103 research outputs found
ΠΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΌΠΎΠ΄Π΅Π»Ρ ΠΏΠΎΡΠΎΠΊΠΎΠ² ΠΏΠΎΠΊΡΠΏΠ°ΡΠ΅Π»Π΅ΠΉ Π΄Π²ΡΡ ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ²ΠΎΠΉ ΡΠΎΡΠ³ΠΎΠ²ΠΎΠΉ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΈ Π² Π²ΠΈΠ΄Π΅ ΡΠΈΡΡΠ΅ΠΌΡ ΠΌΠ°ΡΡΠΎΠ²ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ»ΡΠΆΠΈΠ²Π°Π½ΠΈΡ Ρ ΠΏΠΎΠ²ΡΠΎΡΠ½ΡΠΌΠΈ ΠΎΠ±ΡΠ°ΡΠ΅Π½ΠΈΡΠΌΠΈ ΠΊ Π±Π»ΠΎΠΊΠ°ΠΌ
ΠΠΎΡΡΡΠΎΠ΅Π½Π° ΠΌΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΌΠΎΠ΄Π΅Π»Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΡΠΎΠΊΠ° ΠΏΠΎΠΊΡΠΏΠ°ΡΠ΅Π»Π΅ΠΉ ΡΠΎΡΠ³ΠΎΠ²ΠΎΠΉ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΈ Π² Π²ΠΈΠ΄Π΅ ΡΠΈΡΡΠ΅ΠΌΡ ΠΏΠ°ΡΠ°Π»Π»Π΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ»ΡΠΆΠΈΠ²Π°Π½ΠΈΡ ΠΊΡΠ°ΡΠ½ΡΡ
Π·Π°ΡΠ²ΠΎΠΊ Ρ ΠΏΠΎΠ²ΡΠΎΡΠ½ΡΠΌ ΠΎΠ±ΡΠ°ΡΠ΅Π½ΠΈΠ΅ΠΌ ΠΈ Π½Π΅ΠΎΠ³ΡΠ°Π½ΠΈΡΠ΅Π½Π½ΡΠΌ ΡΠΈΡΠ»ΠΎΠΌ ΠΎΠ±ΡΠ»ΡΠΆΠΈΠ²Π°ΡΡΠΈΡ
ΠΏΡΠΈΠ±ΠΎΡΠΎΠ², ΠΏΠΎΠ»ΡΡΠ΅Π½ΠΎ Π²ΡΡΠ°ΠΆΠ΅Π½ΠΈΠ΅ Π΄Π»Ρ ΠΌΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΠΆΠΈΠ΄Π°Π½ΠΈΡ ΠΊΠ°ΠΏΠΈΡΠ°Π»Π° ΡΠΎΡΠ³ΠΎΠ²ΠΎΠΉ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΈ, Π° ΡΠ°ΠΊΠΆΠ΅ Π½Π°ΠΉΠ΄Π΅Π½ΠΎ ΡΡΠ»ΠΎΠ²ΠΈΠ΅ Π΄Π»Ρ ΡΡΡΠ΅ΡΡΠ²ΠΎΠ²Π°Π½ΠΈΡ ΠΌΠ°ΠΊΡΠΈΠΌΡΠΌΠ° ΡΡΠΎΠΉ ΡΡΠ½ΠΊΡΠΈΠΈ. ΠΠ»Ρ ΠΊΠΎΠ½ΠΊΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΈΠΌΠ΅ΡΠ° ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΎ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ΅ ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠ΅ ΡΡΠΎΠΈΠΌΠΎΡΡΠΈ ΠΏΠΎΠ΄Π°ΡΠΊΠ° ΠΊ ΡΡΠ΅Π΄Π½Π΅ΠΉ ΡΡΠΎΠΈΠΌΠΎΡΡΠΈ ΠΏΠΎΠΊΡΠΏΠΊΠΈ, ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΠ²Π°ΡΡΠ΅Π΅ ΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΡΡ ΠΏΡΠΈΠ±ΡΠ»Ρ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΈ
Thermal characterization and mapping of the fumeroles on Vulcano, Italy: Potential analogues for Martian terrains
Heat transfer in separated flows on the pressure side of turbine blades
Heat transfer in separated flows on the pressure side of a typical high lift turbine profile is numerically investigated by means of an in-house CFD code. The numerical code was first validated on attached flows in turbine blades. To obtain flow separation cases, the profile is subject to large negative incidences so that a separation bubble is obtained at the pressure side. The numerical results are compared to available experimental data for code validation. It is shown how local minima and maxima values of the heat transfer coefficient are related to the separation and reattachment points, where the velocity component perpendicular to the wall is shown to have a significant effect on the heat transfe
European economic constitution and the transformation of democracy : on class and the state of law
In the context of contemporary analyses of the Europe Union as a post-democratic form of economic governance, this article explores the (ordo)liberal character of monetary union as a regime of imposed liberty. The argument holds that rather than forcing the member states into retreat, the economic constitution of Europe strengthens their liberal foundation, securing their utility as the organised force of a mode of social reproduction founded on free labour. It develops the character of the liberal state as the political form of a free market economy with reference to Adam Smithβs classical political economy and the German ordoliberal tradition, which calls for a rule-based system of federated forms of economic governance to secure a free labour economy in conditions of mass democratic aspirations for a freedom from want. It explores the rationale of the ordoliberal distinction between the liberal character and the democratic character of the state and, in this context, assesses the meaning of liberal democracy in a post-democratic Eurozone
Circumvention of orbital symmetry restraints by 1,3-H-shifts of enolic radical cations
Polar Invasion and Translocation of Neisseria meningitidis and Streptococcus suis in a Novel Human Model of the Blood-Cerebrospinal Fluid Barrier
Acute bacterial meningitis is a life-threatening disease in humans. Discussed as entry sites for pathogens into the brain are the blood-brain and the blood-cerebrospinal fluid barrier (BCSFB). Although human brain microvascular endothelial cells (HBMEC) constitute a well established human in vitro model for the blood-brain barrier, until now no reliable human system presenting the BCSFB has been developed. Here, we describe for the first time a functional human BCSFB model based on human choroid plexus papilloma cells (HIBCPP), which display typical hallmarks of a BCSFB as the expression of junctional proteins and formation of tight junctions, a high electrical resistance and minimal levels of macromolecular flux when grown on transwell filters. Importantly, when challenged with the zoonotic pathogen Streptococcus suis or the human pathogenic bacterium Neisseria meningitidis the HIBCPP show polar bacterial invasion only from the physiologically relevant basolateral side. Meningococcal invasion is attenuated by the presence of a capsule and translocated N. meningitidis form microcolonies on the apical side of HIBCPP opposite of sites of entry. As a functionally relevant human model of the BCSFB the HIBCPP offer a wide range of options for analysis of disease-related mechanisms at the choroid plexus epithelium, especially involving human pathogens
Ludwig von Mises and the 'Ordo-Interventionists' More than Just Aggression and Contempt?
Effect of roughness and unsteadiness on the performance of a new LPT blade at low Reynolds numbers
This paper presents a study of the performance of a high lift profile for low pressure turbines at Reynolds numbers lower than in previous investigations. The separate and combined effects of roughness and wake passing are compared. The effect of incidence on cascade losses is also evaluated. The experimental investigation was carried out in the high speed wind tunnel of Whittle Laboratory, University of Cambridge. This is a closed circuit, continuous wind tunnel where the Reynolds number and Mach number can be fixed independently. The unsteadiness caused by wake passing in front of the blades is reproduced using a wake generator with rotating bars. The results obtained confirm that the beneficial effect of unsteadiness on losses is also present at the lowest Reynolds number examined (Re3 = 0.2Γ105). Roughening the surface also had a beneficial effect on the losses but this effect vanishes at the lower Reynolds numbers, i.e. (Re3 0.3Γ105), where the surface becomes hydraulically smooth. The present study suggests that a blade with as-cast surface roughness has a lower loss than a polished one
Effect of roughness and unsteadiness on the performance of a new LPT blade at low Reynolds numbers
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