Conic deformation of the subglottic mucosa and its impact on the aerodynamics of the airflow over the vocal folds

Objective: This study mapped the variation in tissue elasticity of the subglottic mucosa, applied that data to provide initial models of the likely deformation of the mucosa during the myoelastic cycle, and hypothesised as to the impact on the process of phonation. Study Design: 6 donor human larynges were dissected along the sagittal plane to expose the vocal folds and subglottic mucosa. A Linear Skin Rheometer was used to apply a controlled shear force, and the resultant displacement was measured. This data provided a measure of the stress/strain characteristics of the tissue at each anatomical point. A series of measurements were taken at 2mm interval inferior of the vocal folds, and the change in elasticity determined. Results: It was found that the elasticity of the mucosa in the subglottic region increased linearly with distance from the vocal folds in all 12 samples. A simple deformation model indicated that under low pressure conditions the subglottic mucosa will deform to form a cone, which could result in a higher velocity thus amplifying the low pressure effect resulting from the Venturi principle, and could assist in maintaining laminar flow. Conclusions: This study indicated that the deformation of the subglottic mucosa could play a significant role in the delivery of a low pressure air flow over the vocal folds

Effect of Cavity Vacuum Pressure Diminution on Thermal Performance of Triple Vacuum Glazing

Long-term durability of the vacuum edge-seal plays a significant part in retrofitting triple vacuum glazing (TVG) to existing buildings in achieving towards zero-energy buildings (ZEB) target. Vacuum pressure decrement with respect to time between panes affect the thermal efficiency of TVG. This study reports a 3D finite element model, with validated mathematical methods and comparison, for the assessment of the influence of vacuum pressure diminution on the thermal transmittance (U value) of TVG. The centre-of-pane and total U values of TVG calculated to be 0.28 Wm−2K−1 and 0.94 Wm−2K−1 at the cavity vacuum pressure of 0.001 Pa. The results suggests that a rise in cavity pressure from 0.001 Pa to 100 kPa increases the centre-of-pane and total U values from 0.28 Wm−2K−1 and 0.94 Wm−2K−1 to 2.4 Wm−2K−1 and 2.58 Wm−2K−1, respectively. The temperature descent on the surfaces of TVG between hot and cold sides’ increases by decreasing the cavity vacuum pressure from 50 kPa to 0.001 Pa. To maintain the cavity vacuum pressure of 0.001 Pa for over 20 years of life span in the cavity of 10 mm wide edge sealed triple vacuum glazing, non-evaporable getters will maintain the cavity vacuum pressure that will enable the long-term durability to TVG

A new low-temperature hermetic composite edge seal for the fabrication of triple vacuum glazing

High performance low-cost vacuum glazing is a key development in the move to more energy-efficient buildings. This study reports the results of experimental and theoretical investigations into the development of a new low-temperature (less than 200˚C) composite edge seal. A prototype triple vacuum glazing of dimensions 300 mm x 300 mm was fabricated with a measured vacuum pressure of 4.8x10-2 Pa achieved. A three-dimensional finite-element model for this prototype triple vacuum glazing with the composite edge seal was also developed. Centre-of-pane and total thermal transmittance values for this small prototype of the triple vacuum glazing were predicted to be 0.33 Wm-2K-1 and 1.05 Wm-2K-1, respectively. It was predicted using the developed model that the thermal performance could be improved by reducing the width of the composite edge seal and by the use of soft low-emissivity coatings on the glass surfaces. Detailed three-dimensional isothermal contour plots of the modelled triple vacuum glazing are presented

The impact of boron seed priming on seedling establishment, growth, and grain biofortification of mungbean (Vigna radiata L.) in yermosols

Boron-deficiency in Yermosols is among the major constraints to mungbean productivity and grain biofortification in Pakistan. However, agronomic strategies such as boron (B) seed priming have potential to improve mungbean yield and grain biofortification. Moreover, deficiency to toxicity range for B is very narrow; therefore, it is pre-requisite to optimize its dose before field evaluation. A wire house experiment was planned out to reconnoiter the impact of seed priming with B on growth and quality of two cultivars of mungbean, i.e., ‘NM-2011’ and ‘NM-2016’. Four different B levels were used as seed priming, i.e., 0.01%, 0.05%, 0.1% and 1.0% B, (borax Na2B4O7.10H2O, 11.5% B) were tested, whereas hydropriming was regarded as control. Seed priming with 0.01% B significantly (p≤0.05) lowered time taken to start germination and time to reach 50% emergence, whereas improved mean emergence time, emergence index, final emergence percentage, number of leaves, dry and fresh weight of root, shoot, and total weight, root length, plant height, chlorophyll contents, number of pods and 100-grain weight, seeds per plant, grain yield per plant, B concentrations in stem and grain, grain protein, carbohydrate and fiber in both cultivars. Boron seed priming proved beneficial under a specific range; however, deficiency (hydropriming) and excess (above 0.01% B) of B were detrimental for mungbean growth and productivity. The cultivar ‘NM-2016’ had significantly (p≤0.05) higher yield due to prominent increase in yield related traits with 0.01% B priming as compared to ‘NM-2011’. In conclusion, B seed priming (0.01% B) seemed a feasible choice for improving mungbean growth, yield related traits and grain-B concentration of mungbean on Yermosols

Effects of oxidation on fatigue crack initiation and propagation in an advanced disc alloy

Powder metallurgy Ni-based superalloys are widely used for aeroengine turbine disc application due to their exceptional strength properties at elevated temperatures, good fatigue and creep performance as well as excellent corrosion and oxidation resistance. However, oxygen enhanced fatigue crack initiation and intergranular propagation at elevated temperatures in air is commonly observed in aeroengine turbine disc superalloys under dwell fatigue testing conditions [1-7], and this phenomenon is usually ascribed to either decohesion/reduction in cohesion strength of grain boundary (GB) due to dynamic embrittlement [8, 9] or GB oxide cracking caused by stress assisted grain boundary oxidation (SAGBO) [5, 10-12]. Although the influence of oxygen on fatigue crack initiation and propagation has been intensively studied, the underlying mechanism for the oxygen-assisted fatigue failure process is still not clear due to the complex composition of disc alloy and the interaction between environmental attack and mechanical load. In this study, fatigue tests were conducted on the Low Solvus, High Refractory (LSHR) alloy designed by NASA for turbine disc application, with a particular focus on studying the influence of the formation of GB oxides on fatigue crack initiation and propagation processes

High Fidelity Tape Transfer Printing Based On Chemically Induced Adhesive Strength Modulation

Transfer printing, a two-step process (i.e. picking up and printing) for heterogeneous integration, has been widely exploited for the fabrication of functional electronics system. To ensure a reliable process, strong adhesion for picking up and weak or no adhesion for printing are required. However, it is challenging to meet the requirements of switchable stamp adhesion. Here we introduce a simple, high fidelity process, namely tape transfer printing(TTP), enabled by chemically induced dramatic modulation in tape adhesive strength. We describe the working mechanism of the adhesion modulation that governs this process and demonstrate the method by high fidelity tape transfer printing several types of materials and devices, including Si pellets arrays, photodetector arrays, and electromyography (EMG) sensors, from their preparation substrates to various alien substrates. High fidelity tape transfer printing of components onto curvilinear surfaces is also illustrated

Bottle house: A case study of transdisciplinary research for tackling global challenges

This work was done in collaboration with colleagues from the institute of Engineering sciences and Architecture Research Institute The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Globalisation has brought a number of challenges to the fore, particularly those problems which require collaboration, innovation and capability development between nations. There are some complex issues piquing the attention of researchers with respect to sustainable development, such as, waste management, climate change, and access to amenities, housing or education. Non-Governmental Organisations, Institutions, governments and others working in the field of international development have been grappling with these difficulties for decades. However, it is becoming apparent that many of these difficulties require multifaceted solutions, particularly in Low and Middle Income countries (LMIC) where it is difficult to consolidate gains and fund schemes. Development work can sometimes be disjointed and inefficient, impairing the capability of local communities and inhibiting sustainable and innovative approaches. Transdisciplinary collaboration is reliably a more efficient way of tackling some of the most pertinacious challenges. This paper presents findings from a transdisciplinary research project focussed on developing resources and capacity for the construction of affordable homes in a low income community in Nigeria. The project explored the suitability of using upcycled materials such as plastic bottles and agricultural waste in construction. Using a user-centred, co-creation methodology, a team of experts from the UK and Nigeria worked with local entrepreneurs to build a prototype home. The study explores the functionality of the home and the sustainability of project. The findings demonstrate the benefits of tackling global challenges from a transdisciplinary perspective. This has implications for researchers focused on developing technical solutions for low-income communities

Computational modelling of full interaction between crystal plasticity and oxygen diffusion at a crack tip

Oxidation-promoted crack growth, one of the major concerns for nickel-based superalloys, is closely linked to the diffusion of oxygen into the crack tip. The phenomenon is still not well understood yet, especially the full interaction between oxygen diffusion and severe near-tip mechanical deformation. This work aimed at the development of a robust numerical strategy to model the full coupling of crystal plasticity and oxygen diffusion in a single crystal nickel-based superalloy. In order to accomplish this, finite element package ABAQUS is used as a platform to develop a series of user-defined subroutines to model the fully coupled process of deformation and diffusion. The formulation allowed easy incorporation of nonlinear material behaviour, various loading conditions and arbitrary model geometries. Using this method, finite element analyses of oxygen diffusion, coupled with crystal plastic deformation, were carried out to simulate oxygen penetration at a crack tip and associated change of near-tip stress field, which has significance in understanding crack growth acceleration in oxidation environment. Based on fully coupled diffusion-deformation analyses, a case study was carried out to predict crack growth rate in oxidation environment and under dwell-fatigue loading conditions, for which a two-parameter failure criterion, in terms of accumulated inelastic strain and oxygen concentration at the crack tip, has been utilized

Low cycle fatigue of a directionally solidified nickel-based superalloy: Testing, characterisation and modelling

Low cycle fatigue (LCF) of a low-carbon (LC) directionally-solidified (DS) nickel-base superalloy, CM247 LC DS, was investigated using both experimental and computational methods. Strain-controlled LCF tests were conducted at 850°C, with a loading direction either parallel or perpendicular to the solidification direction. Trapezoidal loading-waveforms with 2 s and 200 s dwell times imposed at the minimum and the maximum strains were adopted for the testing. A constant strain range of 2% was maintained throughout the fully-reversed loading conditions (strain ratio R = −1). The observed fatigue life was shorter when the loading direction was perpendicular to the solidification one, indicating an anisotropic material response. It was found that the stress amplitude remained almost constant until final fracture, suggesting limited cyclic hardening/softening. Also, stress relaxation was clearly observed during the dwell period. Scanning Electron Microscopy fractographic analyses showed evidence of similar failure modes in all the specimens. To understand deformation at grain level, crystal plasticity finite element modelling was carried out based on grain textures measured with EBSD. The model simulated the full history of cyclic stress-strain responses. It was particularly revealed that the misorientations between columnar grains resulted in heterogeneous deformation and localised stress concentrations, which became more severe when the loading direction was normal to a solidification direction, explaining the shorter fatigue life observed