5,704 research outputs found
Formation of Hydrogenated Graphene Nanoripples by Strain Engineering and Directed Surface Self-assembly
We propose a new class of semiconducting graphene-based nanostructures:
hydrogenated graphene nanoripples (HGNRs), based on continuum-mechanics
analysis and first principles calculations. They are formed via a two-step
combinatorial approach: first by strain engineered pattern formation of
graphene nanoripples, followed by a curvature-directed self-assembly of H
adsorption. It offers a high level of control of the structure and morphology
of the HGNRs, and hence their band gaps which share common features with
graphene nanoribbons. A cycle of H adsorption/desorption at/from the same
surface locations completes a reversible metal-semiconductor-metal transition
with the same band gap.Comment: 11 pages, 5 figure
Collisionless galaxy simulations
Three-dimensional fully self-consistent computer models were used to determine the evolution of galaxies consisting of 100 000 simulation stars. Comparison of two-dimensional simulations with three-dimensional simulations showed only a very slight stabilizing effect due to the additional degree of freedom. The addition of a fully self-consistent, nonrotating, exponential core/halo component resulted in considerable stabilization. A second series of computer experiments was performed to determine the collapse and relaxation of initially spherical, uniform density and uniform velocity dispersion stellar systems. The evolution of the system was followed for various amounts of angular momentum in solid body rotation. For initally low values of the angular momentum satisfying the Ostriker-Peebles stability criterion, the systems quickly relax to an axisymmetric shape and resemble elliptical galaxies in appearance. For larger values of the initial angular momentum bars develop and the systems undergo a much more drastic evolution
Quantum Manifestation of Elastic Constants in Nanostructures
Generally, there are two distinct effects in modifying the properties of
low-dimensional nanostructures: surface effect (SS) due to increased
surface-volume ratio and quantum size effect (QSE) due to quantum confinement
in reduced dimension. The SS has been widely shown to affect the elastic
constants and mechanical properties of nanostructures. Here, using Pb nanofilm
and graphene nanoribbon as model systems, we demonstrate the QSE on the elastic
constants of nanostructures by first-principles calculations. We show that
generally QSE is dominant in affecting the elastic constants of metallic
nanostructures while SS is more pronounced in semiconductor and insulator
nanostructures. Our findings have broad implications in quantum aspects of
nanomechanics
Biochemistry and physiology of zebrafish photoreceptors
All vertebrates share a canonical retina with light-sensitive photoreceptors in the outer retina. These photoreceptors are of two kinds: rods and cones, adapted to low and bright light conditions, respectively. They both show a peculiar morphology, with long outer segments, comprised of ordered stacks of disc-shaped membranes. These discs host numerous proteins, many of which contribute to the visual transduction cascade. This pathway converts the light stimulus into a biological signal, ultimately modulating synaptic transmission. Recently, the zebrafish (Danio rerio) has gained popularity for studying the function of vertebrate photoreceptors. In this review, we introduce this model system and its contribution to our understanding of photoreception with a focus on the cone visual transduction cascade
Detection of Zebrafish Retinal Proteins by Infrared Western Blotting
The zebrafish retina is a canonical vertebrate retina. Since the past few years, with the continually growing genetic toolbox and imaging techniques, zebrafish plays a crucial role in retinal research. This protocol describes a method to quantitatively evaluate the expression of Arrestin3a (Arr3a) and G-protein receptor kinase7a (Grk7a) in the adult zebrafish retina at protein levels by infrared fluorescence western blot. Our protocol can be easily adapted to measure protein levels in additional zebrafish tissues
The origin recognition core complex regulates dendrite and spine development in postmitotic neurons
The origin recognition complex (ORC) ensures exactly one round of genome replication per cell cycle through acting as a molecular switch that precisely controls the assembly, firing, and inactivation of the replication initiation machinery. Recent data indicate that it may also coordinate the processes of mitosis and cytokinesis and ensure the proper distribution of replicated genome to daughter cells. We have found that the ORC core subunits are highly expressed in the nervous system. They are selectively localized to the neuronal somatodendritic compartment and enriched in the membrane fraction. siRNA knockdown of ORC subunits dramatically reduced dendritic branch formation and severely impeded dendritic spine emergence. Expression of ORC ATPase motif mutants enhanced the branching of dendritic arbors. The ORC core complex thus appears to have a novel role in regulating dendrite and dendritic spine development in postmitotic neurons
Persistent Current in the Ferromagnetic Kondo Lattice Model
In this paper, we study the zero temperature persistent current in a
ferromagnetic Kondo lattice model in the strong coupling limit. In this model,
there are spontaneous spin textures at some values of the external magnetic
flux. These spin textures contribute a geometric flux, which can induce an
additional spontaneous persistent current. Since this spin texture changes with
the external magnetic flux, we find that there is an anomalous persistent
current in some region of magnetic flux: near Phi/Phi_0=0 for an even number of
electrons and Phi/Phi_0=1/2 for an odd number of electrons.Comment: 6 RevTeX pages, 10 figures include
Scaffolding protein CcmM directs multiprotein phase separation in beta-carboxysome biogenesis
Biochemical, biophysical and structural analysis reveals how the scaffolding protein CcmM recruits the enzymes Rubisco and carbonic anhydrase into a condensate for encapsulation into carboxysomes-microcompartments in cyanobacteria that serve to optimize CO2 assimilation. Carboxysomes in cyanobacteria enclose the enzymes Rubisco and carbonic anhydrase to optimize photosynthetic carbon fixation. Understanding carboxysome assembly has implications in agricultural biotechnology. Here we analyzed the role of the scaffolding protein CcmM of the beta-cyanobacterium Synechococcus elongatus PCC 7942 in sequestrating the hexadecameric Rubisco and the tetrameric carbonic anhydrase, CcaA. We find that the trimeric CcmM, consisting of gamma CAL oligomerization domains and linked small subunit-like (SSUL) modules, plays a central role in mediation of pre-carboxysome condensate formation through multivalent, cooperative interactions. The gamma CAL domains interact with the C-terminal tails of the CcaA subunits and additionally mediate a head-to-head association of CcmM trimers. Interestingly, SSUL modules, besides their known function in recruiting Rubisco, also participate in intermolecular interactions with the gamma CAL domains, providing further valency for network formation. Our findings reveal the mechanism by which CcmM functions as a central organizer of the pre-carboxysome multiprotein matrix, concentrating the core components Rubisco and CcaA before beta-carboxysome shell formation
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