Evaluating GAIA performances on eclipsing binaries. III. Orbits and stellar parameters for UW LMi, V432 Aur and CN Lyn

The orbits and physical parameters of three detached F and G-type eclipsing binaries have been derived combining Hipparcos H(P) photometry with 8480-8740 Ang ground-based spectroscopy, simulating the photometric+spectroscopic observations that the GAIA mission will obtain. Tycho B(T) and V(T) light curves are too noisy to be modeled for the three targets, and only mean Tycho colors are retained to constrain the temperature. No previous combined photometric+spectroscopic solution exists in literature for any of the three targets. Quite remarkably, CN Lyn turned out to be an equal masses F5 triple system. Distances from the orbital solutions agree within the astrometric error with the Hipparcos parallaxes.Comment: A&A, accepted in pres

Development of Ultra-Fast Silicon Detectors for 4D-tracking

Ultra-Fast Silicon Detectors (UFSD) are thin silicon detectors, based on the Low-Gain Avalanche Diode (LGAD) technology, designed to perform 4Dtracking. The main features of UFSD are described, together with two different sets of measurement, which demonstrate that the innovative characteristics of these sensors allow achieving a time resolution of about 30 ps up to a fluence of φ = 1015 neq/cm2

Avaliação in vitro de genótipos de citros a Phytophthora parasitica.

Este trabalho teve como objetivo avaliar in vitro a reação de porta-enxertos de citros (Citrus spp.) a Phytophthora parasitica. As plântulas foram cultivadas em meio MS por 40 dias sendo, submetidas a fotoperíodo de 18 h, à temperatura de 25 ºC. A inoculação foi realizada através da inserção de agulha infestada com micélio de P. parasitica. A avaliação foi realizada aos 15 dias após a inoculação, medindo-se o comprimento das lesões em centímetros. O delineamento experimental foi inteiramente casualizado, com 15 repetições. Os resultados estão de acordo com as reações de campo dos genótipos e podem ser de grande utilidade em trabalhos envolvendo resistência varietal e seleção precoce de plantas

New Perspective in HCV Clinical and Economical Management of the Current and Future Therapies

Hepatitis C virus (HCV) is a progressive disease that infects more than 185 million individuals worldwide and is associated with persistence of viral replication and ongoing necroinflammation and fibrosis. To date 20% of patients chronically infected with HCV progress to cirrhosis. Epidemiological studies demonstrate that the incidence of HCV is not well known, because acute infection is generally asymptomatic. The global prevalence is about 2.2% and there is a large degree of geographic variability. Before the 2011, the gold standard of therapy for the treatment of chronic hepatitis C (CHC) was based on the combination of pegylated Interferon (peg-IFN) and Ribavirin (RBV). However, several aspects related to safety profile limited their use in clinical practice. In the recent years, thanks to basic research on HCV structure and replicative cycle, it has been possible to develop direct acting antiviral drugs that have dramatically increased the viral clearance rate. Specifically, the advent of the triple therapy employing direct acting antivirals has dramatically increased the viral clearance rate, from less than 10%, with the initial regimen of IFN monotherapy, to more than 95% with the current therapy. Even though new medications for hepatitis C are effective disease modifiers and have the potential, in a long term perspective, to eradicate the pathology, the cost of new treatments are unlikely to be sustainable for the NHSs. The evidence documenting the effectiveness and tolerability of the new therapies for HCV and several pharmacoeconomic analysis, shows that despite the cost, the new treatments can be considered cost-effective in the long period. However, the health care systems are unable to compensate the height financial resources immediately needed for treating patients with the long terms savings that will be obtained from the eradication of HCV. Indeed, new pharmaceutical policy and a global commitment is required to improve strategies of treatment and price negotiation with pharmaceutical companies to move from a theoretical cost-effectiveness approach to a practical cost-sustainable reality

An MCDA-based approach for creditworthiness assessment

Il working paper è inserito nell'archivio RePEc. http://ideas.repec.org/p/vnm/wpaper/177.htm

Caracterização de raízes e da qualidade da massa de genótipos de mandioca para consumo in natura no estado do Acre.

A cultura da mandioca apresenta expressiva importância social e econômica para o Estado do Acre. A cultura é tipicamente explorada por milhares de pequenos produtores sendo parte da produção usada na subsistência e outra como fonte de renda obtida com a venda principalmente da farinha

Ética e pessoa humana segundo o raciovitalismo hispânico: contribuições da filosofia de julián marías

Se trata de exponer y examinar los argumentos del filósofo Julián Marías en relación con el problema de la ética de la persona humana, desde la perspectiva de la vida humana y de la Antropología metafísica. Integrante de la “Escuela de Madrid”, su pensamiento ha sido inspirado por la filosofía raciovitalista de Ortega y Gasset. En este trabajo se pretende recuperar el contexto de esa influencia, para introducir los principales conceptos de su modelo teórico, y presentar sus consideraciones sobre la vida como un argumento biográfico proyectivo, la instalación de las circunstancias y las mundanidades como formas de hacer la persona

Evaluating GAIA performances on eclipsing binaries. II. Orbits and stellar parameters for V781 Tau, UV Leo and GK Dra

The orbits and physical parameters of three close, double-lined G0 eclipsing binaries have been derived combining H_P, V_T, B_T photometry from the Hipparcos/Tycho mission with 8480-8740 \AA ground-based spectroscopy. The setup is mimicking the photometric and spectroscopic observations that should be obtained by GAIA. The binaries considered here are all of G0 spectral type, but each with its own complications: V781 Tau is an overcontact system with components of unequal temperature, UV Leo shows occasional surface spots and GK Dra contains a delta-Scuti variable. Such peculiarities will be common among binaries to be discovered by GAIA. We find that the values of masses, radii and temperatures for such stars can be derived with a 1-2% accuracy using the adopted GAIA-like observing mode.Comment: accepted for publication in Astronomy and Astrophysics, contains 5 Tables and 3 Figures; correction of an important typ