Tanggapan Mahasiswa Ilmu Komunikasi Universitas Hasanuddin Terhadap Tayangan “Ini Talkshow” Di Net (News and Entertainment)

The aims of this study are to determine the responses of students of Hasanuddin University Communication Sciences toward the broadcast “IniTalkshow” in NET; and to know the factors that influence the responses of the students of Hasanuddin University Communication Sciences toward the broadcast “IniTalkshow” in NET.The research was conducted in Makassarfor approximately two months, namely from March to April 2016. The research populationswere taken from the students of Hasanuddin UniversityCommunication Sciences. The respondents were determined by proportionate stratified random sampling based on certain criteria. The technique of determining samples using Isaac and Michaeltables. The type of this researchuses quantitative methods with descriptive approach.The primary data was collected by using a questionnaire. The method of collecting data using a structured questionnaire and submitted to the respondent. The secondary data was done by observation, library research both taken from books and internet sites which are relevant to the focus of the problem. The data collected was then analyzed quantitatively by describing the data in the form of a frequency table. The research results showed that the response of students of HasanuddinUniversity Communication Sciences toward the broadcast “IniTalkshow” in NET were good. It was proved based on the number of responses obtained as many as 161 respondents. It was also founded that the purpose of the students of Hasanuddin University Communication Sciences to watch “IniTalkshow” was getting entertainment and leisure. Studi ini bertujuan untuk mengetahui tanggapan mahasiswa Ilmu Komunikasi Universitas Hasanuddin terhadap tayangan Ini Talkshow di NET. untuk mengetahui faktor-faktor yang mempengaruhi tanggapan mahasiswa Ilmu Komunikasi Universitas Hasanuddin terhadap tayangan Ini Talkshow di NET. Penelitian ini dilakukan selama kurang lebih dua bulan, yaitu Maret-April 2016 yang dilaksanakan di Kota Makassar. Adapun populasi penelitian ini adalah Mahasiswa Ilmu Komunikasi Universitas Hasanuddin. Responden penelitian ini ditentukan secara proportionate stratified random sampling berdasarkan kriteria-kriteria tertentu. Adapun teknik penentuan jumlah sampel menggunakan tabel Isaac dan Michael. Tipe penelitian ini menggunakan metode kuantitatif dengan pendekatan deskriptif Data primer dikumpulkan dengan menggunakan kusioner, cara pengumpulan data dengan menggunakan daftar pertanyaan yang berstruktur dan diajukan kepada responden. Data sekunder dilakukan dengan observasi, studi pustaka baik itu dari buku-buku, dan situs internet yang relevan dengan fokus permasalahan. Data yang berhasil dikumpulkan selanjutnya dianalisis secara kuantitaf dengan mendeskripsikan data dalam bentuk tabel frekuensi. Hasil penelitian menunjukkan bahwa tanggapan mahasiswa Ilmu Komunikasi Universitas Hasanuddin terhadap tayangan Ini Talkshow di NET dinilai bagus. Ini didasarkan dari jumlah tangapan yang diperoleh sebanyak 161 responden. Diketahui pula bahwa tujuan mahasiswa Ilmu Komunikasi Universitas Hasanuddin dari menonton Ini Talkshow adalah untuk mencari hiburan dan mengisi waktu luang

Variants at APOE influence risk of deep and lobar intracerebral hemorrhage

Objective Prior studies investigating the association between APOE alleles ε2/ε4 and risk of intracerebral hemorrhage (ICH) have been inconsistent and limited to small sample sizes, and did not account for confounding by population stratification or determine which genetic risk model was best applied. Methods We performed a large-scale genetic association study of 2189 ICH cases and 4041 controls from 7 cohorts, which were analyzed using additive models for ε2 and ε4. Results were subsequently meta-analyzed using a random effects model. A proportion of the individuals (322 cases, 357 controls) had available genome-wide data to adjust for population stratification. Results Alleles ε2 and ε4 were associated with lobar ICH at genome-wide significance levels (odds ratio [OR] = 1.82, 95% confidence interval [CI] = 1.50–2.23, p = 6.6 × 10 −10 ; and OR = 2.20, 95%CI = 1.85–2.63, p = 2.4 × 10 −11 , respectively). Restriction of analysis to definite/probable cerebral amyloid angiopathy ICH uncovered a stronger effect. Allele ε4 was also associated with increased risk for deep ICH (OR = 1.21, 95% CI = 1.08–1.36, p = 2.6 × 10 −4 ). Risk prediction evaluation identified the additive model as best for describing the effect of APOE genotypes. Interpretation APOE ε2 and ε4 are independent risk factors for lobar ICH, consistent with their known associations with amyloid biology. In addition, we present preliminary findings on a novel association between APOE ε4 and deep ICH. Finally, we demonstrate that an additive model for these APOE variants is superior to other forms of genetic risk modeling previously applied. ANN NEUROL 2010Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/78478/1/22134_ftp.pd

Independent susceptibility markers for atrial fibrillation on chromosome 4q25

Background-: Genetic variants on chromosome 4q25 are associated with atrial fibrillation (AF). We sought to determine whether there is more than 1 susceptibility signal at this locus. Methods and results-: Thirty-four haplotype-tagging single-nucleotide polymorphisms (SNPs) at the 4q25 locus were genotyped in 790 case and 1177 control subjects from Massachusetts General Hospital and tested for association with AF. We replicated SNPs associated with AF after adjustment for the most significantly associated SNP in 5066 case and 30 661 referent subjects from the German Competence Network for Atrial Fibrillation, Atherosclerosis Risk In Communities Study, Cleveland Clinic Lone AF Study, Cardiovascular Health Study, and Rotterdam Study. All subjects were of European ancestry. A multimarker risk score composed of SNPs that tagged distinct AF susceptibility signals was constructed and tested for association with AF, and all results were subjected to meta-analysis. The previously reported SNP, rs2200733, was most significantly associated with AF (minor allele odds ratio 1.80, 95% confidence interval 1.50 to 2.15, P=1.2×10) in the discovery sample. Adjustment for rs2200733 genotype revealed 2 additional susceptibility signals marked by rs17570669 and rs3853445. A graded risk of AF was observed with an increasing number of AF risk alleles at SNPs that tagged these 3 susceptibility signals. Conclusions-: We identified 2 novel AF susceptibility signals on chromosome 4q25. Consideration of multiple susceptibility signals at chromosome 4q25 identifies individuals with an increased risk of AF and may localize regulatory elements at the locus with biological relevance in the pathogenesis of AF

Determinants of weight, psychological status, food contemplation and lifestyle changes in patients with obesity during the COVID-19 lockdown: a nationwide survey using multiple correspondence analysis

Introduction The corona virus disease 2019 (COVID-19) pandemic forced most of the Italian population into lockdown from 11 March to 18 May 2020. A nationwide survey of Italian Clinical Nutrition and Dietetic Services (Obesity Centers or OCs) was carried out to assess the impact of lockdown restrictions on the physical and mental wellbeing of patients with obesity (PWO) who had follow-up appointments postponed due to lockdown restrictions and to compare determinants of weight gain before and after the pandemic. Methods We designed a structured 77-item questionnaire covering employment status, diet, physical activity and psychological aspects, that was disseminated through follow-up calls and online between 2 May and 25 June 2020. Data were analyzed by multiple correspondence analysis (MCA) and multiple linear regression. Results A total of 1,232 PWO from 26 OCs completed the questionnaires (72% female, mean age 50.2 +/- 14.2 years; mean BMI 34.7 +/- 7.6 kg/m(2); 41% obesity class II to III). During the lockdown, 48.8% gained, 27.1% lost, while the remainder (24.1%) maintained their weight. The mean weight change was +2.3 +/- 4.8 kg (in weight gainers: +4.0 +/- 2.4 kg; +4.2% +/- 5.4%). Approximately 37% of participants experienced increased emotional difficulties, mostly fear and dissatisfaction. Sixty-one percent reduced their physical activity (PA) and 55% experienced a change in sleep quality/quantity. The lack of online contact (37.5%) with the OC during lockdown strongly correlated with weight gain (p < 0.001). Using MCA, two main clusters were identified: those with unchanged or even improved lifestyles during lockdown (Cluster 1) and those with worse lifestyles during the same time (Cluster 2). The latter includes unemployed people experiencing depression, boredom, dissatisfaction and increased food contemplation and weight gain. Within Cluster 2, homemakers reported gaining weight and experiencing anger due to home confinement. Conclusions Among Italian PWO, work status, emotional dysregulation, and lack of online communication with OCs were determinants of weight gain during the lockdown period

Highlights lecture EANM 2015: the search for nuclear medicine’s superheroes

The EANM 2015 Annual Congress, held from October 10th to 14th in Hamburg, Germany, was outstanding in many respects. With 5550 participants, this was by far the largest European congress concerning nuclear medicine. More than 1750 scientific presentations were submitted, with more than 250 abstracts from young scientists, indicating that the future success of our discipline is fuelled by a high number of young individuals becoming involved in a multitude of scientific activities. Significant improvements have been made in molecular imaging of cancer, particularly in prostate cancer. PSMA-directed PET/CT appears to become a new gold standard for staging and restaging purposes. Novel tumour specific compounds have shown their potential for target identification also in other solid neoplasms and further our understanding of tumour biology and heterogeneity. In addition, a variety of nuclear imaging techniques guiding surgical interventions have been introduced. A particular focus of the congress was put on targeted, radionuclide based therapies. Novel theranostic concepts addressing also tumour entities with high incidence rates such as prostate cancer, melanoma, and lymphoma, have shown effective anti-tumour activity. Strategies have been presented to improve further already established therapeutic regimens such as somatostatin receptor based radio receptor therapy for treating advanced neuroendocrine tumours. Significant contributions were presented also in the neurosciences track. An increasing number of target structures of high interest in neurology and psychiatry are now available for PET and SPECT imaging, facilitating specific imaging of different subtypes of dementia and movement disorders as well as neuroinflammation. Major contributions in the cardiovascular track focused on further optimization of cardiac perfusion imaging by reducing radiation exposure, reducing scanning time, and improving motion correction. Besides coronary artery disease, many contributions focused on cardiac inflammation, cardiac sarcoidosis, and specific imaging of large vessel vasculitis. The physics and instrumentation track included many highlights such as novel, high resolution scanners. The most noteworthy news and developments of this meeting were summarized in the highlights lecture. Only 55 scientific contributions were mentioned, and hence they represent only a brief summary, which is outlined in this article. For a more detailed view, all presentations can be accessed by the online version of the European Journal of Nuclear Medicine and Molecular Imaging (Volume 42, Supplement 1)

Influenza dell\u2019invecchiamento in legno di ciliegio sulla componente antocianica e sul colore di vini rossi

L\u2019affinamento in legno \ue8 una pratica utilizzata in enologia al fine di migliorare le caratteristiche organolettiche dei vini. Tra gli altri, uno dei fenomeni che concorre a questa evoluzione \ue8 legato alla stabilizzazione della componente antocianica attraverso una serie di reazioni di addizione e condensazione tra i pigmenti stessi ed alcuni dei composti presenti nei vini. Sebbene tradizionalmente questo processo sia condotto utilizzando fusti di rovere (francese o americano), negli ultimi anni \ue8 progressivamente cresciuto l\u2019interesse verso l\u2019uso di essenze legnose alternative, di minor costo o pi\uf9 vicine a specifiche tradizioni enologiche regionali. Lo scopo della presente ricerca \ue8 stato quello di porre a confronto l\u2019evoluzione del colore e dei derivati antocianici in vini affinati in contenitori di rovere (225 L) e di ciliegio (225L e 1000L). I dati ottenuti dimostrano come le tesi affinate in ciliegio siano evolute in maniera pi\uf9 rapida, probabilmente a causa di una maggiore porosit\ue0 del legno. Nonostante un tenore finale in antocianine monomere pari a circa 1/3 rispetto alle prove affinate in rovere, le tesi conservate in barriques di ciliegio mostravano tonalit\ue0 ed intensit\ue0 coloranti non dissimili da quelle ottenute in legno di rovere, grazie alla maggior presenza di derivati antocianici e di polimeri colorati. Le tesi hanno evidenziato, inoltre, differenze significative nella evoluzione delle antocianine acilate. L\u2019uso di fusti di ciliegio da 1000L \ue8 apparso promuovere il miglior compromesso tra rapidit\ue0 dei fenomeni di stabilizzazione del colore ed adeguato mantenimento del patrimonio antocianico endogeno

PRE-FERMENTATIVE REPLACEMENT OF SULPHUR DIOXIDE BY LYSOZYME AND OENOLOGICAL TANNINS: EFFECT ON THE FORMATION AND EVOLUTION OF VOLATILE COMPOUNDS DURING THE BOTTLE STORAGE OF WHITE WINES

In this work, the effects on volatile profile of the pre-fermentative substitution of SO2 with lysozyme and oenological tannins were studied in white wines. At the same time, in order to understand the changes of volatile compounds in SO2-free wines, the evolution of volatiles was evaluated over one year of storage in bottles. For this purpose, a number of laboratory scale fermentations of Sauvignon Blanc musts were carried out and the effects of three variables (SO2, lysozyme and oenological tannins) were investigated by means of GC-MS analysis. Results showed that the replacement of SO2 with lysozyme and oenological tannins influenced the volatile composition of wines at the end of the alcoholic fermentation. Wines fermented with SO2 showed higher total alcohol amounts, while the presence of oenological tannins augmented the level of esters. The presence of SO2 influenced as well the alcohols and esters profiles of wines during bottle storage. Also, the presence of oenological tannins displayed a positive role in maintaining the amounts of esters over certain levels in wine stored for 1 year, likely due to their oxygen scavenging ability. By contrast, acids were less affected by the investigated adjuvants both at the end of the alcoholic fermentation and during the storage time

PETIT VERDOT,MEGLIO SE IN PUREZZA. L'INNOVAZIONE DI PRODOTTO NELLA SICILIA ENOLOGICA.

Il settore vitivinicolo siciliano negli ultimi anni ha subito profonde e radicali trasformazioni, risultato di nuove filosofie operative applicate alla gestione dei processi produttivi e funzionali alla produzione di una tipologia di vini di qualità con caratteristiche nutraceutiche e sensoriali di pregio, in linea con le richieste del consumatore moderno, alla ricerca di prodotti che rispondano a esigenze di qualità, igiene e sicurezza alimentare. In Sicilia, nel recente passato, la crescita culturale di una nuova fascia di giovani imprenditori sensibili alle innovazioni di processo e di prodotto ha reso possibile il trasferimento dei risultati della ricerca scientifica al processo produttivo e il successo riportato del Nero d''Avola, affermatosi nei canali di commercializzazione su scala mondiale quale prodotto innovativo diqualità, può essere considerato il riferimento principe di una politica di gestione produttiva vitivinicola moderna. Sul piano economico, i riflessi negativi che oggi interessano il settore vitivinicolo di Paesi storici produttori di vino, quali Italia e Francia, sembrano essere riconducibili alle nuove strategie di mercato dettate da una competizione globalizzata, che vede Paesi emergenti, come Stati Uniti, Cile, Argentina, Australia e Cina competere nel mercato internazionale con prezzi nettamente più convenienti rispetto a quelli italiani e francesi. Si rende necessario quindi dotare i prodotti siciliani di un sempre maggiore valore aggiunto, attraverso l''implementazione di idee e progetti finalizzati all''innovazione di processo e di prodotto, con particolare riferimento alla produzione di nuove tipologie di vini con caratteristiche nutraceutiche e sensoriali di eccellenza. In questa ottica si inserisce lo scopo di questo lavoro, finalizzato alla caratterizzazione, qualificazione e valorizzazione di vini rossi prodotti in Sicilia da uve nere della varietà Petit Verdot, un vitigno di origine bordolese comparso di recente nel panorama vitivinicolo siciliano