Development of Acid-Sensitive Platinum(II) Complexes With Protein-Binding Properties

Four new protein-binding platinum(II) complexes, 10, 11, 21, 22, in which the dichloroplatinum moiety is coordinated either to a carbon-substituted or a nitrogen-substituted ethylene diamino ligand, were prepared in ten-step syntheses. According to pH-dependent stability studies with strictly related compounds, 11 and 22 exhibit acid-sensitive properties

Political Skill Moderates the Success of Psychopaths at the Workplace

On one hand, psychopaths tend to be callous, emotionally deficient, aggressive, self promoting, impulsive, and pursuant of unmitigated agency regardless of the extent to which it comes at the expense of others. On the other hand, by all accounts, psychopaths tend to be charming, seductive, self-confident, composed, risk-seeking, and adept at impression management (Babiak & Hare, 2006; Paulhus & Williams, 2002). Therefore, the purpose of this study was to reconcile these contrasting positions by examining whether (non-violent) psychopaths truly can be “successful” in the workplace. Drawing on socioanalytic theory (Hogan, 1983), we hypothesized that psychopaths in possession of political skill would be better able to package, conceal, and/or restrain their desires to get ahead in such a way as to be perceived as less counterproductive and more adaptive. Results provided support for these hypotheses. Implications for theory, practice, and future research are provided in light of a number of notable strengths and limitations

Conformation Dynamics

This article surveys the present state of the transfer operator approach to the effective dynamics of metastable dynamical systems and the variety of algorithms associated with it

Tracing Electron-Ion Recombination in Nanoplasmas Produced by Extreme- Ultraviolet Irradiation of Rare-Gas Clusters

We investigate electron-ion recombination in nanoplasmas produced by the ionization of rare-gas clusters with intense femtosecond extreme-ultraviolet (XUV) pulses. The relaxation dynamics following XUV irradiation is studied using time-delayed 790-nm pulses, revealing the generation of a large number of excited atoms resulting from electron-ion recombination. In medium-sized Ar-Xe clusters, these atoms are preferentially created in the Xe core within 10 ps after the cluster ionization. The ionization of excited atoms serves as a sensitive probe for monitoring the cluster expansion dynamics up to the ns time scale