1,958 research outputs found

    Radiation data definitions and compilation for equipment qualification data bank

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    Dose definitions, physical properties, mechanical properties, electrical properties, and particle definitions are listed for insulators and dielectrics, elastomeric seals and gaskets, lubricants, adhesives, and coatings

    Surface Flaw Detection with Ferromagnetic Resonance Probes

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    Eddy current methods of flaw detection have been in use for many years. Frequencies used in this type of flaw detector normally range from tens of kilohertz to a few megahertz. We report on recent progress using a resonant probe which operates in the gigahertz frequency range, and compare its performance with classical eddy current methods

    Adaptive structures for whole-life energy savings

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    The design methodology described in this paper takes a substantial shift from conventional methods. Traditionally sizing is based on the worst expected load scenario. By contrast to this conventional passive approach the method presented here replaces passive member strategically with active elements (actuators) which are only activated when the loads reach a certain threshold. The structure can withstand low level of loads passively. Above the threshold, actuation comes in to allow the structure to cope with high but rare loading scenarios. Active control introduces operational energy consumption in addition to the energy embodied in a passive design. In this paper we use this dual design to minimize the overall energy required by the structures. This methodology has been used on a simple truss structure and it was showed that it allows significant weight saving compared to conventional passive design. We extend the application of the methodology to a more complex 3D structure. It is confirmed that an optimum activation threshold exists that leads to design that minimises the total energy of the structure. Compared to an optimised passive design we show that the total energy saving is 10-fold

    NYS Supreme Court Justice, F. Dana Winslow NYS Supreme Court Justice Testimony be fore the House Judiciary Committee on Causes and Effects of the Foreclosure Crisis

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    NYS Supreme Court Justice Winslow Testimony to Judiciary Before the House of Representatives

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    1863-06-23 B.F. Winslow, Claims Agent, requests proof of service for Ezra W. Leland

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    https://digitalmaine.com/cw_me_3rd_regiment_corr/1467/thumbnail.jp

    Increasing Historically Underserved and Underrepresented Student Completion in STEM Pathways at a Hispanic-Serving Institution: An Action Research Study

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    There is a demand for accountability for higher education institutions to increase student completion, specifically for institutions that enroll many students from historically underserved and underrepresented populations (HUUP). Meanwhile, labor market analysis presents a demand for skilled and diverse workers in science, technology, engineering, and mathematics (STEM) fields. Hispanic-serving institutions (HSI) have an advantage when supporting student completion to meet this workforce demand. This inquiry employed participatory action research (PAR) through a partnership with an HSI in rural Washington State. Using transformative worldview as the theoretical framework, this study aimed to determine the influence of completion planning for STEM students who represent HUUP. Research participants were students in the institution’s mathematics, engineering, science achievement (MESA) program. Two research questions guided this study and centered on how Hispanic participants and their lived experiences may inform completion planning for students from HUUP. The researchers sought to understand to what extent the MESA program’s support services impact student participation at a rural institution. This study collected nonquantitative data through a two-phase approach consisting of a survey and focus groups. The data analysis determined two key themes related to the study’s research questions: student barriers to completion at entry and strategies to support completion. The study’s findings led to four program-specific recommendations and three implications for policy-making decisions for the community partner’s leadership and for other higher education leaders seeking to increase student completion for students from HUUP into STEM pathways

    Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients

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    Exosomes are cellular secretory vesicles containing microRNAs (miRNAs). Once secreted, exosomes are able to attach to recipient cells and release miRNAs potentially modulating the function of the recipient cell. We hypothesized that exosomal miRNA expression in brains of patients diagnosed with schizophrenia (SZ) and bipolar disorder (BD) might differ from controls, reflecting either disease-specific or common aberrations in SZ and BD patients. The sources of the analyzed samples included McLean 66 Cohort Collection (Harvard Brain Tissue Resource Center), BrainNet Europe II (BNE, a consortium of 18 brain banks across Europe) and Boston Medical Center (BMC). Exosomal miRNAs from frozen postmortem prefrontal cortices with well-preserved RNA were isolated and submitted to profiling by Luminex FLEXMAP 3D microfluidic device. Multiple statistical analyses of microarray data suggested that certain exosomal miRNAs were differentially expressed in SZ and BD subjects in comparison to controls. RT-PCR validation confirmed that two miRNAs, miR-497 in SZ samples and miR-29c in BD samples, have significantly increased expression when compared to control samples. These results warrant future studies to evaluate the potential of exosome-derived miRNAs to serve as biomarkers of SZ and BD
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