Direct mass measurements of 19B, 22C, 29F, 31Ne, 34Na and other light exotic nuclei

We report on direct time-of-flight based mass measurements of 16 light neutron-rich nuclei. These include the first determination of the masses of the Borromean drip-line nuclei $^{19}$B, $^{22}$C and $^{29}$F as well as that of $^{34}$Na. In addition, the most precise determinations to date for $^{23}$N and $^{31}$Ne are reported. Coupled with recent interaction cross-section measurements, the present results support the occurrence of a two-neutron halo in $^{22}$C, with a dominant $\nu2s_{1/2}^2$ configuration, and a single-neutron halo in $^{31}$Ne with the valence neutron occupying predominantly the 2$p_{3/2}$ orbital. Despite a very low two-neutron separation energy the development of a halo in $^{19}$B is hindered by the 1$d_{5/2}^2$ character of the valence neutrons.Comment: 5 page

High precision position measurements at high counting rates with drift chambers and multi-hit electronics

11 pages, 7 figure

Chromosome Observation of Stephania cepharantha HAYATA

1.玉咲ツヅラフヂ(Stephania cepharantha HAYATA)の栽培に於いて, 雄株と雌株の比は栽培観察者の云う如く雌本が少いと云う事は無く, 大体1 : 1に分離す。2.雄株の減数分裂に於いてn=13なる事がたしかめられ形態的に見てXYなる性染色体の存在する事を認めた。3.雌雄両株の体細胞に於いて2n=26なる染色体が算えられた。雄株は24の常染色体とXYなる性染色体を持ち, 雌株は24の常染色体とXXなる性染色体を持つ事が認められた。 / The separating ratio of female and male plants of Stephania cepharantha HAYATA was almost equally expressed. The somatic chromosome numbers of them were both 26. The female plant had 24 autosom and XX chromosomes; in the other hand, the male had 24 autosom and XY chromosomes. At meiosis in P. M. Cs., the number of reduced chromosomes was found to be 13 at polar views in the heterotypic metaphase. One unequal pair of chromosomes was observed in polar and side views of the heterotypic metephase. One of its two members was about 1.5-2.0 larger than the other

Epidemiology of knee osteoarthritis in general practice: a registry-based study

OBJECTIVES: The present study investigated (1) trends in the prevalence and incidence of knee osteoarthritis over a 20-year period (1996-2015); (2) trends in multimorbidity and (3) trends in drug prescriptions. DESIGN: Registry-based study. SETTING: Primary healthcare, Flanders, Belgium. PARTICIPANTS: Data were collected from Intego, a general practice-based morbidity registration network. In the study period between 1996 and 2015, data from 440 140 unique patients were available. OUTCOME MEASURES: Trends in prevalence and incidence rate of knee osteoarthritis were computed using joinpoint regression analysis. The mean disease count was calculated to assess trends in multimorbidity. In addition, the number of drug prescriptions was identified by the Anatomical Therapeutic Chemical Classification code and trends were equally recorded with joinpoint regression. RESULTS: The total age-standardised prevalence of knee osteoarthritis increased from 2.0% in 1996 to 3.6% in 2015. An upward trend was observed with an average annual percentage change (AAPC) of 2.5 (95% CI 2.2 to 2.9). In 2015, the prevalence rates in the 10 year age groups from the 45-54 years age group onwards were 3.1%, 5.6%, 9.0% and 13.9%, to reach 15.0% in people aged 85 years and older. The incidence remained stable with 3.75 per thousand in 2015 (AAPC=-0.5, 95% CI -1.4 to 0.5). The mean disease count significantly increased from 1.63 to 2.34 (p<0.001) for incident cases with knee osteoarthritis. Finally, we observed a significantly positive trend in the overall prescription of acetaminophen (AAPC=6.7, 95% CI 5.6 to 7.7), weak opioids (AAPC=4.0, 95% CI 0.9 to 7.3) and glucosamine (AAPC=8.6, 95% CI 2.4 to 15.1). Oral non-steroidal anti-inflammatory drugs were most prescribed, with a prevalence rate of 29.8% in 2015, but remained stable during the study period (AAPC=0.0, 95% CI -1.1 to 1.1). CONCLUSIONS: Increased prevalence, multimorbidity, and number of drug prescriptions confirm an increased burden of knee osteoarthritis. In future, these trends can be used to prioritise initiatives for improvement in care

Educational outreach visits to improve knee osteoarthritis management in primary care

Contains fulltext : 201795.pdf (publisher's version ) (Open Access

Management of the diabetic patient in a resource-constrained environment

A century ago diabetes was virtually unknown in Africa. Currently 10 million people are living with this disease in Africa and the number is predicted to double by 2025. Type 2 diabetes accounts for 85 to 95% of all cases in the region. The main factors responsible for the rapid increase in the prevalence of diabetes in sub-Saharan Africa are an aging population, unhealthy diet, overweight and obesity, and a sedentary lifestyle, closely related to rapid urbanisation of the population in the region