by our findings is promising for the production of FNTs with tailored reversal properties.Comment: 20 pages, 13 figure

    Platelet proteasome activity and metabolism is upregulated during bacterial sepsis

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    Dysregulation of platelet function can contribute to the disease progression in sepsis. The proteasome represents a critical and vital element of cellular protein metabolism in platelets and its proteolytic activity has been associated with platelet function. However, the role of the platelet proteasome as well as its response to infection under conditions of sepsis have not been studied so far. We measured platelet proteasome activity by fluorescent substrates, degradation of poly-ubiquitinated proteins and cleavage of the proteasome substrate Talin-1 in the presence of living E. coli strains and in platelets isolated from sepsis patients. Upregulation of the proteasome activator PA28 (PSME1) was assessed by quantitative real-time PCR in platelets from sepsis patients. We show that co-incubation of platelets with living E. coli (UTI89) results in increased degradation of poly-ubiquitinated proteins and cleavage of Talin-1 by the proteasome. Proteasome activity and cleavage of Talin-1 was significantly increased in α-hemolysin (HlyA)-positive E. coli strains. Supporting these findings, proteasome activity was also increased in platelets of patients with sepsis. Finally, the proteasome activator PA28 (PSME1) was upregulated in this group of patients. In this study we demonstrate for the first time that the proteasome in platelets is activated in the septic milieu

    Spin waves in CoFeB on ferroelectric domains combining spin mechanics and magnonics

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    Spin dynamics controlled by magnetoelastic coupling and applied electric fields might play a vital role in future developments of magnonics, i.e., the exploitation of spin waves for the transmission and processing of information. We have performed broadband spin-wave spectroscopy on a magnetostrictive CoFeB alloy grown on a ferroelectric BaTiO3 substrate causing elastic strain with a quasi-periodic modulation. We find characteristic eigenfrequencies and spin-wave modes with large group velocities and small damping. These results suggest bright perspectives for electric-field control of reprogrammable magnonics.Peer reviewe

    Imaging magnetic vortex configurations in ferromagnetic nanotubes

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    We image the remnant magnetization configurations of CoFeB and permalloy nanotubes (NTs) using x-ray magnetic circular dichroism photo-emission electron microscopy. The images provide direct evidence for flux-closure configurations, including a global vortex state, in which magnetization points circumferentially around the NT axis. Furthermore, micromagnetic simulations predict and measurements confirm that vortex states can be programmed as the equilibrium remnant magnetization configurations by reducing the NT aspect ratio.Comment: 14 pages, 4 figures, link to supplementary informatio

    Two-dimensional electron gas formation in undoped In[0.75]Ga[0.25]As/In[0.75]Al[0.25]As quantum wells

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    We report on the achievement of a two-dimensional electron gas in completely undoped In[0.75]Al[0.25]As/In[0.75]Ga[0.25]As metamorphic quantum wells. Using these structures we were able to reduce the carrier density, with respect to reported values in similar modulation-doped structures. We found experimentally that the electronic charge in the quantum well is likely due to a deep-level donor state in the In[0.75]Al[0.25]As barrier band gap, whose energy lies within the In[0.75]Ga[0.25]As/In[0.75]Al[0.25]As conduction band discontinuity. This result is further confirmed through a Poisson-Schroedinger simulation of the two-dimensional electron gas structure.Comment: 17 pages, 6 figures, to be published in J. Vac. Sci. Technol.

    Magnetization reversal of an individual exchange biased permalloy nanotube

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    We investigate the magnetization reversal mechanism in an individual permalloy (Py) nanotube (NT) using a hybrid magnetometer consisting of a nanometer-scale SQUID (nanoSQUID) and a cantilever torque sensor. The Py NT is affixed to the tip of a Si cantilever and positioned in order to optimally couple its stray flux into a Nb nanoSQUID. We are thus able to measure both the NT's volume magnetization by dynamic cantilever magnetometry and its stray flux using the nanoSQUID. We observe a training effect and temperature dependence in the magnetic hysteresis, suggesting an exchange bias. We find a low blocking temperature TB=18±2T_B = 18 \pm 2 K, indicating the presence of a thin antiferromagnetic native oxide, as confirmed by X-ray absorption spectroscopy on similar samples. Furthermore, we measure changes in the shape of the magnetic hysteresis as a function of temperature and increased training. These observations show that the presence of a thin exchange-coupled native oxide modifies the magnetization reversal process at low temperatures. Complementary information obtained via cantilever and nanoSQUID magnetometry allows us to conclude that, in the absence of exchange coupling, this reversal process is nucleated at the NT's ends and propagates along its length as predicted by theory.Comment: 8 pages, 4 figure

    Imaging stray magnetic field of individual ferromagnetic nanotubes

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    We use a scanning nanometer-scale superconducting quantum interference device to map the stray magnetic field produced by individual ferromagnetic nanotubes (FNTs) as a function of applied magnetic field. The images are taken as each FNT is led through magnetic reversal and are compared with micromagnetic simulations, which correspond to specific magnetization configurations. In magnetic fields applied perpendicular to the FNT long axis, their magnetization appears to reverse through vortex states, i.e.\ configurations with vortex end domains or -- in the case of a sufficiently short FNT -- with a single global vortex. Geometrical imperfections in the samples and the resulting distortion of idealized mangetization configurations influence the measured stray-field patterns.Comment: 14 pages, 4 figure

    Spin-current modulation and square-wave transmission through periodically stubbed electron waveguides

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    Ballistic spin transport through waveguides, with symmetric or asymmetric double stubs attached to them periodically, is studied systematically in the presence of a weak spin-orbit coupling that makes the electrons precess. By an appropriate choice of the waveguide length and of the stub parameters injected spin-polarized electrons can be blocked completely and the transmission shows a periodic and nearly square-type behavior, with values 1 and 0, with wide gaps when only one mode is allowed to propagate in the waveguide. A similar behavior is possible for a certain range of the stub parameters even when two-modes can propagate in the waveguide and the conductance is doubled. Such a structure is a good candidate for establishing a realistic spin transistor. A further modulation of the spin current can be achieved by inserting defects in a finite-number stub superlattice. Finite-temperature effects on the spin conductance are also considered.Comment: 19 pages, 8 figure
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