2,139 research outputs found

    The last fifteen years of stagnation in Italy: A Business Cycle Accounting Perspective

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    In this paper, we investigate possible sources of declining economic growth performance in Italy starting around the middle of the ’90s. A long-run data analysis suggests that the poor performance of the Italian economy cannot be ascribed to an unfortunate business cycle contingency. The rest of the euro area countries have shown better performance, and the macroeconomic data show that the Italian economy has not grown as rapidly as these other European economies. We investigate the sources of economic fluctuations in Italy by applying the Business Cycle Accounting procedure introduced by Chari, Kehoe and McGrattan (2007). We analyze the relative importance of efficiency, labor, investment and government wedges for business cycles in Italy over the 1982-2008 period. We find that different wedges have played different roles during the period, but the efficiency wedge is revealed to be the main factor responsible for the stagnation phase beginning around 1995. Our findings also show that the improvement in labor market distortions that occurred in Italy during the ’90s provided an alleviating effect, preventing an even stronger slowdown in per capita output growth.

    Excess length of hospital stay due to healthcare acquired infections. Methodologies evaluation

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    BACKGROUND: Healthcare acquired infections (HAI) cause an increase of burden and in particular excess length of hospital stay (LOS) accounts for approximately up to 90% of total costs. Therefore accurate estimation of extra hospital stay due to healthcare acquired infections is very important. METHODS: The authors carried out a review comparing the principal methods internationally used for estimating the excess LOS attributable to healthcare acquired infections. RESULTS: The methods described and analysed are: 1) Implicit physician assessment; 2) appropriateness evaluation protocol; 3) unmatched case-control; 4) matched case-control; 5) regression analysis; 6) multistate model. The various methodologies are described underlining advantages and limits which researchers need to know before starting any economic analysis. CONCLUSIONS: Overall, studies taking into account the time-dependent nature of HAI show to give more precise and reliable results

    Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy

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    Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection. A 6-year retrospective surveillance study was conducted between 2010 and 2016 in 2 large administrative regions of Italy, located in the north (Liguria) and in the south (Sicily) of the country, to describe the burden and epidemiology of both B/Victoria and B/Yamagata lineages in different healthcare settings. Influenza B viruses were detected in 5 of 6 seasonal outbreaks, exceeding influenza A during the season 2012–2013. Most of influenza B infections were found in children aged ≤ 14 y and significant differences were observed in the age-groups infected by the different lineages. B/Victoria strains prevailed in younger population than B/Yamagata, but also were more frequently found in the community setting. Conversely, B/Yamagata viruses were prevalent among hospitalized cases suggesting their potential role in the development of more severe disease. The relative proportions of viral lineages varied from year to year, resulting in different lineage-level mismatch for the B component of trivalent influenza vaccine. Our findings confirmed the need for continuous virological surveillance of seasonal epidemics and bring attention to the adoption of universal influenza immunization program in the childhood. The use of tetravalent vaccine formulations may be useful to improve the prevention and control of the influenza burden in general population

    How much traffic is too much? Finding the right vehicle quota for a scenic mountain road in the Italian Alps

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    An effective yet neglected option to limit the detrimental effects of car traffic in natural tourist destinations is the imposition of vehicle quotas. Defining the right quota for a road system, however, may not be straightforward because of the complex connection between the number of vehicles entering the system and traffic levels across space and over time. In this paper, we present a novel approach to tackle this issue that combines agent-based modeling and standards of quality, and we use it to define an hourly quota aimed at limiting traffic congestion and demand for parking along a scenic road in the Dolomites (Italian Alps). The model is designed and calibrated using geospatial and traffic data, and the acceptability of the quotas is further tested according to the hourly modal splits they might induce. Our model simulations highlight that, by redistributing morning traffic inflows, the quota can almost eliminate congestion with only a negligible impact on overall traffic figures. Further, while traffic reductions of up to 35% may be needed to eliminate traffic-related issues, more reasonable reductions (i.e. 10–25%) may be enough to address most of those. From an empirical perspective, the paper shows the effectiveness of quotas in sustainable transport and tourism; from a policy and management perspective, it proposes an approach for the definition of an ideal quota. The design of a quota system, however, requires detailed implementation and communication strategies, and more advanced simulation tools to capture circulation patterns induced by such strategies

    Direct measurement of DNA-mediated adhesion between lipid bilayers

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    Multivalent interactions between deformable mesoscopic units are ubiquitous in biology, where membrane macromolecules mediate the interactions between neighbouring living cells and between cells and solid substrates. Lately, analogous artificial materials have been synthesised by functionalising the outer surface of compliant Brownian units, for example emulsion droplets and lipid vesicles, with selective linkers, in particular short DNA sequences. This development extended the range of applicability of DNA as a selective glue, originally applied to solid nano and colloidal particles. On very deformable lipid vesicles, the coupling between statistical effects of multivalent interactions and mechanical deformation of the membranes gives rise to complex emergent behaviours, as we recently contributed to demonstrate [Parolini et al., Nature Communications, 2015, 6, 5948]. Several aspects of the complex phenomenology observed in these systems still lack a quantitative experimental characterisation and fundamental understanding. Here we focus on the DNA-mediated multivalent interactions of a single liposome adhering to a flat supported bilayer. This simplified geometry enables the estimate of the membrane tension induced by the DNA-mediated adhesive forces acting on the liposome. Our experimental investigation is completed by morphological measurements and the characterisation of the DNA-melting transition, probed by in-situ F\"{o}rster Resonant Energy Transfer spectroscopy. Experimental results are compared with the predictions of an analytical theory that couples the deformation of the vesicle to a full description of the statistical mechanics of mobile linkers. With at most one fitting parameter, our theory is capable of semi-quantitatively matching experimental data, confirming the quality of the underlying assumptions.Comment: 16 pages, 7 figure

    Energetic plumes over the western Ross Sea continental slope

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    Rapid descent of dense Drygalski Trough (western Ross Sea, Antarctica) shelf water over the continental slope, within 100 to 250 m thick benthic plumes, is described. Speeds of up to 1.0 m/s are recorded flowing at an average angle of 35° to the isobaths, entraining ambient Lower Circumpolar Deep Water en route. This process is predominant in determining the concentration and placement of the shelf water injected into the deep sea as a precursor Antarctic Bottom Water. Nonetheless, a 4-hour duration pulse of undiluted shelf water was observed at depth (1407 m) directly north of the Drygalski Trough, moving at around 90 degrees to isobaths, and at a speed of 1.4 m/s. Thus the export of Ross Sea shelf water to the deep sea is accomplished within plumes descending at moderate angle to isobaths, punctuated by rapid downhill cascades

    Which affects affect the use of new technologies? Italian adaptation of the Internet Motive Questionnaire for Adolescents (IMQ-A) and criterion validity with problematic use and body dissatisfaction

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    Given the negative role of problematic use of new technological devices (NTD) in behavioral and psychological domains, the aim of the study is the Italian adaptation and validation of the Internet Motive Questionnaire for Adolescents (IMQ-A) in order to understand the motivation for the use of NTD. A total of 769 students 10-19 aged (M = 13.22, SD = 1.56) completed the IMQ-A, the Collins Figures Rating Scale, and two measures regarding the problematic NTD use, focused on overuse during the night and during meals. The IMQ-A showed adequate internal consistency with regard to its four subscales: Coping (α = .84), Social (α = .80), Enhancement (α = .80), and Conformity (α = .68) motives. However, with regard to factorial structure, a threefactor model (excluding Conformity subscale) showed slightly better fit indices than the original model. Coping motive was correlated with problematic NTD use and succeeded in predicting higher scores in body dissatisfaction as evidence of criterion-related and external validity. The Italian adaptation of the IMQ-A can be useful in both research and clinical fields, in order to propose alternative strategies for coping to users and to improve emotion regulation facets

    Organic and healthy: assessing the impact of claims and third-party certifications on premium price

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    Organic food consumption is steadily growing across a variety of product categories. While consumers are increasingly focused on the healthiness of the food they purchase, companies are experimenting alternative ways to communicate and guarantee the organic and health-related benefits of their products. This study explores the effect of different combinations of front-of-package (FoP) components on premium price. Specifically, we focus on the interaction and visual salience of FoP organic claims, health-related claims, and third-party organic certifications. Based on an analysis of grocery sales data and product packaging visuals, the study identifies FoP component combinations that could maximise premiums. We offer insights to marketing managers and companies involved in enhancing the communication of organic food benefits to consumers
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