Comparative Analysis of Sliding Resistance of Different Lingual Systems

Objective: To analyse and compare the frictional properties of 4 lingual systems combined with two types of stainless steel archwire (0.016x0.022, 0.018x0.025) and a 0.018x0.025 TMA archwire by simulating different misalignment situations in vitro. Material and Methods: Five randomly chosen brackets from each system (e-Brace, Harmony, Incognito, and STb) were used for the measurements and to simulate an upper first premolar extraction case. The friction tests were performed using a material testing machine in combination with a specialized test rig. Results: The lowest absolute friction values were found with the 0.016x0.022 SS wire in a passive configuration. STb provided the lowest mean friction, while Harmony brackets displayed the highest friction. The TMA Beta Titanium wire showed the highest friction values, but maintained proportions similar to those of the other wires as tip and torsion increased. Conclusion: The type of bracket has a significant impact on friction, and there is a positive correlation between mesiodistal bracket width and resistance to sliding. The archwire sections and materials and the vertical displacement, also significantly affect the friction generated by the system

Survival rate of indirectly bonded brackets using single vs. two-component orthodontic adhesive: A 12-month split-mouth clinical trial

Objective: Compare the bonding survival rate of two distinct bonding materials: Ortho Solo + Gradia LoFlo Resin and single component GC Ortho Connect. Materials and Methods: Indirect bonding fixed appliance treatment was required for 26 consecutive patients, 8 males and 18 females, with a mean age of 22.1 +/- 4.2 years. All patients were treated with SWM (Straight-Wire Mirabella) technique (Sweden and Martina, Due Carrare, Padova, Italy). Each patient's bonding process followed a contralateral pattern. Firstly, a 37 % orthophosphoric acid etching gel was used for 20 s, subsequently the single or two components light-cured adhesives were applied through a split-mouth cross-arch procedure. The patients underwent a 12-month follow-up period and brackets failures were rebounded, but not further included in the study. Statistical analysis was performed to analyse the survival rate of the bonding materials and the influence of the variables, with a significant level of α = 0,05. Results: The GC Connect group was used on 349 teeth, while the Ortho Solo + Gradia group was used on 351 teeth, and the indirect debonding rate was respectively 17.5% and 12.8%. With respect to the total sample, statistically significant values were found for both sex and dental arch. The bracket's survival rate for incisors, canines, premolars and molars was not significant. However, a higher debonding rate was clinically appreciable in upper and lower molars. Conclusion: In a 12-months observation period, considering all maxillary and mandibular teeth the indirect survival rate for the group GC Ortho Connect and Ortho Solo + Gradia was respectively 82.5% and 87.2%. Although the difference was not significant, a pronounced tendency to debonding for the single component group was appreciable from a clinically point of view

Measuring the accuracy of software vulnerability assessments: experiments with students and professionals

Assessing the risks of software vulnerabilities is a key process of software development and security management. This assessment requires to consider multiple factors (technical features, operational environment, involved assets, status of the vulnerability lifecycle, etc.) and may depend from the assessor's knowledge and skills. In this work, we tackle with an important part of this problem by measuring the accuracy of technical vulnerability assessments by assessors with dierent level and type of knowledge. We report an experiment to compare how accurately students with dierent technical education and security professionals are able to assess the severity of software vulnerabilities with the Common Vulnerability Scoring System (v3) industry methodology. Our results could be useful for increasing awareness about the intrinsic subtleties of vulnerability risk assessment and possibly better compliance with regulations. With respect to academic education, professional training and human resources selections our work suggests that measuring the effects of knowledge and expertise on the accuracy of software security assessments is feasible albeit not easy

Inverted Oscillator

The inverted harmonic oscillator problem is investigated quantum mechanically. The exact wave function for the confined inverted oscillator is obtained and it is shown that the associated energy eigenvalues are discrete and it is given as a linear function of the quantum number $n$.Comment: 4 page

Palatal skeletal anchorage: multiple applications with a single appliance

Using a single bone-borne maxillary appliance with twofold mechanics, that is, rapid palatal expander and nonfrictional distalizing appliance (Pendulum) is a valuable option to treat young-adult patients with poor compliance. In this particular case, the same appliance was used to disinclude 2.3, eliminating reaction forces on the arch. Therefore, the first expansive phase was followed by the distalizing phase. After enough space was obtained for the recovery of tooth 2.3, a triple-looped titanium-molybdenum alloy (TMA) spring was used to perform canine orthodontic traction. The core concept is that digital planning and optimal positioning of two palatal mini-screws can ensure a bicortical anchorage which, in turn, enabled to tolerate the different orthodontic phases. As a matter of fact, a tooth-bone-borne anchorage was followed by a pure bone-borne anchorage with no lost of stability

Correlation between mesio-distal teeth diameters and arch width

Objective: To verify the existence of a correlation between the mesio-distal size of teeth and the arch width by analyzing the data separately for maxillary and mandibular arch in patients with ideal occlusion. Material and Methods: 58 patients with ideal occlusion were studied, for a total of 276 files analyzed. Dental casts were then scanned using a professional scanner (Epson Perfection v 330) and images were obtained in TIFF format at 600 dpi. All single teeth measurements were carried out for all teeth of both arches using the VAM software (Vectra, Canfield Scientific, Fairfield, NJ, USA). The repeatability and reproducibility of the measurement method were evaluated using the Gauge R&R method. In case a correlation between tooth size and arch size is found to be significant, a linear regression analysis can be applied through the following statistical relationship: y=a+b*x, where y is the result (inter-molar distance “AvgB66” or inter-canine distance “Cusp 33”), and x the specific tooth. The a and b respectively represent the intercept (point of intersection between the line and the y axis) and the slope of the line that describes the regression ratio. Results: The statistical analysis highlights a significant correlation (p<1%) between the results of the mesio-distal measurements of each tooth and the two variables considered to define the size of each arch (“AvgB66” and “Cusp 33”). Based on these results, a numerical relationship "y=a+b*x" has been extrapolated. Thus, it is possible to calculate the estimated inter-molar or inter canine distance necessary to have the teeth aligned. Conclusion: The inter-canine and inter-molar distances can be estimated starting from measuring the mesio-distal diameter of a single tooth

Chromatin organisation and computer aided karyotyping of Triticum durum Desf. cv. Timilia

Abstract The tribe Triticeae includes three cereal genera Secale, Hordeum and Triticum and because of their economical and agronomical importance, the relationships among species on the tribe have been extensively investigated. The wild wheat relatives are an important source of genetic variation for cultivated species and wheat is an important crop of the mediterranean region. Banding pattern of metaphase chromosomes and nuclear DNA content in root meristematic cells of an old sicilian landrace "Timilia" were determined. Microdensitometric evaluation of nuclear absorption at different thresholds of optical density indicates the organization of chromatin in the interphase nuclei. Chromosome morphometric data, karyotype simmetry, the TF% values and Syi indices were determined. The results are compared with the data of other durum wheat varieties as Capeiti and Simeto

Randomised clinical trial: alosetron improves quality of life and reduces restriction of daily activities in women with severe diarrhoea-predominant IBS

Background: Patients with irritable bowel syndrome with diarrhoea (IBS-D) experience restriction in daily activities and decreased health-related quality of life (QOL). Aim To investigate effects of alosetron on patient-reported health-related QOL, satisfaction and productivity in women with severe IBS-D. Methods: A total of 705 women (severe IBS-D, Rome II criteria) randomised to alosetron 0.5 mg QD, 1 mg QD, 1 mg BID, or placebo for 12 weeks were studied. IBSQOL, treatment satisfaction, daily activities, and lost workplace productivity (LWP) were evaluated at randomisation and Week 12. Results: One or more doses of alosetron significantly improved all IBSQOL domains except for sexual function from baseline vs. placebo. The magnitude of IBSQOL changes was consistent with a clinically meaningful effect. Alosetron 0.5 mg QD and 1 mg BID significantly reduced IBS interference with social/leisure activities and LWP from baseline vs. placebo [social/leisure (mean ±S.E.) days lost: −6.7 ± 0.8, −7.0 ± 0.9, P < 0.01; LWP (mean ± S.E.) h lost: −11.0 ± 3.3, −21.1 ± 4.1, P < 0.05 respectively]. Significantly more patients treated with alosetron reported satisfaction vs. placebo. Improvements in IBSQOL, LWP, and treatment satisfaction significantly correlated with global improvement of IBS symptoms. The incidence of adverse events with alosetron was low with constipation being the most commonly reported event. A single case of ischaemic colitis occurred, in a patient receiving alosetron 0.5 mg QD. Conclusions: In women with severe IBS-D, alosetron treatment, including 0.5 mg QD, resulted in statistically significant and clinically relevant improvements in health-related QOL, restriction of daily activities and treatment satisfaction over placebo. IBS symptom improvement corresponded with positive changes in IBSQOL, LWP and treatment satisfaction

Higher Derivative Extension of 6D Chiral Gauged Supergravity

Six-dimensional (1,0) supersymmetric gauged Einstein-Maxwell supergravity is extended by the inclusion of a supersymmetric Riemann tensor squared invariant. Both the original model as well as the Riemann tensor squared invariant are formulated off-shell and consequently the total action is off-shell invariant without modification of the supersymmetry transformation rules. In this formulation, superconformal techniques, in which the dilaton Weyl multiplet plays a crucial role, are used. It is found that the gauging of the U(1) R-symmetry in the presence of the higher-order derivative terms does not modify the positive exponential in the dilaton potential. Moreover, the supersymmetric Minkowski(4) x S^2 compactification of the original model, without the higher-order derivatives, is remarkably left intact. It is shown that the model also admits non-supersymmetric vacuum solutions that are direct product spaces involving de Sitter spacetimes and negative curvature internal spaces.Comment: 32 pages; typos corrected, footnote in conclusions section adde