11 research outputs found
In-hospital resource utilization in surgical and transcatheter aortic valve replacement
Lerneffekte bei der Einführung der kathetergestützten Aortenklappenimplantation (TAVI): deutsche Erfahrungen aus mehr als 32.000 Fällen
Prevalence and impact of critical limb ischaemia on in-hospital outcome in transcatheter aortic valve implantation in Germany
A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense
Integrin-based therapeutics could block inflammatory processes but they also impair host defence, limiting their usefulness. Here the authors report an anti-Mac1 antibody that blocks its interaction with pro-inflammatory ligand CD40L but not other ligands, and show that it can protect against sepsis in mice