169 research outputs found

    Debating big data: A literature review on realizing value from big data

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    This is the final version. Available on open access from Elsevier via the DOI in this recordBig data has been considered to be a breakthrough technological development over recent years. Notwithstanding, we have as yet limited understanding of how organizations translate its potential into actual social and economic value. We conduct an in-depth systematic review of IS literature on the topic and identify six debates central to how organizations realize value from big data, at different levels of analysis. Based on this review, we identify two socio-technical features of big data that influence value realization: portability and interconnectivity. We argue that, in practice, organizations need to continuously realign work practices, organizational models, and stakeholder interests in order to reap the benefits from big data. We synthesize the findings by means of an integrated model

    RELBET 4.0 user's guide

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    This manual describes the operation and use of RELBET 4.0 implemented on the Hewlett Packard model 9000. The RELBET System is an integrated collection of computer programs which support the analysis and post-flight reconstruction of vehicle to vehicle relative trajectories of two on-orbit free-flying vehicles: the Space Shuttle Orbiter and some other free-flyer. The manual serves both as a reference and as a training guide. Appendices provide experienced users with details and full explanations of program usage. The body of the manual introduces new users to the system by leading them through a step by step example of a typical production. This should equip the new user both to execute a typical production process and to understand the most significant variables in that process

    Controle op gezondheid

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    Het op tijd signaleren van gezondheidsproblemen is belangrijk. De behandeling en verzorging van de dieren kan dan beter worden uitgevoerd. Systemen waarbij de dieren in groepen gehouden worden vragen een andere manier van controle dan conventionele systemen waarbij dieren individueel gehuisvest zijn

    Red and Green Algal Origin of Diatom Membrane Transporters: Insights into Environmental Adaptation and Cell Evolution

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    Membrane transporters (MTs) facilitate the movement of molecules between cellular compartments. The evolutionary history of these key components of eukaryote genomes remains unclear. Many photosynthetic microbial eukaryotes (e.g., diatoms, haptophytes, and dinoflagellates) appear to have undergone serial endosymbiosis and thereby recruited foreign genes through endosymbiotic/horizontal gene transfer (E/HGT). Here we used the diatoms Thalassiosira pseudonana and Phaeodactylum tricornutum as models to examine the evolutionary origin of MTs in this important group of marine primary producers. Using phylogenomics, we used 1,014 diatom MTs as query against a broadly sampled protein sequence database that includes novel genome data from the mesophilic red algae Porphyridium cruentum and Calliarthron tuberculosum, and the stramenopile Ectocarpus siliculosus. Our conservative approach resulted in 879 maximum likelihood trees of which 399 genes show a non-lineal history between diatoms and other eukaryotes and prokaryotes (at the bootstrap value ≥70%). Of the eukaryote-derived MTs, 172 (ca. 25% of 697 examined phylogenies) have members of both red/green algae as sister groups, with 103 putatively arising from green algae, 19 from red algae, and 50 have an unresolved affiliation to red and/or green algae. We used topology tests to analyze the most convincing cases of non-lineal gene history in which red and/or green algae were nested within stramenopiles. This analysis showed that ca. 6% of all trees (our most conservative estimate) support an algal origin of MTs in stramenopiles with the majority derived from green algae. Our findings demonstrate the complex evolutionary history of photosynthetic eukaryotes and indicate a reticulate origin of MT genes in diatoms. We postulate that the algal-derived MTs acquired via E/HGT provided diatoms and other related microbial eukaryotes the ability to persist under conditions of fluctuating ocean chemistry, likely contributing to their great success in marine environments
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