The NASA Space Station program plans

The design of a permanently manned space station is discussed. The role of the space shuttle, planning guidelines, international cooperation, and commercial possibilities are among the topics discussed

The influence of initial mass segregation on the runaway merging of stars

We have investigated the effect of initial mass segregation on the runaway merging of stars. The evolution of multi-mass, dense star clusters was followed by means of direct N-body simulations of up to 131.072 stars. All clusters started from King models with dimensionless central potentials of 3.0 <= W_0 <= 9.0. Initial mass segregation was realized by varying the minimum mass of a certain fraction of stars whose either (1) distances were closest to the cluster center or (2) total energies were lowest. The second case is more favorable to promote the runaway merging of stars by creating a high-mass core of massive, low-energy stars. Initial mass segregation could decrease the central relaxation time and thus help the formation of a high-mass core. However, we found that initial mass segregation does not help the runaway stellar merger to happen if the overall mass density profile is kept constant. This is due to the fact that the collision rate of stars is not increased due to initial mass segregation. Our simulations show that initial mass segregation is not sufficient to allow runaway merging of stars to occur in clusters with central densities typical for star clusters in the Milky Way.Comment: 25 pages, 9 figures, 3 tables, accepted for publication in Ap

The partnership: Space shuttle, space science, and space station

An overview of the NASA Space Station Program functions, design, and planned implementation is presented. The discussed functions for the permanently manned space facility include: (1) development of new technologies and related commercial products; (2) observations of the Earth and the universe; (3) provision of service facilities for resupply, maintenance, upgrade and repair of payloads and spacecraft; (4) provision of a transportation node for stationing, processing and dispatching payloads and vehicles; (5) provision of manufacturing and assembly facilities; (6) provision of a storage depot for parts and payloads; and (7) provision of a staging base for future space endeavors. The fundamental concept for the Space Station, as given, is that it be designed, operated, and evolved in response to a broad variety of scientific, technological, and commercial user interests. The Space Shuttle's role as the principal transportation system for the construction and maintenance of the Space Station and the servicing and support of the station crew is also discussed

Internationalization of New Product Development:Results from a Multiple Case Study on companies with Innovation Processes in Germany and India

A rich body of literature has emerged from research on Western new product development (NPD). However, the impact of country- and culture-specific influences on these processes has not been examined in detail yet. Hence, this study identifies the differences in NPD practices between the Indian and German research and development (R&amp;D) subsidiaries of multinational companies (MNCs). Data have been generated by interviews with R&amp;D executives in both countries across multiple cases. The study samples strategic, organisational, and operational aspects and indicates differences in process coordination, reward systems, NPD creativity techniques, market orientation, and the average age of NPD teams. Other aspects, such as top management support, the use of structured NPD processes, and the use of heterogeneous NPD teams, show no substantial differences between the countries. Our findings suggest that, while some aspects are universally applicable across cultural frontiers, Western companies must understand India's different expectations regarding NPD and adjust their practices accordingly.</jats:p

Permalloy-based carbon nanotube spin-valve

In this Letter we demonstrate that Permalloy (Py), a widely used Ni/Fe alloy, forms contacts to carbon nanotubes (CNTs) that meet the requirements for the injection and detection of spin-polarized currents in carbon-based spintronic devices. We establish the material quality and magnetization properties of Py strips in the shape of suitable electrical contacts and find a sharp magnetization switching tunable by geometry in the anisotropic magnetoresistance (AMR) of a single strip at cryogenic temperatures. In addition, we show that Py contacts couple strongly to CNTs, comparable to Pd contacts, thereby forming CNT quantum dots at low temperatures. These results form the basis for a Py-based CNT spin-valve exhibiting very sharp resistance switchings in the tunneling magnetoresistance, which directly correspond to the magnetization reversals in the individual contacts observed in AMR experiments.Comment: 3 page

On Convergence of the Inexact Rayleigh Quotient Iteration with the Lanczos Method Used for Solving Linear Systems

For the Hermitian inexact Rayleigh quotient iteration (RQI), the author has established new local general convergence results, independent of iterative solvers for inner linear systems. The theory shows that the method locally converges quadratically under a new condition, called the uniform positiveness condition. In this paper we first consider the local convergence of the inexact RQI with the unpreconditioned Lanczos method for the linear systems. Some attractive properties are derived for the residuals, whose norms are $\xi_{k+1}$'s, of the linear systems obtained by the Lanczos method. Based on them and the new general convergence results, we make a refined analysis and establish new local convergence results. It is proved that the inexact RQI with Lanczos converges quadratically provided that $\xi_{k+1}\leq\xi$ with a constant $\xi\geq 1$. The method is guaranteed to converge linearly provided that $\xi_{k+1}$ is bounded by a small multiple of the reciprocal of the residual norm $\|r_k\|$ of the current approximate eigenpair. The results are fundamentally different from the existing convergence results that always require $\xi_{k+1}<1$, and they have a strong impact on effective implementations of the method. We extend the new theory to the inexact RQI with a tuned preconditioned Lanczos for the linear systems. Based on the new theory, we can design practical criteria to control $\xi_{k+1}$ to achieve quadratic convergence and implement the method more effectively than ever before. Numerical experiments confirm our theory.Comment: 20 pages, 8 figures. arXiv admin note: text overlap with arXiv:0906.223

In vivo analysis of staphylococcus aureus-infected mice reveals differential temporal and spatial expression patterns of fhuD2

Staphylococcus aureus is an opportunistic human pathogen and a major cause of invasive infections such as bacteremia, endocarditis, pneumonia and wound infections. FhuD2 is a staphylococcal lipoprotein involved in the uptake of iron-hydroxymate and is under the control of the iron uptake regulator Fur. The protein is part of an investigational multi-component vaccine formulation that has shown protective efficacy in several murine models of infection. Even though fhuD2 expression was shown to be upregulated in murine kidneys infected with S. aureus, it is unknown whether the bacterium undergoes increased iron deprivation during prolonged infection. Furthermore, different infection niches of S. aureus might provide different environments and iron availability resulting in different fhuD2 expression pattern within different host organs. To address these questions, we characterized the in vitro expression of the fhuD2 gene and confirmed Fur-dependent iron-regulation of its expression. We further investigated its expression in mice infected with a bioluminescent reporter strain of S. aureus expressing the luciferase operon under the control of the fhuD2 promoter. The emission of bioluminescence in different organs was followed over a seven-day time course, as well as quantitative real-time PCR analysis of the RNA transcribed from the endogenous fhuD2 gene. Using this approach, we could show that fhuD2 expression was induced during infection in all organs analyzed and that differences in expression were observed in the temporal expression profiles, and between infected organs. Our data suggest that S. aureus undergoes increased iron deprivation during progression of infection in diverse host organs and accordingly induces dedicated iron acquisition mechanisms. Since FhuD2 plays a central role in providing the pathogen with the required iron, further knowledge of the patterns of fhuD2 expression in vivo during infection is instrumental in better defining the role of this antigen in S. aureus pathogenesis and as a vaccine antigen

Dynamical Interactions and the Black Hole Merger Rate of the Universe

Binary black holes can form efficiently in dense young stellar clusters, such as the progenitors of globular clusters, via a combination of gravitational segregation and cluster evaporation. We use simple analytic arguments supported by detailed N-body simulations to determine how frequently black holes born in a single stellar cluster should form binaries, be ejected from the cluster, and merge through the emission of gravitational radiation. We then convolve this ``transfer function'' relating cluster formation to black hole mergers with (i) the distribution of observed cluster masses and (ii) the star formation history of the universe, assuming that a significant fraction gcl of star formation occurs in clusters and that a significant fraction gcand of clusters undergo this segregation and evaporation process. We predict future ground--based gravitational wave (GW) detectors could observe ~500 (gcl/0.5) (gcand/0.1) double black hole mergers per year, and the presently operating LIGO interferometer would have a chance (50%) at detecting a merger during its first full year of science data. More realistically, advanced LIGO and similar next-generation gravitational wave observatories provide unique opportunities to constrain otherwise inaccessible properties of clusters formed in the early universe.Comment: 4 pages, 2 figures. To appear in PRD Rapid Communication

Merger of Black Holes in the Galactic Center

We present the results of three body simulations focused on understanding the fates of intermediate mass black holes (IBH) that drift within the central 0.5 pc of the Galaxy. In particular, we modeled the interactions between pairs of $4000 {\rm M}_{\odot}$ black holes as they orbit a central blac k hole of mass $4 \times 10^6 {\rm M}_{\odot}$. The simulations performed assume a Schwarzschild geometry and account for Chandrasekhar dynamical friction as well as acceleration resulting from energy lost due to gravitational radiation. We found the branching ratio for one of the orbiting IBHs to merge with the CBH was 0.95 and is independent of the inner IBH's initial eccentricity as well as the rate of sinking. This, coupled with an infall rate of $\sim 10^7$ yrs for an IBH to drift into the Galactic center, results in an IBH-CBH merger every $\lesssim 11$ Myrs. Lastly we found that the IBH-IBH-CBH triple body system ``resets'' itself, in the sense that a system with an inner I BH with an initially circular orbit generally left behind an IBH with a large eccentricity, whereas a system in which the inner IBH had a high eccentricity ($e_0 \sim 0.9$) usually left a remnant with low eccentricity. Branching ratios for different outcomes are also similar in the two cases.Comment: Official paper to appear in November 2008 issue of Ap