516 research outputs found
A nearly zero-energy microgrid testbed laboratory: Centralized control strategy based on SCADA system
Currently, despite the use of renewable energy sources (RESs), distribution networks are facing problems, such as complexity and low productivity. Emerging microgrids (MGs) with RESs based on supervisory control and data acquisition (SCADA) are an effective solution to control, manage, and finally deal with these challenges. The development and success of MGs is highly dependent on the use of power electronic interfaces. The use of these interfaces is directly related to the progress of SCADA systems and communication infrastructures. The use of SCADA systems for the control and operation of MGs and active distribution networks promotes productivity and efficiency. This paper presents a real MG case study called the LAMBDA MG testbed laboratory, which has been implemented in the electrical department of the Sapienza University of Rome with a centralized energy management system (CEMS). The real-time results of the SCADA system show that a CEMS can create proper energy balance in a LAMBDA MG testbed and, consequently, minimize the exchange power of the LAMBDA MG and main grid
Developing a fuzzy expert system to predict the risk of neonatal death
Introduction: This study aims at developing a fuzzy expert system to predict the possibility of neonatal death. Materials and Methods: A questionnaire was given to Iranian neonatologists and the more important factors were identified based on their answers. Then, a computing model was designed considering the fuzziness of variables having the highest neonatal mortality risk. The inference engine used was Mamdani's method and the output was the risk of neonatal death given as a percentage. To validate the designed system, neonates' medical records real data at a Tehran hospital were used. MATLAB software was applied to build the model, and user interface was developed by C# programming in Visual Studio platform as bilingual (English and Farsi user interface). Results: According to the results, the accuracy, sensitivity, and specificity of the model were 90, 83 and 97, respectively. Conclusion: The designed fuzzy expert system for neonatal death prediction showed good accuracy as well as proper specificity, and could be utilized in general hospitals as a clinical decision support tool. ©2016 Reza Safdari, Maliheh Kadivar, Mostafa Langarizadeh, Ahmadreaza Farzaneh Nejad, Farzaneh Kermani
Strontium-and cobalt-doped multicomponent mesoporous bioactive glasses (MBGS) for potential use in bone tissue engineering applications
Mesoporous bioactive glasses (MBGs) offer suitable platforms for drug/ion delivery in tissue engineering strategies. The main goal of this study was to prepare strontium (Sr)-and cobalt (Co)-doped MBGs; strontium is currently used in the treatment of osteoporosis, and cobalt is known to exhibit pro-angiogenic effects. Sr-and Co-doped mesoporous glasses were synthesized for the first time in a multicomponent silicate system via the sol-gel method by using P123 as a structure-directing agent. The glassy state of the Sr-and Co-doped materials was confirmed by XRD before immersion in SBF, while an apatite-like layer was detected onto the surface of samples post-immersion. The textural characteristics of MBGs were confirmed by nitrogen adsorption/desorption measurements. In vitro experiments including MTT assay, Alizarin red staining, and cell attachment and migration showed the cytocompatibility of all the samples as well as their positive effects on osteoblast-like cell line MG-63. Early experiments with human umbilical vein endothelial cells also suggested the potential of these MBGs in the context of angiogenesis. In conclusion, the prepared materials were bioactive, showed the ability to improve osteoblast cell function in vitro and could be considered as valuable delivery vehicles for therapeutics, like Co2+ and Sr2+ ions
Hydroxyapatite Nanoparticles for Improved Cancer Theranostics
Beyond their well-known applications in bone tissue engineering, hydroxyapatite nanoparticles (HAp NPs) have also been showing great promise for improved cancer therapy. The chemical structure of HAp NPs offers excellent possibilities for loading and delivering a broad range of anticancer drugs in a sustained, prolonged, and targeted manner and thus eliciting lower complications than conventional chemotherapeutic strategies. The incorporation of specific therapeutic elements into the basic composition of HAp NPs is another approach, alone or synergistically with drug release, to provide advanced anticancer effects such as the capability to inhibit the growth and metastasis of cancer cells through activating specific cell signaling pathways. HAp NPs can be easily converted to smart anticancer agents by applying different surface modification treatments to facilitate the targeting and killing of cancer cells without significant adverse effects on normal healthy cells. The applications in cancer diagnosis for magnetic and nuclear in vivo imaging are also promising as the detection of solid tumor cells is now achievable by utilizing superparamagnetic HAp NPs. The ongoing research emphasizes the use of HAp NPs in fabricating three-dimensional scaffolds for the treatment of cancerous tissues or organs, promoting the regeneration of healthy tissue after cancer detection and removal. This review provides a summary of HAp NP applications in cancer theranostics, highlighting the current limitations and the challenges ahead for this field to open new avenues for research
The interaction in nuclear matter from a study of the reactions
The pion-production reactions were studied on
, , , and nuclei at an incident pion energy
of =283 MeV. Pions were detected in coincidence using the CHAOS
spectrometer. The experimental results are reduced to differential cross
sections and compared to both theoretical predictions and the reaction phase
space. The composite ratio between the
invariant masses on nuclei and on the nucleon is also presented. Near the
threshold pion pairs couple to when produced in
the reaction channel. There is a marked near-threshold
enhancement of which is consistent with theoretical
predictions addressing the partial restoration of chiral symmetry in nuclear
matter. Furthermore, the behaviour of is well
described when the restoration of chiral symmetry is combined with standard
P-wave renormalization of pions in nuclear matter. On the other hand, nuclear
matter only weakly influences , which displays a flat
behaviour throughout the energy range regardless of .Comment: 30 pages, 16 figures, PS format, accepted for publication in Nucl.
Phys
La métaplasie malpighienne dans le carcinome papillaire de la thyroïde
Introduction : la métaplasie malpighienne est rare au niveau de la thyroïde. Elle peut être associée à un processus pathologique tumoral ou inflammatoire.Matériels et méthodes : les auteurs se proposent de rapporter une observation de métaplasie malpighienne de la thyroïde associée à un carcinome papillaire diagnostiqué au service d’Anatomie et de Cytologie pathologiques du CHU Farhat Hached de Sousse et d’en discuter la pathogénie de cette métaplasie, ses circonstances de survenue et ses difficultés diagnostiques.Résultats : il s’agissait d’une fille âgée de 9 ans ayant consulté pour un nodule de la thyroïde. Une cytoponction de ce nodule était pratiquée et avait montré la présence de cellules tumorales d’un carcinome papillaire. Une thyroïdectomie totale avec curage triangulaire fonctionnel a été réalisée. L’examen anatomo-pathologique de la pièce a confirmé la présence d’un carcinome papillaire de la thyroïde avec présence au voisinage de la tumeur de plages de cellules malpighiennes d’allure non tumorale.Conclusion : bien que rare, la métaplasie malpighienne peut se voir dans la thyroïde. Elle doit être distinguée d’un carcinome épidermoïde de la thyroïde par la recherche systématique, devant tout foyer de métaplasie malpighienne, des signes de malignité.Mots clés : métaplasie malpighienne, carcinome papillaire, glande thyroïde
Prediction of neonatal deaths in NICUs: development and validation of machine learning models
Background: Prediction of neonatal deaths in NICUs is important for benchmarking and evaluating healthcare services in NICUs. Application of machine learning techniques can improve physicians� ability to predict the neonatal deaths. The aim of this study was to present a neonatal death risk prediction model using machine learning techniques. Methods: This study was conducted in Tehran, Iran in two phases. Initially, important risk factors in neonatal death were identified and then several machine learning models including Artificial Neural Network (ANN), decision tree (Random Forest (RF), C5.0 and CHART tree), Support Vector Machine (SVM), Bayesian Network and Ensemble models were developed. Finally, we prospectively applied these models to predict neonatal death in a NICU and followed up the neonates to compare the outcomes of these neonates with real outcomes. Results: 17 factors were considered important in neonatal mortality prediction. The highest Area Under the Curve (AUC) was achieved for the SVM and Ensemble models with 0.98. The best precision and specificity were 0.98 and 0.94, respectively for the RF model. The highest accuracy, sensitivity and F-score were achieved for the SVM model with 0.94, 0.95 and 0.96, respectively. The best performance of models in prospective evaluation was for the ANN, C5.0 and CHAID tree models. Conclusion: Using the developed machine learning models can help physicians predict the neonatal deaths in NICUs. © 2021, The Author(s)
Rectangular Symmetry Morphologies in a Topographically Templated Block Copolymer
Using an array of majority-block-functionalized posts makes it possible to locally control the self-assembly of a block copolymer and achieve several morphologies on a single substrate. A template consisting of a square symmetry array of posts produces a square-symmetry lattice of microdomains, which doubles the areal density of features.Semiconductor Research CorporationFENA CenterSemiconductor Research Corporation. Nanoscale Research InitiativeSingapore-MIT AllianceNational Science Foundation (U.S.)Taiwan Semiconductor Manufacturing CompanyTokyo Electron LimitedNational University of Singapor
A stochastic method for the energy management in hybrid electric vehicles
There are many approaches addressing the problem of optimal energy management in hybrid electric vehicles; however, most of them optimise the control strategy for particular driving cycles. This paper takes into account that the driving cycle is not a priori known to obtain a near-optimal solution. The proposed method is based on analysing the power demands in a given receding horizon to estimate future driving conditions and minimise the fuel consumption while cancelling the expected battery energy consumption after a defined time horizon. Simulations show that the proposed method allows charge sustainability providing near-optimal results. (C) 2014 Elsevier Ltd. All rights reserved.This research has been partially supported by Ministerio de Ciencia e Innovacion through Project TRA2010-16205 uDiesel and by the Conselleria de Educacio Cultura i Esports de la Generalitat Valenciana through Project GV/2103/044 AECOSPH.Payri González, F.; Guardiola, C.; Plá Moreno, B.; Blanco-Rodriguez, D. (2014). A stochastic method for the energy management in hybrid electric vehicles. Control Engineering Practice. 29:257-265. https://doi.org/10.1016/j.conengprac.2014.01.004S2572652
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